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Kannan Sankar
Kannan Sankar
Bioinformatics Data Scientist at Novartis Institutes for Biomedical Research (NIBR)
Verified email at novartis.com - Homepage
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Year
AggScore: prediction of aggregation‐prone regions in proteins based on the distribution of surface patches
K Sankar, SR Krystek Jr, SM Carl, T Day, JKX Maier
Proteins: Structure, Function, and Bioinformatics 86 (11), 1147-1156, 2018
992018
Molecular determinants of cadherin ideal bond formation: Conformation-dependent unbinding on a multidimensional landscape
K Manibog, K Sankar, SA Kim, Y Zhang, RL Jernigan, S Sivasankar
Proceedings of the National Academy of Sciences 113 (39), E5711-E5720, 2016
502016
Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method
K Sankar, KH Hoi, Y Yin, P Ramachandran, N Andersen, A Hilderbrand, ...
MAbs 10 (8), 1281-1290, 2018
452018
Knowledge-based entropies improve the identification of native protein structures
K Sankar, K Jia, RL Jernigan
Proceedings of the National Academy of Sciences 114 (11), 2928-2933, 2017
332017
Comparisons of protein dynamics from experimental structure ensembles, molecular dynamics ensembles, and coarse-grained elastic network models
K Sankar, SK Mishra, RL Jernigan
The journal of physical chemistry B 122 (21), 5409-5417, 2018
292018
Directional force originating from ATP hydrolysis drives the GroEL conformational change
J Liu, K Sankar, Y Wang, K Jia, RL Jernigan
Biophysical journal 112 (8), 1561-1570, 2017
232017
Structure and function of LCI1: a plasma membrane CO2 channel in the Chlamydomonas CO2 concentrating mechanism
A Kono, TH Chou, A Radhakrishnan, JR Bolla, K Sankar, S Shome, ...
The Plant Journal 102 (6), 1107-1126, 2020
222020
Distributions of experimental protein structures on coarse-grained free energy landscapes
K Sankar, J Liu, Y Wang, RL Jernigan
The Journal of chemical physics 143 (24), 2015
222015
The use of experimental structures to model protein dynamics
AR Katebi, K Sankar, K Jia, RL Jernigan
Molecular Modeling of Proteins, 213-236, 2015
202015
Structural differences and differential expression among rhabdomeric opsins reveal functional change after gene duplication in the bay scallop, Argopecten irradians (Pectinidae)
AJ Porath-Krause, AN Pairett, D Faggionato, BS Birla, K Sankar, JM Serb
BMC Evolutionary Biology 16, 1-15, 2016
192016
DOR–a database of olfactory receptors–integrated repository for sequence and secondary structural information of olfactory receptors in selected eukaryotic genomes
B Nagarathnam, SD Karpe, K Harini, K Sankar, M Iftekhar, D Rajesh, ...
Bioinformatics and Biology insights 8, BBI. S14858, 2014
182014
A descriptor set for quantitative structure‐property relationship prediction in biologics
K Sankar, K Trainor, LL Blazer, JJ Adams, SS Sidhu, T Day, E Meiering, ...
Molecular Informatics 41 (9), 2100240, 2022
152022
Dynamics of heavy chain junctional length biases in antibody repertoires
K Sankar, KH Hoi, I Hötzel
Communications biology 3 (1), 207, 2020
152020
Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences
J Coffman, B Marques, R Orozco, M Aswath, H Mohammad, ...
Biotechnology and Bioengineering 117 (7), 2100-2115, 2020
142020
Altered dynamics upon oligomerization corresponds to key functional sites
SK Mishra, K Sankar, RL Jernigan
Proteins: Structure, Function, and Bioinformatics 85 (8), 1422-1434, 2017
112017
Structural interface parameters are discriminatory in recognising near-native poses of protein-protein interactions
S Malhotra, K Sankar, R Sowdhamini
PLoS One 9 (2), e80255, 2014
92014
Insights from the analysis of conserved motifs and permitted amino acid exchanges in the human, the fly and the worm GPCR clusters
B Nagarathnam, S Kannan, V Dharnidharka, V Balakrishnan, G Archunan, ...
Bioinformation 7 (1), 15, 2011
62011
An analysis of conformational changes upon RNA-protein binding
K Sankar, RR Walia, CM Mann, RL Jernigan, VG Honavar, D Dobbs
Proceedings of the 5th ACM Conference on Bioinformatics, Computational …, 2014
52014
Residue conservation and dimer-interface analysis of olfactory receptor molecular models
K Harini, S Kannan, W Nemoto, K Fukui, R Sowdhamini
Journal of Molecular Biochemistry 1 (3), 2012
52012
TM-MOTIF: an alignment viewer to annotate predicted transmembrane helices and conserved motifs in aligned set of sequences
B Nagarathnam, K Sankar, V Dharnidharka, V Balakrishnan, G Archunan, ...
Bioinformation 7 (5), 214, 2011
52011
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