Articles with public access mandates - Philip HieterLearn more
Not available anywhere: 1
Mapping Synthetic Dosage Lethal Genetic Interactions in Saccharomyces cerevisiae
A Hamza, L Amitzi, S Duffy, P Hieter
Mapping Genetic Interactions, 39-56, 2021
Mandates: Canadian Institutes of Health Research
Available somewhere: 50
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map
SR Collins, KM Miller, NL Maas, A Roguev, J Fillingham, CS Chu, ...
Nature 446 (7137), 806-810, 2007
Mandates: Genome Canada
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers
TD Barber, K McManus, KWY Yuen, M Reis, G Parmigiani, D Shen, ...
Proceedings of the National Academy of Sciences 105 (9), 3443-3448, 2008
Mandates: Canadian Institutes of Health Research
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 14432, 2017
Mandates: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
M Le Gallo, AJ O'Hara, ML Rudd, ME Urick, NF Hansen, NJ O'Neil, ...
Nature genetics 44 (12), 1310-1315, 2012
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
International cooperation to enable the diagnosis of all rare genetic diseases
KM Boycott, A Rath, JX Chong, T Hartley, FS Alkuraya, G Baynam, ...
The American Journal of Human Genetics 100 (5), 695-705, 2017
Mandates: US National Institutes of Health, Canadian Institutes of Health Research …
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
PC Stirling, YA Chan, SW Minaker, MJ Aristizabal, I Barrett, ...
Genes & development 26 (2), 163-175, 2012
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae
S Ben-Aroya, C Coombes, T Kwok, KA O'Donnell, JD Boeke, P Hieter
Molecular cell 30 (2), 248-258, 2008
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Genome-wide profiling of yeast DNA: RNA hybrid prone sites with DRIP-chip
YA Chan, MJ Aristizabal, PYT Lu, Z Luo, A Hamza, MS Kobor, PC Stirling, ...
PLoS genetics 10 (4), e1004288, 2014
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing
KJ McManus, IJ Barrett, Y Nouhi, P Hieter
Proceedings of the National Academy of Sciences 106 (9), 3276-3281, 2009
Mandates: Canadian Institutes of Health Research
The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components
PC Stirling, MS Bloom, T Solanki-Patil, S Smith, P Sipahimalani, Z Li, ...
PLoS genetics 7 (4), e1002057, 2011
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Model organisms facilitate rare disease diagnosis and therapeutic research
MF Wangler, S Yamamoto, HT Chao, JE Posey, M Westerfield, ...
Genetics 207 (1), 9-27, 2017
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, Canadian …
MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome
JR Tyson, NJ O'Neil, M Jain, HE Olsen, P Hieter, TP Snutch
Genome research 28 (2), 266-274, 2018
Mandates: US National Institutes of Health, Canadian Cancer Society, Canadian …
Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation
V Measday, K Baetz, J Guzzo, K Yuen, T Kwok, B Sheikh, H Ding, R Ueta, ...
Proceedings of the National Academy of Sciences 102 (39), 13956-13961, 2005
Mandates: Genome Canada
From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II
H Braberg, H Jin, EA Moehle, YA Chan, S Wang, M Shales, JJ Benschop, ...
Cell 154 (4), 775-788, 2013
Mandates: US National Institutes of Health
Mechanisms of genome instability induced by RNA-processing defects
YA Chan, P Hieter, PC Stirling
Trends in Genetics 30 (6), 245-253, 2014
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development
DM van Pel, IJ Barrett, Y Shimizu, BV Sajesh, BJ Guppy, T Pfeifer, ...
PLoS genetics 9 (1), e1003254, 2013
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity
AP Bhavsar, NF Brown, J Stoepel, M Wiermer, DDO Martin, KJ Hsu, ...
PLoS pathogens 9 (7), e1003518, 2013
Mandates: US National Institutes of Health, National Health and Medical Research …
Complementation of yeast genes with human genes as an experimental platform for functional testing of human genetic variants
A Hamza, E Tammpere, M Kofoed, C Keong, J Chiang, G Giaever, ...
Genetics 201 (3), 1263-1274, 2015
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Glioblastoma Cells Containing Mutations in the Cohesin Component STAG2 Are Sensitive to PARP Inhibition
ML Bailey, NJ O'Neil, DM van Pel, DA Solomon, T Waldman, P Hieter
Molecular cancer therapeutics 13 (3), 724-732, 2014
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
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