Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands U Sahin, G Weskamp, K Kelly, HM Zhou, S Higashiyama, J Peschon, ... The Journal of cell biology 164 (5), 769-779, 2004 | 1221 | 2004 |
Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins U Sahin, O Ferhi, M Jeanne, S Benhenda, C Berthier, F Jollivet, ... Journal of Cell Biology 204 (6), 931-945, 2014 | 242 | 2014 |
Sumoylation on its 25th anniversary: mechanisms, pathology, and emerging concepts AB Celen, U Sahin The FEBS journal 287 (15), 3110-3140, 2020 | 177 | 2020 |
Essential role for ADAM19 in cardiovascular morphogenesis HM Zhou, G Weskamp, V Chesneau, U Sahin, A Vortkamp, K Horiuchi, ... Molecular and cellular biology 24 (1), 96-104, 2004 | 169 | 2004 |
Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17 U Sahin, CP Blobel FEBS letters 581 (1), 41-44, 2007 | 151 | 2007 |
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells H El Hajj, Z Dassouki, C Berthier, E Raffoux, L Ades, O Legrand, R Hleihel, ... Blood, The Journal of the American Society of Hematology 125 (22), 3447-3454, 2015 | 134 | 2015 |
PML nuclear bodies: assembly and oxidative stress-sensitive sumoylation U Sahin, H de Thé, V Lallemand-Breitenbach Nucleus 5 (6), 499-507, 2014 | 91 | 2014 |
ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation Z Dassouki, U Sahin, H El Hajj, F Jollivet, Y Kfoury, ... Blood, The Journal of the American Society of Hematology 125 (3), 474-482, 2015 | 79 | 2015 |
PML nuclear bodies: regulation, function and therapeutic perspectives U Sahin, V Lallemand‐Breitenbach, H de Thé The Journal of pathology 234 (3), 289-291, 2014 | 71 | 2014 |
A sensitive method to monitor ectodomain shedding of ligands of the epidermal growth factor receptor U Sahin, G Weskamp, Y Zheng, V Chesneau, K Horiuchi, CP Blobel Methods Mol Biol 327, 99-113, 2006 | 65 | 2006 |
Interferon controls SUMO availability via the Lin28 and let-7 axis to impede virus replication U Sahin, O Ferhi, X Carnec, A Zamborlini, L Peres, F Jollivet, ... Nature communications 5 (1), 4187, 2014 | 53 | 2014 |
Sumoylation of human argonaute 2 at lysine-402 regulates its stability U Sahin, P Lapaquette, A Andrieux, G Faure, A Dejean PloS one 9 (7), e102957, 2014 | 48 | 2014 |
Sumoylation in Physiology, Pathology and Therapy U Sahin, H de Thé, V Lallemand-Breitenbach Cells 11 (5), 814, 2022 | 33 | 2022 |
Characterization of the catalytic properties of the membrane-anchored metalloproteinase ADAM9 in cell-based assays T Maretzky, S Swendeman, E Mogollon, G Weskamp, U Sahin, K Reiss, ... Biochemical Journal 474 (9), 1467-1479, 2017 | 22 | 2017 |
Detection of protein SUMOylation in situ by proximity ligation assays U Sahin, F Jollivet, C Berthier, V Lallemand-Breitenbach Methods Mol Biol 1475, 139-150, 2016 | 15 | 2016 |
A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells S Auvin, H Öztürk, YT Abaci, G Mautino, F Meyer-Losic, F Jollivet, T Bashir, ... Life Science Alliance 2 (4), e201800213, 2019 | 13 | 2019 |
Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding T Ergünay, Ö Ayhan, AB Celen, P Georgiadou, E Pekbilir, YT Abaci, ... Life Science Alliance 5 (4), 2022 | 8 | 2022 |
A novel homozygous loss-of-function variant in SOD1 causing progressive spastic tetraplegia and axial hypotonia A Çakar, E Pekbilir, S Ceylaner, H Durmuş, E Battaloğlu, U Şahin, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 24 (5-6), 535-538, 2023 | 4 | 2023 |
Human immunodeficiency virus type 1 impairs sumoylation B Mete, E Pekbilir, BN Bilge, P Georgiadou, E Çelik, T Sutlu, F Tabak, ... Life Science Alliance 5 (6), 2022 | 3 | 2022 |
Umut Şahin: SUMOylation in health and disease U Şahin Life Science Alliance 5 (6), 2022 | | 2022 |