EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 548 | 2012 |
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer PK Mazur, N Reynoird, P Khatri, PWTC Jansen, AW Wilkinson, S Liu, ... Nature 510 (7504), 283-287, 2014 | 409 | 2014 |
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ... Cancer discovery 3 (12), 1364-1377, 2013 | 394 | 2013 |
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ... Nature medicine 21 (10), 1163-1171, 2015 | 385 | 2015 |
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma PK Mazur, H Einwächter, M Lee, B Sipos, H Nakhai, R Rad, ... Proceedings of the National Academy of Sciences 107 (30), 13438-13443, 2010 | 262 | 2010 |
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway P Viatour, U Ehmer, LA Saddic, C Dorrell, JB Andersen, C Lin, AF Zmoos, ... Journal of experimental medicine 208 (10), 1963-1976, 2011 | 238 | 2011 |
Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice F Geisler, F Nagl, PK Mazur, M Lee, U Zimber‐Strobl, LJ Strobl, F Radtke, ... Hepatology 48 (2), 607-616, 2008 | 238 | 2008 |
IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors KL Jameson, PK Mazur, AM Zehnder, J Zhang, B Zarnegar, J Sage, ... Nature medicine 19 (5), 626-630, 2013 | 229 | 2013 |
Current Methods in the Molecular Typing of Mycobacterium tuberculosis and Other Mycobacteria T Jagielski, J Van Ingen, N Rastogi, J Dziadek, PK Mazur, J Bielecki BioMed research international 2014 (1), 645802, 2014 | 225 | 2014 |
Neat1 is a p53-inducible lincRNA essential for transformation suppression SS Mello, C Sinow, N Raj, PK Mazur, K Bieging-Rolett, DK Broz, ... Genes & development 31 (11), 1095-1108, 2017 | 201 | 2017 |
Notch signaling is required for exocrine regeneration after acute pancreatitis JT Siveke, C Lubeseder–Martellato, M Lee, PK Mazur, H Nakhai, ... Gastroenterology 134 (2), 544-555. e3, 2008 | 200 | 2008 |
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues M Aichler, C Seiler, M Tost, J Siveke, PK Mazur, P Da Silva‐Buttkus, ... The Journal of pathology 226 (5), 723-734, 2012 | 168 | 2012 |
A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma R Chen, P Khatri, PK Mazur, M Polin, Y Zheng, D Vaka, CD Hoang, ... Cancer research 74 (10), 2892-2902, 2014 | 162 | 2014 |
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer A Vallejo, N Perurena, E Guruceaga, PK Mazur, S Martinez-Canarias, ... Nature communications 8 (1), 14294, 2017 | 149 | 2017 |
Early requirement of Rac1 in a mouse model of pancreatic cancer I Heid, C Lubeseder–Martellato, B Sipos, PK Mazur, M Lesina, ... Gastroenterology 141 (2), 719-730. e7, 2011 | 145 | 2011 |
METTL13 methylation of eEF1A increases translational output to promote tumorigenesis S Liu, S Hausmann, SM Carlson, ME Fuentes, JW Francis, R Pillai, ... Cell 176 (3), 491-504. e21, 2019 | 142 | 2019 |
Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology PK Mazur, JT Siveke Gut 61 (10), 1488-1500, 2012 | 138 | 2012 |
Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors GW Krampitz, BM George, SB Willingham, JP Volkmer, K Weiskopf, ... Proceedings of the National Academy of Sciences 113 (16), 4464-4469, 2016 | 97 | 2016 |
Conditional ablation of Notch signaling in pancreatic development H Nakhai, JT Siveke, B Klein, L Mendoza-Torres, PK Mazur, H Algül, ... Oxford University Press for The Company of Biologists Limited 135 (16), 2757 …, 2008 | 97 | 2008 |
Elevated NSD3 histone methylation activity drives squamous cell lung cancer G Yuan, NM Flores, S Hausmann, SM Lofgren, V Kharchenko, ... Nature 590 (7846), 504-508, 2021 | 95 | 2021 |