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Zhongwu Lai
Zhongwu Lai
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
The sequence of the human genome
JC Venter, MD Adams, EW Myers, PW Li, RJ Mural, GG Sutton, HO Smith, ...
science 291 (5507), 1304-1351, 2001
202002001
The Genome Sequence of Drosophila melanogaster
MD Adams, SE Celniker, RA Holt, CA Evans, JD Gocayne, ...
Science 287 (5461), 2185-2195, 2000
82292000
The Genome Sequence of the Malaria Mosquito Anopheles gambiae
RA Holt, GM Subramanian, A Halpern, GG Sutton, R Charlab, ...
science 298 (5591), 129-149, 2002
25882002
A Whole-Genome Assembly of Drosophila
EW Myers, GG Sutton, AL Delcher, IM Dew, DP Fasulo, MJ Flanigan, ...
Science 287 (5461), 2196-2204, 2000
21472000
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
KS Thress, CP Paweletz, E Felip, BC Cho, D Stetson, B Dougherty, Z Lai, ...
Nature medicine 21 (6), 560-562, 2015
15462015
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research
Z Lai, A Markovets, M Ahdesmaki, B Chapman, O Hofmann, R McEwen, ...
Nucleic acids research 44 (11), e108-e108, 2016
8042016
Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster
EM Zdobnov, C Von Mering, I Letunic, D Torrents, M Suyama, RR Copley, ...
science 298 (5591), 149-159, 2002
6172002
Chromosome 2 Sequence of the Human Malaria Parasite Plasmodium falciparum
MJ Gardner, H Tettelin, DJ Carucci, LM Cummings, L Aravind, EV Koonin, ...
Science 282 (5391), 1126-1132, 1998
5751998
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome
RJ Mural, MD Adams, EW Myers, HO Smith, GLG Miklos, R Wides, ...
Science 296 (5573), 1661-1671, 2002
4852002
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
H Dev, TWW Chiang, C Lescale, I de Krijger, AG Martin, D Pilger, ...
Nature cell biology 20 (8), 954-965, 2018
3792018
Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study
SM Domchek, S Postel-Vinay, SA Im, YH Park, JP Delord, A Italiano, ...
The Lancet Oncology 21 (9), 1155-1164, 2020
3532020
Acquired resistance to the mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling in preclinical models
CA Eberlein, D Stetson, AA Markovets, KJ Al-Kadhimi, Z Lai, PR Fisher, ...
Cancer research 75 (12), 2489-2500, 2015
3182015
Human chromosome 7: DNA sequence and biology
SW Scherer, J Cheung, JR MacDonald, LR Osborne, K Nakabayashi, ...
Science 300 (5620), 767-772, 2003
2742003
Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes
DR Hodgson, BA Dougherty, Z Lai, A Fielding, L Grinsted, S Spencer, ...
British journal of cancer 119 (11), 1401-1409, 2018
2242018
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1
J Wu, K Mikule, W Wang, N Su, P Petteruti, F Gharahdaghi, E Code, X Zhu, ...
ACS chemical biology 8 (10), 2201-2208, 2013
1662013
Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol
J Wu, F Powell, NA Larsen, Z Lai, KF Byth, J Read, RF Gu, M Roth, ...
ACS chemical biology 8 (3), 643-650, 2013
1632013
The combination of the PARP inhibitor olaparib and the WEE1 inhibitor AZD1775 as a new therapeutic option for small cell lung cancer
A Lallo, KK Frese, CJ Morrow, R Sloane, S Gulati, MW Schenk, F Trapani, ...
Clinical Cancer Research 24 (20), 5153-5164, 2018
1532018
Long-term responders on olaparib maintenance in high-grade serous ovarian cancer: clinical and molecular characterization
S Lheureux, Z Lai, BA Dougherty, S Runswick, DR Hodgson, KM Timms, ...
Clinical Cancer Research 23 (15), 4086-4094, 2017
1372017
A shotgun optical map of the entire Plasmodium falciparum genome
Z Lai, J Jing, C Aston, V Clarke, J Apodaca, ET Dimalanta, DJ Carucci, ...
nature genetics 23 (3), 309-313, 1999
1321999
Defining actionable mutations for oncology therapeutic development
TH Carr, R McEwen, B Dougherty, JH Johnson, JR Dry, Z Lai, Z Ghazoui, ...
Nature Reviews Cancer 16 (5), 319-329, 2016
1162016
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