Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2 O Riccio, ME Van Gijn, AC Bezdek, L Pellegrinet, JH Van Es, ... EMBO reports 9 (4), 377-383, 2008 | 471 | 2008 |
Epstein‐Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP‐J kappa, the homologue of Drosophila … U Zimber‐Strobl, LJ Strobl, C Meitinger, R Hinrichs, T Sakai, T Furukawa, ... The EMBO journal 13 (20), 4973-4982, 1994 | 264 | 1994 |
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma PK Mazur, H Einwächter, M Lee, B Sipos, H Nakhai, R Rad, ... Proceedings of the National Academy of Sciences 107 (30), 13438-13443, 2010 | 262 | 2010 |
Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation V Besseyrias, E Fiorini, LJ Strobl, U Zimber-Strobl, A Dumortier, U Koch, ... The Journal of experimental medicine 204 (2), 331-343, 2007 | 242 | 2007 |
Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice F Geisler, F Nagl, PK Mazur, M Lee, U Zimber‐Strobl, LJ Strobl, F Radtke, ... Hepatology 48 (2), 607-616, 2008 | 238 | 2008 |
Hold back of RNA polymerase II at the transcription start site mediates down‐regulation of c‐myc in vivo. LJ Strobl, D Eick The EMBO Journal 11 (9), 3307-3314, 1992 | 229 | 1992 |
EBNA2 and Notch signalling in Epstein–Barr virus mediated immortalization of B lymphocytes U Zimber-Strobl, LJ Strobl Seminars in cancer biology 11 (6), 423-434, 2001 | 181 | 2001 |
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis C Homig-Holzel, C Hojer, J Rastelli, S Casola, LJ Strobl, W Müller, ... The Journal of experimental medicine 205 (6), 1317-1329, 2008 | 179 | 2008 |
The Spi‐1/PU. 1 and Spi‐B ets family transcription factors and the recombination signal binding protein RBP‐J kappa interact with an Epstein‐Barr virus nuclear antigen 2 … G Laux, B Adam, LJ Strobl, F Moreau‐Gachelin The EMBO journal 13 (23), 5624-5632, 1994 | 173 | 1994 |
Notch1 and Notch2 receptors influence progressive hair graying in a dose‐dependent manner K Schouwey, V Delmas, L Larue, U Zimber‐Strobl, LJ Strobl, F Radtke, ... Developmental dynamics: an official publication of the American Association …, 2007 | 151 | 2007 |
RBP-L, a transcription factor related to RBP-Jκ S Minoguchi, Y Taniguchi, H Kato, T Okazaki, LJ Strobl, U Zimber-Strobl, ... Molecular and cellular biology 17 (5), 2679-2687, 1997 | 149 | 1997 |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling J Gamrekelashvili, R Giagnorio, J Jussofie, O Soehnlein, J Duchene, ... Nature communications 7 (1), 12597, 2016 | 147 | 2016 |
Activated Notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2 LJ Strobl, H Höfelmayr, G Marschall, M Brielmeier, GW Bornkamm, ... Journal of virology 74 (4), 1727-1735, 2000 | 120 | 2000 |
Activated Notch1 can transiently substitute for EBNA2 in the maintenance of proliferation of LMP1-expressing immortalized B cells H Höfelmayr, LJ Strobl, G Marschall, GW Bornkamm, U Zimber-Strobl Journal of virology 75 (5), 2033-2040, 2001 | 107 | 2001 |
Functional replacement of the intracellular region of the Notch1 receptor by Epstein-Barr virus nuclear antigen 2 T Sakai, Y Taniguchi, K Tamura, S Minoguchi, T Fukuhara, LJ Strobl, ... Journal of virology 72 (7), 6034-6039, 1998 | 107 | 1998 |
Both Epstein-Barr viral nuclear antigen 2 (EBNA2) and activated Notch1 transactivate genes by interacting with the cellular protein RBP-Jκ LJ Strobl, H Höfelmayr, C Stein, G Marschall, M Brielmeier, G Laux, ... Immunobiology 198 (1-3), 299-306, 1997 | 103 | 1997 |
Conditional ablation of Notch signaling in pancreatic development H Nakhai, JT Siveke, B Klein, L Mendoza-Torres, PK Mazur, H Algül, ... Oxford University Press for The Company of Biologists Limited 135 (16), 2757 …, 2008 | 97 | 2008 |
CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling F Hampel, S Ehrenberg, C Hojer, A Draeseke, G Marschall-Schröter, ... Blood, The Journal of the American Society of Hematology 118 (24), 6321-6331, 2011 | 94 | 2011 |
Process for the preparation of human monoclonal antibodies and their use GW Bornkamm, D Eick, B Kempkes, NM Jochner, LJ Strobl US Patent 5,798,230, 1998 | 85 | 1998 |
Notch1 and Notch2 in podocytes play differential roles during diabetic nephropathy development MT Sweetwyne, A Gruenwald, T Niranjan, R Nishinakamura, LJ Strobl, ... Diabetes 64 (12), 4099-4111, 2015 | 74 | 2015 |