Basics of antibody phage display technology L Ledsgaard, M Kilstrup, A Karatt-Vellatt, J McCafferty, AH Laustsen Toxins 10 (6), 236, 2018 | 264 | 2018 |
Pros and cons of different therapeutic antibody formats for recombinant antivenom development AH Laustsen, JM Gutiérrez, C Knudsen, KH Johansen, ... Toxicon 146, 151-175, 2018 | 184 | 2018 |
History of envenoming therapy and current perspectives MB Pucca, FA Cerni, R Janke, E Bermúdez-Méndez, L Ledsgaard, ... Frontiers in immunology 10, 1598, 2019 | 124 | 2019 |
Advances in antibody phage display technology L Ledsgaard, A Ljungars, C Rimbault, CV Sørensen, T Tulika, J Wade, ... Drug Discovery Today 27 (8), 2151-2169, 2022 | 96 | 2022 |
Antibody cross-reactivity in antivenom research L Ledsgaard, TP Jenkins, K Davidsen, KE Krause, A Martos-Esteban, ... Toxins 10 (10), 393, 2018 | 59 | 2018 |
Engineering and design considerations for next-generation snakebite antivenoms C Knudsen, L Ledsgaard, RI Dehli, S Ahmadi, CV Sørensen, AH Laustsen Toxicon 167, 67-75, 2019 | 53 | 2019 |
An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies S Ahmadi, MB Pucca, JA Jürgensen, R Janke, L Ledsgaard, EM Schoof, ... Scientific Reports 10 (1), 10765, 2020 | 46 | 2020 |
Unity Makes Strength: Exploring Intraspecies and Interspecies Toxin Synergism between Phospholipases A2 and Cytotoxins MB Pucca, S Ahmadi, FA Cerni, L Ledsgaard, CV Sørensen, ... Frontiers in Pharmacology 11, 611, 2020 | 44 | 2020 |
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes L Ledsgaard, J Wade, TP Jenkins, K Boddum, I Oganesyan, JA Harrison, ... Nature Communications 14 (1), 682, 2023 | 37 | 2023 |
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom L Ledsgaard, AH Laustsen, U Pus, J Wade, P Villar, K Boddum, P Slavny, ... MAbs 14 (1), 2085536, 2022 | 27 | 2022 |
Generation of multivalent nanobody-based proteins with improved neutralization of long α-neurotoxins from elapid snakes J Wade, C Rimbault, H Ali, L Ledsgaard, E Rivera-de-Torre, ... Bioconjugate chemistry 33 (8), 1494-1504, 2022 | 20 | 2022 |
Cross-reactive SARS-CoV-2 neutralizing antibodies from deep mining of early patient responses G Bullen, JD Galson, G Hall, P Villar, L Moreels, L Ledsgaard, G Mattiuzzo, ... Frontiers in Immunology 12, 678570, 2021 | 20 | 2021 |
Orally active bivalent VHH construct prevents proliferation of F4+ enterotoxigenic Escherichia coli in weaned piglets BK Fiil, SW Thrane, M Pichler, T Kittilä, L Ledsgaard, S Ahmadi, ... Iscience 25 (4), 2022 | 12 | 2022 |
Discovery of a recombinant human monoclonal immunoglobulin G antibody against α-Latrotoxin from the mediterranean black widow spider (Latrodectus tredecimguttatus) S Føns, L Ledsgaard, MV Nikolaev, AA Vassilevski, CV Sørensen, ... Frontiers in Immunology 11, 587825, 2020 | 11 | 2020 |
Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy CV Sørensen, L Ledsgaard, HHK Wildenauer, CH Dahl, TW Ebersole, ... Scientific Reports 13 (1), 10181, 2023 | 10 | 2023 |
Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper CV Sørensen, J Fernández, AC Adams, HHK Wildenauer, S Schoffelen, ... Nature Communications 15 (1), 173, 2024 | 8 | 2024 |
Synthetic antibodies block receptor binding and current‐inhibiting effects of α‐cobratoxin from Naja kaouthia S Miersch, G de la Rosa, R Friis, L Ledsgaard, K Boddum, AH Laustsen, ... Protein Science 31 (5), e4296, 2022 | 8 | 2022 |
An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules RN Patel, RH Clare, L Ledsgaard, M Nys, J Kool, AH Laustsen, C Ulens, ... Biochemical pharmacology 216, 115758, 2023 | 7 | 2023 |
Basics of antibody phage display technology. Toxins 10: 236 L Ledsgaard, M Kilstrup, A Karatt-Vellatt, J McCafferty, AH Laustsen | 6 | 2018 |
Phage display assisted discovery of a pH‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library T Tulika, RW Pedersen, C Rimbault, S Ahmadi, E Rivera‐de‐Torre, ... Protein Science 32 (12), e4821, 2023 | 5 | 2023 |