A TALE nuclease architecture for efficient genome editing JC Miller, S Tan, G Qiao, KA Barlow, J Wang, DF Xia, X Meng, ... Nature biotechnology 29 (2), 143-148, 2011 | 2995 | 2011 |
Highly efficient endogenous human gene correction using designed zinc-finger nucleases FD Urnov, JC Miller, YL Lee, CM Beausejour, JM Rock, S Augustus, ... Nature 435 (7042), 646-651, 2005 | 2219 | 2005 |
Genetic engineering of human pluripotent cells using TALE nucleases D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao, JP Cassady, GJ Cost, ... Nature biotechnology 29 (8), 731-734, 2011 | 1579 | 2011 |
An improved zinc-finger nuclease architecture for highly specific genome editing JC Miller, MC Holmes, J Wang, DY Guschin, YL Lee, I Rupniewski, ... Nature biotechnology 25 (7), 778-785, 2007 | 1518 | 2007 |
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases EE Perez, J Wang, JC Miller, Y Jouvenot, KA Kim, O Liu, N Wang, G Lee, ... Nature biotechnology 26 (7), 808-816, 2008 | 1401 | 2008 |
Distinct factors control histone variant H3. 3 localization at specific genomic regions AD Goldberg, LA Banaszynski, KM Noh, PW Lewis, SJ Elsaesser, ... Cell 140 (5), 678-691, 2010 | 1390 | 2010 |
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases D Hockemeyer, F Soldner, C Beard, Q Gao, M Mitalipova, RC DeKelver, ... Nature biotechnology 27 (9), 851-857, 2009 | 1303 | 2009 |
Knockout rats via embryo microinjection of zinc-finger nucleases AM Geurts, GJ Cost, Y Freyvert, B Zeitler, JC Miller, VM Choi, SS Jenkins, ... Science 325 (5939), 433-433, 2009 | 1222 | 2009 |
Precise genome modification in the crop species Zea mays using zinc-finger nucleases VK Shukla, Y Doyon, JC Miller, RC DeKelver, EA Moehle, SE Worden, ... Nature 459 (7245), 437-441, 2009 | 1209 | 2009 |
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases Y Doyon, JM McCammon, JC Miller, F Faraji, C Ngo, GE Katibah, ... Nature biotechnology 26 (6), 702-708, 2008 | 1162 | 2008 |
Targeted genome editing across species using ZFNs and TALENs AJ Wood, TW Lo, B Zeitler, CS Pickle, EJ Ralston, AH Lee, R Amora, ... Science 333 (6040), 307-307, 2011 | 970 | 2011 |
Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor W Deng, J Lee, H Wang, J Miller, A Reik, PD Gregory, A Dean, GA Blobel Cell 149 (6), 1233-1244, 2012 | 837 | 2012 |
An unbiased genome-wide analysis of zinc-finger nuclease specificity R Gabriel, A Lombardo, A Arens, JC Miller, P Genovese, C Kaeppel, ... Nature biotechnology 29 (9), 816-823, 2011 | 733 | 2011 |
A rapid and general assay for monitoring endogenous gene modification DY Guschin, AJ Waite, GE Katibah, JC Miller, MC Holmes, EJ Rebar Engineered Zinc Finger Proteins: Methods and Protocols, 247-256, 2010 | 678 | 2010 |
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR H Torikai, A Reik, PQ Liu, Y Zhou, L Zhang, S Maiti, H Huls, JC Miller, ... Blood, The Journal of the American Society of Hematology 119 (24), 5697-5705, 2012 | 669 | 2012 |
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures Y Doyon, TD Vo, MC Mendel, SG Greenberg, J Wang, DF Xia, JC Miller, ... Nature methods 8 (1), 74-79, 2011 | 532 | 2011 |
Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases Y Santiago, E Chan, PQ Liu, S Orlando, L Zhang, FD Urnov, MC Holmes, ... Proceedings of the National Academy of Sciences 105 (15), 5809-5814, 2008 | 490 | 2008 |
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome RC DeKelver, VM Choi, EA Moehle, DE Paschon, D Hockemeyer, ... Genome research 20 (8), 1133-1142, 2010 | 372 | 2010 |
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors H Torikai, A Reik, F Soldner, EH Warren, C Yuen, Y Zhou, DL Crossland, ... Blood, The Journal of the American Society of Hematology 122 (8), 1341-1349, 2013 | 360 | 2013 |
In vivo genome editing of the albumin locus as a platform for protein replacement therapy R Sharma, XM Anguela, Y Doyon, T Wechsler, RC DeKelver, S Sproul, ... Blood, The Journal of the American Society of Hematology 126 (15), 1777-1784, 2015 | 354 | 2015 |