Articles with public access mandates - Randall W. KingLearn more
Available somewhere: 28
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
BH Lee, MJ Lee, S Park, DC Oh, S Elsasser, PC Chen, C Gartner, ...
Nature 467 (7312), 179-184, 2010
Mandates: US National Institutes of Health
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response
B Adamson, A Smogorzewska, FD Sigoillot, RW King, SJ Elledge
Nature cell biology 14 (3), 318-328, 2012
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
X Zeng, F Sigoillot, S Gaur, S Choi, KL Pfaff, DC Oh, N Hathaway, ...
Cancer cell 18 (4), 382-395, 2010
Mandates: US National Institutes of Health
Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes
MJ Lee, BH Lee, J Hanna, RW King, D Finley
Molecular & Cellular Proteomics 10 (5), 2011
Mandates: US National Institutes of Health
Substrate degradation by the proteasome: a single-molecule kinetic analysis
Y Lu, B Lee, RW King, D Finley, MW Kirschner
Science 348 (6231), 1250834, 2015
Mandates: US National Institutes of Health
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C
KL Sackton, N Dimova, X Zeng, W Tian, M Zhang, TB Sackton, J Meaders, ...
Nature 514 (7524), 646-649, 2014
Mandates: US Department of Energy, US National Institutes of Health, Howard Hughes …
USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites
BH Lee, Y Lu, MA Prado, Y Shi, G Tian, S Sun, S Elsasser, SP Gygi, ...
Nature 532 (7599), 398-401, 2016
Mandates: US National Institutes of Health
A non-genetic route to aneuploidy in human cancers
M Krajcovic, NB Johnson, Q Sun, G Normand, N Hoover, E Yao, ...
Nature cell biology 13 (3), 324-330, 2011
Mandates: US National Institutes of Health
A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens
FD Sigoillot, S Lyman, JF Huckins, B Adamson, E Chung, B Quattrochi, ...
Nature methods 9 (4), 363-366, 2012
Mandates: US National Institutes of Health
APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1
NV Dimova, NA Hathaway, BH Lee, DS Kirkpatrick, ML Berkowitz, ...
Nature cell biology 14 (2), 168-176, 2012
Mandates: US National Institutes of Health
When 2+ 2= 5: the origins and fates of aneuploid and tetraploid cells
RW King
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1786 (1), 4-14, 2008
Mandates: US National Institutes of Health
Vigilance and validation: Keys to success in RNAi screening
FD Sigoillot, RW King
ACS chemical biology 6 (1), 47-60, 2011
Mandates: US National Institutes of Health
High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors
CV Miduturu, X Deng, N Kwiatkowski, W Yang, L Brault, ...
Chemistry & biology 18 (7), 868-879, 2011
Mandates: US National Institutes of Health, Canadian Institutes of Health Research …
An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons
M Boselli, BH Lee, J Robert, MA Prado, SW Min, C Cheng, MC Silva, ...
Journal of Biological Chemistry 292 (47), 19209-19225, 2017
Mandates: US National Institutes of Health
An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination
X Zeng, RW King
Nature chemical biology 8 (4), 383-392, 2012
Mandates: US National Institutes of Health
A randomized, placebo-controlled trial of roflumilast. Effect on proline-glycine-proline and neutrophilic inflammation in chronic obstructive pulmonary disease
JM Wells, PL Jackson, L Viera, SP Bhatt, J Gautney, G Handley, RW King, ...
American journal of respiratory and critical care medicine 192 (8), 934-942, 2015
Mandates: US National Institutes of Health
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function
J De Lange, A Faramarz, AB Oostra, RX De Menezes, IH Van Der Meulen, ...
Nature communications 6 (1), 8399, 2015
Mandates: US National Institutes of Health, Dutch Cancer Society, Human Frontier …
The G2/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20
HJ Lim, NV Dimova, MKM Tan, FD Sigoillot, RW King, Y Shi
Molecular and cellular biology 33 (21), 4166-4180, 2013
Mandates: US National Institutes of Health, A*Star, Singapore
Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells
S Lub, A Maes, K Maes, K De Veirman, E De Bruyne, E Menu, K Fostier, ...
Oncotarget 7 (4), 4062, 2016
Mandates: US National Institutes of Health, Research Foundation (Flanders)
A High‐Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14
BH Lee, D Finley, RW King
Current protocols in chemical biology 4 (4), 311-330, 2012
Mandates: US National Institutes of Health
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