| Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve N Uemura, H Yagi, MT Uemura, Y Hatanaka, H Yamakado, R Takahashi Molecular neurodegeneration 13, 1-11, 2018 | 268 | 2018 |
| Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases S Ansai, T Sakuma, T Yamamoto, H Ariga, N Uemura, R Takahashi, ... Genetics 193 (3), 739-749, 2013 | 140 | 2013 |
| Cell-to-cell transmission of tau and α-synuclein N Uemura, MT Uemura, KC Luk, VMY Lee, JQ Trojanowski Trends in molecular medicine 26 (10), 936-952, 2020 | 113 | 2020 |
| α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson’s disease model T Taguchi, M Ikuno, M Hondo, LK Parajuli, K Taguchi, J Ueda, ... Brain 143 (1), 249-265, 2020 | 90 | 2020 |
| Design, evaluation, and screening methods for efficient targeted mutagenesis with transcription activator‐like effector nucleases in medaka S Ansai, K Inohaya, Y Yoshiura, M Schartl, N Uemura, R Takahashi, ... Development, growth & differentiation 56 (1), 98-107, 2014 | 89 | 2014 |
| ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons H Matsui, F Sato, S Sato, M Koike, Y Taruno, S Saiki, M Funayama, H Ito, ... FEBS letters 587 (9), 1316-1325, 2013 | 79 | 2013 |
| Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein N Uemura, M Koike, S Ansai, M Kinoshita, T Ishikawa-Fujiwara, H Matsui, ... PLoS genetics 11 (4), e1005065, 2015 | 77 | 2015 |
| Pathological endogenous α-synuclein accumulation in oligodendrocyte precursor cells potentially induces inclusions in multiple system atrophy S Kaji, T Maki, H Kinoshita, N Uemura, T Ayaki, Y Kawamoto, T Furuta, ... Stem cell reports 10 (2), 356-365, 2018 | 73 | 2018 |
| ATP maintenance via two types of ATP regulators mitigates pathological phenotypes in mouse models of Parkinson's disease M Nakano, H Imamura, N Sasaoka, M Yamamoto, N Uemura, T Shudo, ... EBioMedicine 22, 225-241, 2017 | 66 | 2017 |
| PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates H Matsui, R Gavinio, T Asano, N Uemura, H Ito, Y Taniguchi, Y Kobayashi, ... Human molecular genetics 22 (12), 2423-2434, 2013 | 58 | 2013 |
| Slow progressive accumulation of oligodendroglial alpha-synuclein (α-syn) pathology in synthetic α-syn fibril-induced mouse models of synucleinopathy N Uemura, MT Uemura, A Lo, F Bassil, B Zhang, KC Luk, VMY Lee, ... Journal of Neuropathology & Experimental Neurology 78 (10), 877-890, 2019 | 56 | 2019 |
| GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson’s disease M Ikuno, H Yamakado, H Akiyama, LK Parajuli, K Taguchi, J Hara, ... Human molecular genetics 28 (11), 1894-1904, 2019 | 48 | 2019 |
| α‐Synuclein Spread from Olfactory Bulb Causes Hyposmia, Anxiety, and Memory Loss in BAC‐SNCA Mice N Uemura, J Ueda, T Yoshihara, M Ikuno, MT Uemura, H Yamakado, ... Movement Disorders 36 (9), 2036-2047, 2021 | 44 | 2021 |
| Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro NP Marotta, J Ara, N Uemura, MG Lougee, ES Meymand, B Zhang, ... Acta neuropathologica communications 9, 1-18, 2021 | 40 | 2021 |
| The first Japanese case of leukodystrophy with ovarian failure arising from novel compound heterozygous AARS2 mutations M Hamatani, N Jingami, Y Tsurusaki, S Shimada, K Shimojima, ... Journal of human genetics 61 (10), 899-902, 2016 | 37 | 2016 |
| Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease MT Uemura, JL Robinson, KAQ Cousins, TF Tropea, DC Kargilis, ... Acta Neuropathologica 143 (1), 15-31, 2022 | 33 | 2022 |
| Glucocerebrosidases catalyze a transgalactosylation reaction that yields a newly-identified brain sterol metabolite, galactosylated cholesterol H Akiyama, M Ide, Y Nagatsuka, T Sayano, E Nakanishi, N Uemura, ... Journal of Biological Chemistry 295 (16), 5257-5277, 2020 | 29 | 2020 |
| Limited spread of pathology within the brainstem of α-synuclein BAC transgenic mice inoculated with preformed fibrils into the gastrointestinal tract N Uemura, H Yagi, MT Uemura, H Yamakado, R Takahashi Neuroscience letters 716, 134651, 2020 | 28 | 2020 |
| Perampanel Inhibits α‐Synuclein Transmission in Parkinson's Disease Models J Ueda, N Uemura, M Sawamura, T Taguchi, M Ikuno, S Kaji, Y Taruno, ... Movement Disorders 36 (7), 1554-1564, 2021 | 25 | 2021 |
| Exploring the pathogenetic mechanisms underlying Parkinson's disease in medaka fish H Matsui, N Uemura, H Yamakado, S Takeda, R Takahashi Journal of Parkinson's Disease 4 (2), 301-310, 2014 | 24 | 2014 |
