Articles with public access mandates - Sergio ValenteLearn more
OverallGovernment of ItalyNIHAIRC Foundation for Cancer Research in ItalyEuropean CommissionFondazione CariploTelethonINSERMDFGFRQSNWOFCTCancer Research UKWellcomeGovernment of SpainKWFSNSFDoDAHANHMRCFWOGenome CanadaNSFCBanking Foundation "la Caixa"HRBBBSRCMRCParkinson's UKWorldwide Cancer Research, UKFNRANRSCLV Foundation, USARoyal Society UK
Not available anywhere: 14
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities
D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ...
Journal of medicinal chemistry 57 (1), 42-55, 2014
Mandates: Fondazione Cariplo, Government of Italy
Discovery of a novel inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) as orally active antitumor agent
P Vianello, OA Botrugno, A Cappa, R Dal Zuffo, P Dessanti, A Mai, ...
Journal of Medicinal Chemistry 59 (4), 1501-1517, 2016
Mandates: Fondazione Cariplo, Government of Italy
Emerging approaches for histone deacetylase inhibitor drug discovery
C Zwergel, S Valente, C Jacob, A Mai
Expert opinion on drug discovery 10 (6), 599-613, 2015
Mandates: Government of Italy
Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity
M Erburu, I Muñoz-Cobo, J Domínguez-Andrés, E Beltran, T Suzuki, A Mai, ...
European Neuropsychopharmacology 25 (11), 2036-2048, 2015
Mandates: Government of Spain, Government of Italy
Sirtuin modulators: an updated patent review (2012–2014)
P Mellini, S Valente, A Mai
Expert opinion on therapeutic patents 25 (1), 5-15, 2015
Mandates: Government of Italy
Identification of novel quinazoline derivatives as potent antiplasmodial agents
A Bouchut, D Rotili, C Pierrot, S Valente, S Lafitte, J Schultz, U Hoglund, ...
European Journal of Medicinal Chemistry 161, 277-291, 2019
Mandates: US National Institutes of Health, National Health and Medical Research …
MC1568 inhibits HDAC6/8 activity and influenza A virus replication in lung epithelial cells: role of Hsp90 acetylation
S Panella, ME Marcocci, I Celestino, S Valente, C Zwergel, DD Li Puma, ...
Future medicinal chemistry 8 (17), 2017-2031, 2016
Mandates: Government of Italy
Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer
G Stazi, R Fioravanti, A Mai, A Mattevi, S Valente
Current opinion in chemical biology 50, 89-100, 2019
Mandates: Government of Italy
Histone deacetylases contribute to excitotoxicity-triggered degeneration of retinal ganglion cells in vivo
A Schlüter, B Aksan, R Fioravanti, S Valente, A Mai, D Mauceri
Molecular neurobiology 56, 8018-8034, 2019
Mandates: German Research Foundation, Government of Italy, AIRC Foundation for Cancer …
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice
A Lapucci, L Cavone, D Buonvicino, R Felici, E Gerace, C Zwergel, ...
Neuroscience Letters 656, 120-125, 2017
Mandates: Government of Italy
Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene
V Nobile, F Palumbo, S Lanni, V Ghisio, A Vitali, M Castagnola, ...
Human Genetics 139, 227-245, 2020
Mandates: Fondazione Telethon, Italy, Government of Italy
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
G Stazi, C Battistelli, V Piano, R Mazzone, B Marrocco, S Marchese, ...
European Journal of Medicinal Chemistry 163, 722-735, 2019
Mandates: Government of Italy
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells
E Di Bello, V Sian, G Bontempi, C Zwergel, R Fioravanti, B Noce, ...
European Journal of Medicinal Chemistry 247, 115022, 2023
Mandates: Government of Italy
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages
B Noce, E Di Bello, C Zwergel, R Fioravanti, S Valente, D Rotili, A Masotti, ...
ChemMedChem 18 (3), e202200510, 2023
Mandates: Swiss National Science Foundation
Available somewhere: 82
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
Mandates: US National Institutes of Health, Health Research Board, Ireland, UK Medical …
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
D Palacios, C Mozzetta, S Consalvi, G Caretti, V Saccone, V Proserpio, ...
Cell stem cell 7 (4), 455-469, 2010
Mandates: US National Institutes of Health, Fondazione Telethon, Italy
Oxidative stress and epigenetic regulation in ageing and age-related diseases
C Cencioni, F Spallotta, F Martelli, S Valente, A Mai, AM Zeiher, ...
International journal of molecular sciences 14 (9), 17643-17663, 2013
Mandates: Government of Italy
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue
A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ...
diabetes 62 (3), 732-742, 2013
Mandates: US National Institutes of Health, Fondazione Cariplo
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors
JH Kalin, M Wu, AV Gomez, Y Song, J Das, D Hayward, N Adejola, M Wu, ...
Nature communications 9 (1), 53, 2018
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors
A Mai, D Cheng, MT Bedford, S Valente, A Nebbioso, A Perrone, ...
Journal of medicinal chemistry 51 (7), 2279-2290, 2008
Mandates: US National Institutes of Health
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