High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis: mechanisms and a phase I/IIa study K Polireddy, R Dong, G Reed, J Yu, P Chen, S Williamson, PC Violet, ... Scientific reports 7 (1), 17188, 2017 | 146 | 2017 |
Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis E Ma, P Chen, HM Wilkins, T Wang, RH Swerdlow, Q Chen Free Radical Biology and Medicine 113, 36-47, 2017 | 75 | 2017 |
An RNA-binding protein, Hu-antigen R, in pancreatic cancer epithelial to mesenchymal transition, metastasis, and cancer stem cells R Dong, P Chen, K Polireddy, X Wu, T Wang, R Ramesh, DA Dixon, L Xu, ... Molecular cancer therapeutics 19 (11), 2267-2277, 2020 | 46 | 2020 |
The unpaved journey of vitamin C in cancer treatment Q Chen, K Polireddy, P Chen, R Dong Canadian journal of physiology and pharmacology 93 (12), 1055-1063, 2015 | 45 | 2015 |
Targeting epithelial-mesenchymal transition for identification of inhibitors for pancreatic cancer cell invasion and tumor spheres formation K Polireddy, R Dong, PR McDonald, T Wang, B Luke, P Chen, M Broward, ... PLoS One 11 (10), e0164811, 2016 | 29 | 2016 |
Pharmacokinetic evaluation of intravenous vitamin C: a classic pharmacokinetic study P Chen, G Reed, J Jiang, Y Wang, J Sunega, R Dong, Y Ma, A Esparham, ... Clinical pharmacokinetics 61 (9), 1237-1249, 2022 | 19 | 2022 |
Pharmacological ascorbate induces ‘BRCAness’ and enhances the effects of Poly (ADP‑Ribose) polymerase inhibitors against BRCA1/2 wild‑type ovarian cancer Y Ma, P Chen, JA Drisko, D Khabele, AK Godwin, Q Chen Oncology Letters 19 (4), 2629-2638, 2020 | 19 | 2020 |
Inhibition of pancreatic cancer stem cells by Rauwolfia vomitoria extract R Dong, P Chen, Q Chen Oncology reports 40 (6), 3144-3154, 2018 | 19 | 2018 |
Extract of the medicinal plant Pao Pereira inhibits pancreatic cancer stem-like cell in vitro and in vivo R Dong, P Chen, Q Chen Integrative Cancer Therapies 17 (4), 1204-1215, 2018 | 18 | 2018 |
Extracts of the Medicinal Plants Pao Pereira and Rauwolfia vomitoria Inhibit Ovarian Cancer Stem Cells In Vitro P Chen, R Dong, Q Chen Integrative Cancer Therapies 21, 15347354221123019, 2022 | 3 | 2022 |
High Dose Intravenous Vitamin C as Adjunctive Therapy for COVID-19 Patients with Cancer: Two Cases G Guo, Q Chen, G Luo, Z Meng, P Lei, P Chen, JA Drisko Life 12 (3), 335, 2022 | 2 | 2022 |
Effects of Different Tea Products on the Growth of Cancer Cells P Chen, Q Chen EC Nutrition 14, 01-13, 2019 | 2 | 2019 |
Novel compound C150 inhibits pancreatic cancer through induction of ER stress and proteosome assembly T Wang, P Chen, S Weir, M Baltezor, FJ Schoenen, Q Chen Frontiers in Oncology 12, 870473, 2022 | 1 | 2022 |
IV vitamin C with chemotherapy for cisplatin ineligible bladder cancer patients (CI-MIBC) first-stage analysis NCT04046094. RA Parikh, JA Taylor, Q Chen, BL Woolbright, P Chen, ... Journal of Clinical Oncology 40 (16_suppl), e16540-e16540, 2022 | 1 | 2022 |
Novel compound C150 inhibits pancreatic cancer cell epithelial-to-Mesenchymal transition and tumor growth in mice T Wang, P Chen, R Dong, S Weir, M Baltezor, FJ Schoenen, Q Chen Frontiers in Oncology 11, 773350, 2021 | 1 | 2021 |
An RNA binding protein, HuR, in pancreatic cancer EMT, metastasis, and CSC R Dong, K Polireddy, X Wu, P Chen, T Wang, D Dixon, L Xu, Q Chen The FASEB Journal 33 (S1), 674.10-674.10, 2019 | 1 | 2019 |
Extracts of the medicinal plants Pao Pereira and Rauwolfia vomitoria inhibit ovarian cancer stem cells in vitro Q Chen, R Dong, P Chen The FASEB Journal 33 (S1), 816.2-816.2, 2019 | 1 | 2019 |
The redox metabolome of humans receiving supraphysiological doses of intravenous vitamin C P Thavrin, J Choi, P Chen, Q Chen, J Drisko, JF Stevens Free Radical Biology and Medicine 201, 20, 2023 | | 2023 |
LBA01-09 INTERIM ANALYSIS NCT04046094: IV VITAMIN C WITH CHEMOTHERAPY FOR CISPLATIN INELIGIBLE BLADDER CANCER PATIENTS (CI-MIBC) J Taylor, R Parikh, Q Chen, B Woolbright, P Chen, E Wulff-Burchfield, ... The Journal of Urology 207 (Supplement 5), e1039, 2022 | | 2022 |
A Pharmacokinetic Study of High‐Dose Intravenous Vitamin C in Healthy Volunteers and Oncological Patients P Chen, Y Ma, G Reed, Y Jiang, M Levine, J Drisko, Q Chen The FASEB Journal 35, 2021 | | 2021 |