Articles with public access mandates - Roisin LoftusLearn more
Not available anywhere: 2
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
S Viel, A Marçais, FSF Guimaraes, R Loftus, J Rabilloud, M Grau, ...
Science signaling 9 (415), ra19-ra19, 2016
Mandates: National Health and Medical Research Council, Australia, National Institute …
Metabolic reprogramming supports IFN-γ production by CD56bright NK cells
SE Keating, V Zaiatz-Bittencourt, RM Loftus, C Keane, K Brennan, ...
The Journal of Immunology 196 (6), 2552-2560, 2016
Mandates: Science Foundation Ireland, European Commission
Available somewhere: 8
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ...
Nature immunology 19 (12), 1330-1340, 2018
Mandates: US National Institutes of Health, European Commission
Immunometabolism: cellular metabolism turns immune regulator
RM Loftus, DK Finlay
Journal of Biological Chemistry 291 (1), 1-10, 2016
Mandates: Science Foundation Ireland, European Commission
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function
RP Donnelly, RM Loftus, SE Keating, KT Liou, CA Biron, CM Gardiner, ...
The Journal of Immunology 193 (9), 4477-4484, 2014
Mandates: US National Institutes of Health, Health Research Board, Ireland, Science …
Srebp-controlled glucose metabolism is essential for NK cell functional responses
N Assmann, KL O'Brien, RP Donnelly, L Dyck, V Zaiatz-Bittencourt, ...
Nature immunology 18 (11), 1197-1206, 2017
Mandates: German Research Foundation, Science Foundation Ireland
Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
RM Loftus, N Assmann, N Kedia-Mehta, KL O’Brien, A Garcia, C Gillespie, ...
Nature communications 9 (1), 2341, 2018
Mandates: German Research Foundation, Science Foundation Ireland, Wellcome Trust
Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
N Lopes, C McIntyre, S Martin, M Raverdeau, N Sumaria, AC Kohlgruber, ...
Nature immunology 22 (2), 179-192, 2021
Mandates: US National Institutes of Health, European Molecular Biology Laboratory …
Obesity reduces mTORC1 activity in mucosal-associated invariant T cells, driving defective metabolic and functional responses
A O’Brien, RM Loftus, MM Pisarska, LM Tobin, R Bergin, NAW Wood, ...
The Journal of Immunology 202 (12), 3404-3411, 2019
Mandates: Health Research Board, Ireland, Science Foundation Ireland, UK Medical …
Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function
L Dyck, H Prendeville, M Raverdeau, MM Wilk, RM Loftus, A Douglas, ...
Journal of Experimental Medicine 219 (3), 2022
Mandates: US National Institutes of Health, Science Foundation Ireland, European …
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