Articles with public access mandates - Sergio ValenteLearn more
Not available anywhere: 14
Review
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ...
Journal of medicinal chemistry 57 (1), 42-55, 2014
Mandates: Fondazione Cariplo, Government of Italy
Review
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent
P Vianello, OA Botrugno, A Cappa, R Dal Zuffo, P Dessanti, A Mai, ...
Journal of Medicinal Chemistry 59 (4), 1501-1517, 2016
Mandates: Fondazione Cariplo, Government of Italy
Review
Emerging approaches for histone deacetylase inhibitor drug discovery
C Zwergel, S Valente, C Jacob, A Mai
Expert opinion on drug discovery 10 (6), 599-613, 2015
Mandates: Government of Italy
Review
Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity
M Erburu, I Muñoz-Cobo, J Domínguez-Andrés, E Beltran, T Suzuki, A Mai, ...
European Neuropsychopharmacology 25 (11), 2036-2048, 2015
Mandates: Government of Spain, Government of Italy
Review
Sirtuin modulators: an updated patent review (2012–2014)
P Mellini, S Valente, A Mai
Expert opinion on therapeutic patents 25 (1), 5-15, 2015
Mandates: Government of Italy
Review
Identification of novel quinazoline derivatives as potent antiplasmodial agents
A Bouchut, D Rotili, C Pierrot, S Valente, S Lafitte, J Schultz, U Hoglund, ...
European Journal of Medicinal Chemistry 161, 277-291, 2019
Mandates: US National Institutes of Health, National Health and Medical Research …
Review
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: role of Hsp90 acetylation
S Panella, ME Marcocci, I Celestino, S Valente, C Zwergel, DD Li Puma, ...
Future medicinal chemistry 8 (17), 2017-2031, 2016
Mandates: Government of Italy
Review
Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer
G Stazi, R Fioravanti, A Mai, A Mattevi, S Valente
Current opinion in chemical biology 50, 89-100, 2019
Mandates: Government of Italy
Review
Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo
A Schlüter, B Aksan, R Fioravanti, S Valente, A Mai, D Mauceri
Molecular neurobiology 56, 8018-8034, 2019
Mandates: German Research Foundation, Government of Italy, AIRC Foundation for Cancer …
Review
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice
A Lapucci, L Cavone, D Buonvicino, R Felici, E Gerace, C Zwergel, ...
Neuroscience Letters 656, 120-125, 2017
Mandates: Government of Italy
Review
Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene
V Nobile, F Palumbo, S Lanni, V Ghisio, A Vitali, M Castagnola, ...
Human Genetics 139, 227-245, 2020
Mandates: Fondazione Telethon, Italy, Government of Italy
Review
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
G Stazi, C Battistelli, V Piano, R Mazzone, B Marrocco, S Marchese, ...
European Journal of Medicinal Chemistry 163, 722-735, 2019
Mandates: Government of Italy
Review
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells
E Di Bello, V Sian, G Bontempi, C Zwergel, R Fioravanti, B Noce, ...
European Journal of Medicinal Chemistry 247, 115022, 2023
Mandates: Government of Italy
Review
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages
B Noce, E Di Bello, C Zwergel, R Fioravanti, S Valente, D Rotili, A Masotti, ...
ChemMedChem 18 (3), e202200510, 2023
Mandates: Swiss National Science Foundation
Available somewhere: 82
Review
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
Mandates: US National Institutes of Health, Health Research Board, Ireland, UK Medical …
Review
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
D Palacios, C Mozzetta, S Consalvi, G Caretti, V Saccone, V Proserpio, ...
Cell stem cell 7 (4), 455-469, 2010
Mandates: US National Institutes of Health, Fondazione Telethon, Italy
Review
Oxidative stress and epigenetic regulation in ageing and age-related diseases
C Cencioni, F Spallotta, F Martelli, S Valente, A Mai, AM Zeiher, ...
International journal of molecular sciences 14 (9), 17643-17663, 2013
Mandates: Government of Italy
Review
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue
A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ...
diabetes 62 (3), 732-742, 2013
Mandates: US National Institutes of Health, Fondazione Cariplo
Review
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
JH Kalin, M Wu, AV Gomez, Y Song, J Das, D Hayward, N Adejola, M Wu, ...
Nature communications 9 (1), 53, 2018
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Review
Epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors
A Mai, D Cheng, MT Bedford, S Valente, A Nebbioso, A Perrone, ...
Journal of medicinal chemistry 51 (7), 2279-2290, 2008
Mandates: US National Institutes of Health
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