Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 860 | 2018 |
Sensitive tumour detection and classification using plasma cell-free DNA methylomes SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ... Nature 563 (7732), 579-583, 2018 | 749 | 2018 |
Genomics-driven precision medicine for advanced pancreatic cancer: early results from the COMPASS trial KL Aung, SE Fischer, RE Denroche, GH Jang, A Dodd, S Creighton, ... Clinical Cancer Research 24 (6), 1344-1354, 2018 | 526 | 2018 |
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng, EF Figueroa, GM O’Kane, ... Nature genetics 52 (2), 231-240, 2020 | 490 | 2020 |
EGFR-Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes N Marcoux, SN Gettinger, G O’Kane, KC Arbour, JW Neal, H Husain, ... Journal of Clinical Oncology 37 (4), 278-285, 2019 | 378 | 2019 |
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 278 | 2022 |
Spatially confined sub-tumor microenvironments in pancreatic cancer BT Grünwald, A Devisme, G Andrieux, F Vyas, K Aliar, CW McCloskey, ... Cell 184 (22), 5577-5592. e18, 2021 | 258 | 2021 |
GATA6 expression distinguishes classical and basal-like subtypes in advanced pancreatic cancer GM O’Kane, BT Grünwald, GH Jang, M Masoomian, S Picardo, RC Grant, ... Clinical Cancer Research 26 (18), 4901-4910, 2020 | 249 | 2020 |
Integration of genomic and transcriptional features in pancreatic cancer reveals increased cell cycle progression in metastases AA Connor, RE Denroche, GH Jang, M Lemire, A Zhang, ... Cancer cell 35 (2), 267-282. e7, 2019 | 185 | 2019 |
Uncommon EGFR mutations in advanced non-small cell lung cancer GM O’kane, PA Bradbury, R Feld, NB Leighl, G Liu, KM Pisters, ... Lung Cancer 109, 137-144, 2017 | 159 | 2017 |
Altered gene expression along the glycolysis–cholesterol synthesis axis is associated with outcome in pancreatic cancer JM Karasinska, JT Topham, SE Kalloger, GH Jang, RE Denroche, ... Clinical Cancer Research 26 (1), 135-146, 2020 | 152 | 2020 |
A four-chemokine signature is associated with a T-cell–inflamed phenotype in primary and metastatic pancreatic cancer JM Romero, B Grünwald, GH Jang, PP Bavi, A Jhaveri, M Masoomian, ... Clinical Cancer Research 26 (8), 1997-2010, 2020 | 120 | 2020 |
A phase 2 trial of sunitinib in patients with progressive paraganglioma or pheochromocytoma: the SNIPP trial GM O’Kane, S Ezzat, AM Joshua, I Bourdeau, R Leibowitz-Amit, HJ Olney, ... British journal of cancer 120 (12), 1113-1119, 2019 | 116 | 2019 |
Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome SN Kalimuthu, GW Wilson, RC Grant, M Seto, G O’Kane, R Vajpeyi, ... Gut 69 (2), 317-328, 2020 | 107 | 2020 |
Genomic features and classification of homologous recombination deficient pancreatic ductal adenocarcinoma T Golan, GM O’Kane, RE Denroche, M Raitses-Gurevich, RC Grant, ... Gastroenterology 160 (6), 2119-2132. e9, 2021 | 106 | 2021 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 91 | |
Monitoring and management of immune‐related adverse events associated with programmed cell death protein‐1 axis inhibitors in lung cancer GM O’Kane, C Labbé, MK Doherty, K Young, H Albaba, NB Leighl The Oncologist 22 (1), 70-80, 2017 | 82 | 2017 |
A national stakeholder consensus study of challenges and priorities for clinical learning environments in postgraduate medical education C Kilty, A Wiese, C Bergin, P Flood, N Fu, M Horgan, A Higgins, B Maher, ... BMC Medical Education 17, 1-9, 2017 | 77 | 2017 |
Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma RC Grant, R Denroche, GH Jang, KM Nowak, A Zhang, A Borgida, ... Gut 70 (10), 1894-1903, 2021 | 68 | 2021 |
Third-generation tyrosine kinase inhibitors targeting epidermal growth factor receptor mutations in non-small cell lung cancer TA Barnes, GM O’Kane, MD Vincent, NB Leighl Frontiers in oncology 7, 113, 2017 | 64 | 2017 |