The immunoreceptor TIGIT regulates antitumor and antiviral CD8+ T cell effector function RJ Johnston, L Comps-Agrar, J Hackney, X Yu, M Huseni, Y Yang, S Park, ... Cancer cell 26 (6), 923-937, 2014 | 1136 | 2014 |
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization D Maurel, L Comps-Agrar, C Brock, ML Rives, E Bourrier, MA Ayoub, ... Nature methods 5 (6), 561-567, 2008 | 569 | 2008 |
PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer SA Oh, DC Wu, J Cheung, A Navarro, H Xiong, R Cubas, K Totpal, H Chiu, ... Nature Cancer 1 (7), 681-691, 2020 | 319 | 2020 |
CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling AC Magalhaes, KD Holmes, LB Dale, L Comps-Agrar, D Lee, PN Yadav, ... Nature neuroscience 13 (5), 622-629, 2010 | 250 | 2010 |
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell–cell adhesion and signaling mechanism that requires cis-trans receptor clustering KF Stengel, K Harden-Bowles, X Yu, L Rouge, J Yin, L Comps-Agrar, ... Proceedings of the National Academy of Sciences 109 (14), 5399-5404, 2012 | 220 | 2012 |
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses KL Banta, X Xu, AS Chitre, A Au-Yeung, C Takahashi, WE O’Gorman, ... Immunity 55 (3), 512-526. e9, 2022 | 169 | 2022 |
Functional crosstalk between GPCRs: with or without oligomerization L Prezeau, ML Rives, L Comps-Agrar, D Maurel, J Kniazeff, JP Pin Current opinion in pharmacology 10 (1), 6-13, 2010 | 116 | 2010 |
Sustained brown fat stimulation and insulin sensitization by a humanized bispecific antibody agonist for fibroblast growth factor receptor 1/βKlotho complex G Kolumam, MZ Chen, R Tong, J Zavala-Solorio, L Kates, N van Bruggen, ... EBioMedicine 2 (7), 730-743, 2015 | 112 | 2015 |
The oligomeric state sets GABAB receptor signalling efficacy L Comps‐Agrar, J Kniazeff, L Nørskov‐Lauritsen, D Maurel, M Gassmann, ... The EMBO journal 30 (12), 2336-2349, 2011 | 108 | 2011 |
Methods of treating cancer using PD-1 axis binding antagonists and TIGIT inhibitors J Grogan, RJ Johnston, B Irving, J Hackney, X Yu, D Eaton, K Bowles, ... US Patent 9,873,740, 2018 | 98 | 2018 |
Antibody targeting of E3 ubiquitin ligases for receptor degradation H Marei, WTK Tsai, YS Kee, K Ruiz, J He, C Cox, T Sun, S Penikalapati, ... Nature 610 (7930), 182-189, 2022 | 87 | 2022 |
Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109 AE Fouts, L Comps-Agrar, KF Stengel, D Ellerman, AJ Schoeffler, ... Proceedings of the National Academy of Sciences 111 (22), 8209-8214, 2014 | 74 | 2014 |
G‐protein‐coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors JP Pin, L Comps‐Agrar, D Maurel, C Monnier, ML Rives, E Trinquet, ... The Journal of physiology 587 (22), 5337-5344, 2009 | 72 | 2009 |
Up-regulation of GABAB receptor signaling by constitutive assembly with the K+ channel tetramerization domain-containing protein 12 (KCTD12) K Ivankova, R Turecek, T Fritzius, R Seddik, L Prezeau, L Comps-Agrar, ... Journal of Biological Chemistry 288 (34), 24848-24856, 2013 | 42 | 2013 |
Stability of GABAB receptor oligomers revealed by dual TR‐FRET and drug‐induced cell surface targeting L Comps‐Agrar, J Kniazeff, C Brock, E Trinquet, JP Pin The FASEB Journal 26 (8), 3430-3439, 2012 | 39 | 2012 |
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies R Vij, Z Lin, N Chiang, JM Vernes, KM Storek, S Park, J Chan, YG Meng, ... Scientific Reports 8 (1), 7136, 2018 | 34 | 2018 |
Unliganded fibroblast growth factor receptor 1 forms density-independent dimers L Comps-Agrar, DR Dunshee, DL Eaton, J Sonoda Journal of Biological Chemistry 290 (40), 24166-24177, 2015 | 34 | 2015 |
Cell-surface protein–protein interaction analysis with time-resolved FRET and snap-tag technologies: application to G protein-coupled receptor oligomerization L Comps-Agrar, D Maurel, P Rondard, JP Pin, E Trinquet, L Prézeau Signal transduction protocols, 201-214, 2011 | 34 | 2011 |
Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD KM Storek, J Chan, R Vij, N Chiang, Z Lin, J Bevers III, CM Koth, ... Elife 8, e46258, 2019 | 33 | 2019 |
Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization M Cottet, L Albizu, L Comps-Agrar, E Trinquet, JP Pin, B Mouillac, ... Receptor Signal Transduction Protocols: Third Edition, 373-387, 2011 | 27 | 2011 |