| Physiological‐based pharmacokinetic modeling trends in pharmaceutical drug development over the last 20‐years; in‐depth analysis of applications, organizations, and platforms E El‐Khateeb, S Burkhill, S Murby, H Amirat, A Rostami‐Hodjegan, ... Biopharmaceutics & Drug Disposition 42 (4), 107-117, 2021 | 89 | 2021 |
| Non-uniformity of changes in drug-metabolizing enzymes and transporters in liver cirrhosis: implications for drug dosage adjustment E El-Khateeb, B Achour, ZM Al-Majdoub, J Barber, A Rostami-Hodjegan Molecular Pharmaceutics 18 (9), 3563-3577, 2021 | 43 | 2021 |
| time to revisit Child‐Pugh score as the basis for predicting drug clearance in hepatic impairment E El‐Khateeb, AS Darwich, B Achour, V Athwal, A Rostami‐Hodjegan Alimentary Pharmacology & Therapeutics 54 (4), 388-401, 2021 | 35 | 2021 |
| Effects of three different fibrates on intrahepatic cholestasis experimentally induced in rats A El-Sisi, S Hegazy, E El-Khateeb PPAR research 2013 (1), 781348, 2013 | 35 | 2013 |
| Pharmacokinetics under the COVID‐19 storm V Pilla Reddy, E El‐Khateeb, H Jo, N Giovino, E Lythgoe, S Sharma, ... British Journal of Clinical Pharmacology 89 (1), 158-186, 2020 | 28 | 2020 |
| Mass Spectrometry‐Based Abundance Atlas of ABC Transporters in Human Liver, Gut, Kidney, Brain, and Skin JB Zubida M. Al‐Majdoub, Brahim Achour, Narciso Couto, Martyn Howard ... FEBS letters, 2020 | 25 | 2020 |
| Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: applications in translational pharmacology and recommendations for best practice E El-Khateeb, AM Vasilogianni, S Alrubia, ZM Al-Majdoub, N Couto, ... Pharmacology & Therapeutics 203, 107397, 2019 | 23 | 2019 |
| Proteomic quantification of changes in abundance of drug-metabolizing enzymes and drug transporters in human liver cirrhosis: different methods, similar outcomes E El-Khateeb, ZM Al-Majdoub, A Rostami-Hodjegan, J Barber, B Achour Drug Metabolism and Disposition 49 (8), 610-618, 2021 | 19 | 2021 |
| Scaling factors for clearance in adult liver cirrhosis E El-Khateeb, B Achour, D Scotcher, ZM Al-Majdoub, V Athwal, J Barber, ... Drug Metabolism and Disposition 48 (12), 1271-1282, 2020 | 19 | 2020 |
| Bioanalytical strategies in drug discovery and development A Thakur, Z Tan, T Kameyama, E El-Khateeb, S Nagpal, S Malone, ... Drug Metabolism Reviews 53 (3), 434-458, 2021 | 10 | 2021 |
| Proteomic quantification of perturbation to pharmacokinetic target proteins in liver disease AM Vasilogianni, E El-Khateeb, ZM Al-Majdoub, S Alrubia, ... Journal of Proteomics 263, 104601, 2022 | 9 | 2022 |
| A randomized placebo-controlled, double-blind study to investigate the effect of a high oral loading dose of cholecalciferol in non-alcoholic fatty liver disease patients, new … SJ Alarfaj, MM Bahaa, HA Yassin, E El-Khateeb, FA Kotkata, ... European Review for Medical & Pharmacological Sciences 27 (16), 2023 | 5 | 2023 |
| A family of QconCATs (Quantification conCATemers) for the quantification of human pharmacological target proteins AM Vasilogianni, E El-Khateeb, B Achour, S Alrubia, A Rostami-Hodjegan, ... Journal of Proteomics 261, 104572, 2022 | 5 | 2022 |
| Evaluating the safety and efficacy of the leukotriene receptor antagonist montelukast as adjuvant therapy in obese patients with type 2 diabetes mellitus: A double-blind … E El-Khateeb, EI El-Berri, EM Mosalam, MZ Nooh, S Abdelsattar, ... Frontiers in Pharmacology 14, 1153653, 2023 | 4 | 2023 |
| The potential therapeutic effect of metformin in type 2 diabetic patients with severe COVID-19. HM Al-Kuraishy, AI Al-Gareeb, AA El Kholy, E El-Khateeb, A Alexiou, ... European Review for Medical & Pharmacological Sciences 27 (23), 2023 | 2 | 2023 |
| Using Prior Knowledge on Systems Through PBPK to Gain Further Insight into Routine Clinical Data on Trough Concentrations: The Case of Tacrolimus in Chronic Kidney Disease E El-Khateeb, R Chinnadurai, J Al Qassabi, D Scotcher, AS Darwich, ... Therapeutic Drug Monitoring, 10.1097, 2022 | 1 | 2022 |
| A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator L Curry, S Alrubia, FY Bois, R Clayton, E El-Khateeb, TN Johnson, ... CPT Pharmacometrics Syst Pharmacol, 1-19, 2024 | | 2024 |
| Correlation between depression scores and serum NF‐ĸB/NLRP3 axis, biotinidase, and HMGB1 after treatment with isotretinoin in patients with acne vulgaris AY Binsaleh, LS Ali, MM Bahaa, TA Elmasry, WA Negm, AO Hamouda, ... Journal of Cosmetic Dermatology, 1-9, 2024 | | 2024 |
| A Randomized Controlled Trial Comparing Tacrolimus versus Hydrocortisone for the Treatment of Atopic Dermatitis in Children: New Perspectives on Interferon Gamma-Induced … M Bahaa, AY Binsaleh, TA Elmasry, EI Elberri, FA Kotkata, E El-Khateeb, ... Frontiers in Medicine 11, 1399305, 2024 | | 2024 |
| Complementarity of two proteomic data analysis tools in the identification of drug-metabolising enzymes and transporters in human liver AM Vasilogianni, S Alrubia, E El-Khateeb, ZM Al-Majdoub, N Couto, ... Molecular Omics 20 (2), 115-127, 2024 | | 2024 |
Amin Rostami-HodjeganProfessor of Systems Pharmacology, University of Manchester, UKVerified email at manchester.ac.uk
