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High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response H Gao, JM Korn, S Ferretti, JE Monahan, Y Wang, M Singh, C Zhang, ... Nature medicine 21 (11), 1318-1325, 2015 | 1377 | 2015 |
arrayQualityMetrics—a bioconductor package for quality assessment of microarray data A Kauffmann, R Gentleman, W Huber Bioinformatics 25 (3), 415-416, 2009 | 1048 | 2009 |
Project DRIVE: a compendium of cancer dependencies and synthetic lethal relationships uncovered by large-scale, deep RNAi screening ER McDonald, A De Weck, MR Schlabach, E Billy, KJ Mavrakis, ... Cell 170 (3), 577-592. e10, 2017 | 631 | 2017 |
Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials C Fritsch, A Huang, C Chatenay-Rivauday, C Schnell, A Reddy, M Liu, ... Molecular cancer therapeutics 13 (5), 1117-1129, 2014 | 497 | 2014 |
Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity F Chibon, P Lagarde, S Salas, G Pérot, V Brouste, F Tirode, C Lucchesi, ... Nature medicine 16 (7), 781-787, 2010 | 473 | 2010 |
Pharmacological and genomic profiling identifies NF-κB–targeted treatment strategies for mantle cell lymphoma R Rahal, M Frick, R Romero, JM Korn, R Kridel, F Chun Chan, B Meissner, ... Nature medicine 20 (1), 87-92, 2014 | 403 | 2014 |
CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions DM Munoz, PJ Cassiani, L Li, E Billy, JM Korn, MD Jones, J Golji, ... Cancer discovery 6 (8), 900-913, 2016 | 383 | 2016 |
FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor V Guagnano, A Kauffmann, S Wöhrle, C Stamm, M Ito, L Barys, A Pornon, ... Cancer discovery 2 (12), 1118-1133, 2012 | 357 | 2012 |
Pharmacogenomic agreement between two cancer cell line data sets Cancer Cell Line Encyclopedia Consortium, ... Nature 528 (7580), 84-87, 2015 | 290 | 2015 |
High expression of DNA repair pathways is associated with metastasis in melanoma patients A Kauffmann, F Rosselli, V Lazar, V Winnepenninckx, A Mansuet-Lupo, ... Oncogene 27 (5), 565-573, 2008 | 279 | 2008 |
Apoptosis regulation in tetraploid cancer cells M Castedo, A Coquelle, S Vivet, I Vitale, A Kauffmann, P Dessen, ... The EMBO journal 25 (11), 2584-2595, 2006 | 241 | 2006 |
Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach H Raslova, A Kauffmann, D Sekkaï, H Ripoche, F Larbret, T Robert, ... Blood 109 (8), 3225-3234, 2007 | 146 | 2007 |
Mitotic checkpoints and chromosome instability are strong predictors of clinical outcome in gastrointestinal stromal tumors P Lagarde, G Pérot, A Kauffmann, C Brulard, V Dapremont, I Hostein, ... Clinical cancer research 18 (3), 826-838, 2012 | 145 | 2012 |
Characterization of the mechanism of action of the pan class I PI3K inhibitor NVP-BKM120 across a broad range of concentrations SM Brachmann, J Kleylein-Sohn, S Gaulis, A Kauffmann, MJJ Blommers, ... Molecular cancer therapeutics 11 (8), 1747-1757, 2012 | 143 | 2012 |
Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancers PD Garcia, JL Langowski, Y Wang, M Chen, J Castillo, C Fanton, M Ison, ... Clinical cancer research 20 (7), 1834-1845, 2014 | 134 | 2014 |
Microarray data quality control improves the detection of differentially expressed genes A Kauffmann, W Huber Genomics 95 (3), 138-142, 2010 | 123 | 2010 |
Importing arrayexpress datasets into r/bioconductor A Kauffmann, TF Rayner, H Parkinson, M Kapushesky, M Lukk, A Brazma, ... Bioinformatics 25 (16), 2092-2094, 2009 | 114 | 2009 |
Overexpression of DNA repair genes is associated with metastasis: a new hypothesis A Sarasin, A Kauffmann Mutation Research/Reviews in Mutation Research 659 (1-2), 49-55, 2008 | 114 | 2008 |
Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas S Puget, J Grill, A Valent, I Bieche, C Dantas-Barbosa, A Kauffmann, ... Journal of clinical oncology 27 (11), 1884-1892, 2009 | 105 | 2009 |