Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85, 367-485, 2011 | 646 | 2011 |
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop D Kirkland, S Pfuhler, D Tweats, M Aardema, R Corvi, F Darroudi, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 628 (1 …, 2007 | 481 | 2007 |
The in vivo comet assay: use and status in genotoxicity testing S Brendler-Schwaab, A Hartmann, S Pfuhler, G Speit Mutagenesis 20 (4), 245-254, 2005 | 363 | 2005 |
Detection of DNA‐crosslinking agents with the alkaline comet assay S Pfuhler, H Uwe Wolf Environmental and molecular mutagenesis 27 (3), 196-201, 1996 | 255 | 1996 |
Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type P Fowler, K Smith, J Young, L Jeffrey, D Kirkland, S Pfuhler, P Carmichael Mutation Research/Genetic Toxicology and Environmental Mutagenesis 742 (1-2 …, 2012 | 233 | 2012 |
The BlueScreen HC assay to predict the genotoxic potential of fragrance materials Y Thakkar, K Joshi, C Hickey, J Wahler, B Wall, S Etter, B Smith, P Griem, ... Mutagenesis 37 (1), 13-23, 2022 | 199 | 2022 |
ECVAM retrospective validation of in vitro micronucleus test (MNT) R Corvi, S Albertini, T Hartung, S Hoffmann, D Maurici, S Pfuhler, ... Mutagenesis 23 (4), 271-283, 2008 | 174 | 2008 |
Measuring DNA modifications with the comet assay: a compendium of protocols A Collins, P Møller, G Gajski, S Vodenková, A Abdulwahed, D Anderson, ... Nature protocols 18 (3), 929-989, 2023 | 142 | 2023 |
Exercise-induced DNA effects in human leukocytes are not accompanied by increased formation of 8-hydroxy-2′-deoxyguanosine or induction of micronuclei A Hartmann, S Pfuhler, C Dennog, D Germadnik, A Pilger, G Speit Free Radical Biology and Medicine 24 (2), 245-251, 1998 | 136 | 1998 |
Use of Human In Vitro Skin Models for Accurate and Ethical Risk Assessment: Metabolic Considerations NJ Hewitt, RJ Edwards, E Fritsche, C Goebel, P Aeby, J Scheel, ... toxicological sciences 133 (2), 209-217, 2013 | 123 | 2013 |
In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop S Pfuhler, M Fellows, J van Benthem, R Corvi, R Curren, K Dearfield, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 723 (2 …, 2011 | 121 | 2011 |
In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results DJ Kirkland, M Aardema, N Banduhn, P Carmichael, R Fautz, JR Meunier, ... Mutagenesis 22 (3), 161-175, 2007 | 117 | 2007 |
Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not TR Downs, ME Crosby, T Hu, S Kumar, A Sullivan, K Sarlo, B Reeder, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 745 (1-2 …, 2012 | 115 | 2012 |
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I … D Kirkland, E Zeiger, F Madia, N Gooderham, P Kasper, A Lynch, T Morita, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 775, 55-68, 2014 | 111 | 2014 |
Pyrrolizidine alkaloids in food and phytomedicine: Occurrence, exposure, toxicity, mechanisms, and risk assessment-A review D Schrenk, L Gao, G Lin, C Mahony, PPJ Mulder, A Peijnenburg, ... Food and Chemical Toxicology 136, 111107, 2020 | 102 | 2020 |
Reduction of use of animals in regulatory genotoxicity testing: identification and implementation opportunities—report from an ECVAM workshop S Pfuhler, D Kirkland, P Kasper, M Hayashi, P Vanparys, P Carmichael, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 680 (1-2 …, 2009 | 100 | 2009 |
Genotoxicity assessment of nanomaterials: recommendations on best practices, assays, and methods R Elespuru, S Pfuhler, MJ Aardema, T Chen, SH Doak, A Doherty, ... Toxicological Sciences 164 (2), 391-416, 2018 | 98 | 2018 |
The Cosmetics Europe strategy for animal-free genotoxicity testing: project status up-date S Pfuhler, R Fautz, G Ouedraogo, A Latil, J Kenny, C Moore, W Diembeck, ... Toxicology in Vitro 28 (1), 18-23, 2014 | 81 | 2014 |
Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement P Fowler, R Smith, K Smith, J Young, L Jeffrey, D Kirkland, S Pfuhler, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 747 (1 …, 2012 | 80 | 2012 |
Relative potency of fifteen pyrrolizidine alkaloids to induce DNA damage as measured by micronucleus induction in HepaRG human liver cells A Allemang, C Mahony, C Lester, S Pfuhler Food and chemical toxicology 121, 72-81, 2018 | 78 | 2018 |