| An intact gut microbiome protects genetically predisposed mice against leukemia C Vicente-Dueñas, S Janssen, M Oldenburg, F Auer, I González-Herrero, ... Blood, The Journal of the American Society of Hematology 136 (18), 2003-2017, 2020 | 96 | 2020 |
| Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases G Rodríguez-Hernández, J Hauer, A Martín-Lorenzo, D Schäfer, ... Cancer Research 77 (16), 4365-4377, 2017 | 92 | 2017 |
| Discovery of the first-in-class dual histone deacetylase–proteasome inhibitor S Bhatia, V Krieger, M Groll, JD Osko, N Reßing, H Ahlert, A Borkhardt, ... Journal of medicinal chemistry 61 (22), 10299-10309, 2018 | 75 | 2018 |
| Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response S Bhatia, D Diedrich, B Frieg, H Ahlert, S Stein, B Bopp, F Lang, T Zang, ... Blood, The Journal of the American Society of Hematology 132 (3), 307-320, 2018 | 69 | 2018 |
| Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of dual‐targeting HDAC inhibitors and HDAC degraders (PROTACs) L Sinatra, JJ Bandolik, M Roatsch, M Sönnichsen, CT Schoeder, ... Angewandte Chemie International Edition 59 (50), 22494-22499, 2020 | 49 | 2020 |
| Multicomponent synthesis, binding mode, and structure–activity relationship of selective histone deacetylase 6 (HDAC6) inhibitors with bifurcated capping groups N Reßing, M Sönnichsen, JD Osko, A Schöler, J Schliehe-Diecks, ... Journal of medicinal chemistry 63 (18), 10339-10351, 2020 | 43 | 2020 |
| Lmo2 expression defines tumor cell identity during T‐cell leukemogenesis I García‐Ramírez, S Bhatia, G Rodríguez‐Hernández, I González‐Herrero, ... The EMBO journal 37 (14), e98783, 2018 | 40 | 2018 |
| interleukin-2-inducible t-cell Kinase Deficiency—New Patients, New insight? S Ghosh, I Drexler, S Bhatia, H Adler, AR Gennery, A Borkhardt Frontiers in Immunology 9, 979, 2018 | 40 | 2018 |
| CD16xCD33 Bispecific Killer Cell Engager (BiKE) as potential immunotherapeutic in pediatric patients with AML and biphenotypic ALL SB Reusing, DA Vallera, AR Manser, T Vatrin, S Bhatia, M Felices, ... Cancer Immunology, Immunotherapy 70 (12), 3701-3708, 2021 | 37 | 2021 |
| An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities R Flümann, T Rehkämper, P Nieper, P Pfeiffer, A Holzem, S Klein, ... Blood cancer discovery 2 (1), 70-91, 2021 | 31 | 2021 |
| Control of AC133/CD133 and impact on human hematopoietic progenitor cells through nucleolin S Bhatia, S Reister, C Mahotka, R Meisel, A Borkhardt, E Grinstein Leukemia 29 (11), 2208-2220, 2015 | 27 | 2015 |
| Solid-phase synthesis of cereblon-recruiting selective histone deacetylase 6 degraders (HDAC6 PROTACs) with antileukemic activity L Sinatra, J Yang, J Schliehe-Diecks, N Dienstbier, M Vogt, P Gebing, ... Journal of Medicinal Chemistry 65 (24), 16860-16878, 2022 | 26 | 2022 |
| 4-acyl pyrrole capped HDAC inhibitors: A new scaffold for hybrid inhibitors of BET proteins and histone deacetylases as antileukemia drug leads L Schäker-Hübner, R Warstat, H Ahlert, P Mishra, FB Kraft, ... Journal of Medicinal Chemistry 64 (19), 14620-14646, 2021 | 23 | 2021 |
| Development of a first-in-class small-molecule inhibitor of the C-terminal Hsp90 dimerization S Bhatia, L Spanier, D Bickel, N Dienstbier, V Woloschin, M Vogt, H Pols, ... ACS central science 8 (5), 636-655, 2022 | 22 | 2022 |
| The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells D Ingenhag, S Reister, F Auer, S Bhatia, S Wildenhain, D Picard, ... haematologica 104 (1), 35, 2019 | 20 | 2019 |
| Senescent Tumor CD8+ T Cells: Mechanisms of Induction and Challenges to Immunotherapy W Liu, P Stachura, HC Xu, S Bhatia, A Borkhardt, PA Lang, AA Pandyra Cancers 12 (10), 2828, 2020 | 18 | 2020 |
| Nucleolin promotes execution of the hematopoietic stem cell gene expression program C Mahotka, S Bhatia, J Kollet, E Grinstein Leukemia 32 (8), 1865-1868, 2018 | 16 | 2018 |
| Development of fluorinated peptoid-based histone deacetylase (HDAC) inhibitors for therapy-resistant acute leukemia N Reßing, J Schliehe-Diecks, PR Watson, M Sönnichsen, AD Cragin, ... Journal of medicinal chemistry 65 (22), 15457-15472, 2022 | 14 | 2022 |
| Synergistic induction of apoptosis in resistant head and neck carcinoma and leukemia by alkoxyamide-based histone deacetylase inhibitors LAA Avelar, C Schrenk, M Sönnichsen, A Hamacher, FK Hansen, ... European journal of medicinal chemistry 211, 113095, 2021 | 13 | 2021 |
| PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120 G Fazio, S Bresolin, D Silvestri, M Quadri, C Saitta, E Vendramini, ... EBioMedicine 83, 2022 | 12 | 2022 |
