Articles with public access mandates - Peter R ShepherdLearn more
Not available anywhere: 1
The academic model: Drug discovery in the academic environment
PR Shepherd, WA Denny
The Biochemist 34 (1), 4-6, 2012
Mandates: Cancer Research UK
Available somewhere: 37
The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019
KB Tran, JJ Lang, K Compton, R Xu, AR Acheson, HJ Henrikson, ...
The Lancet 400 (10352), 563-591, 2022
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health, National …
The role of phosphoinositide 3-kinase C2α in insulin signaling
M Falasca, WE Hughes, V Dominguez, G Sala, F Fostira, MQ Fang, ...
Journal of Biological Chemistry 282 (38), 28226-28236, 2007
Mandates: British Heart Foundation
G protein–coupled receptor–mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness
HA Dbouk, O Vadas, A Shymanets, JE Burke, RS Salamon, BD Khalil, ...
Science signaling 5 (253), ra89-ra89, 2012
Mandates: Swiss National Science Foundation, US National Institutes of Health, German …
Leptin rapidly improves glucose homeostasis in obese mice by increasing hypothalamic insulin sensitivity
C Koch, RA Augustine, J Steger, GK Ganjam, J Benzler, C Pracht, C Lowe, ...
Journal of Neuroscience 30 (48), 16180-16187, 2010
Mandates: US National Institutes of Health
Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition
C Wang, G Wang, X Feng, P Shepherd, J Zhang, M Tang, Z Chen, ...
Oncogene 38 (14), 2451-2463, 2019
Mandates: US National Institutes of Health
Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth
HB Pearson, J Li, VS Meniel, CM Fennell, P Waring, KG Montgomery, ...
Cancer discovery 8 (6), 764-779, 2018
Mandates: US National Institutes of Health, National Health and Medical Research …
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities
JBB Lam, KHM Chow, A Xu, KSL Lam, J Liu, NS Wong, RT Moon, ...
PloS one 4 (3), e4968, 2009
Mandates: US National Institutes of Health
Multicentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery
TM Drake, D Nepogodiev, SJ Chapman, JC Glasbey, C Khatri, CY Kong, ...
British Journal of Surgery 103 (9), 1157-1172, 2016
Mandates: US National Institutes of Health, Wellcome Trust
Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people …
M Krishnan, TJ Major, RK Topless, O Dewes, L Yu, JMD Thompson, ...
Diabetologia 61, 1603-1613, 2018
Mandates: US National Institutes of Health
The four-level project success framework: application and assessment
EM Howsawi, DM Eager, R Bagia, KD Niebecker
Organisational Project Management, 2014
Mandates: National Health and Medical Research Council, Australia
Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle
Y Liu, YC Lai, EV Hill, D Tyteca, S Carpentier, A Ingvaldsen, ...
Biochemical Journal 455 (2), 195-206, 2013
Mandates: National Fund for Scientific Research, Belgium, UK Medical Research Council
Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model
DD Britto, B Wyroba, W Chen, RA Lockwood, KB Tran, PR Shepherd, ...
Disease models & mechanisms 11 (12), dmm035998, 2018
Mandates: US National Institutes of Health
Hypothalamic glycogen synthase kinase 3β has a central role in the regulation of food intake and glucose metabolism
J Benzler, GK Ganjam, M Krüger, O Pinkenburg, M Kutschke, S Stöhr, ...
Biochemical Journal 447 (1), 175-184, 2012
Mandates: US National Institutes of Health
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta‐analysis
EuroSurg Collaborative, R Blanco‐Colino, S Lee, SK Kamarajah, P Vasko, ...
Colorectal Disease 20 (8), O215-O225, 2018
Mandates: Cancer Research UK, National Institute for Health Research, UK
Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation
J Liu, A Xu, KSL Lam, NS Wong, J Chen, PR Shepherd, Y Wang
Oncotarget 4 (10), 1804, 2013
Mandates: US National Institutes of Health, Research Grants Council, Hong Kong
A critical role for β-catenin in modulating levels of insulin secretion from β-cells by regulating actin cytoskeleton and insulin vesicle localization
B Sorrenson, E Cognard, KL Lee, WC Dissanayake, Y Fu, W Han, ...
Journal of Biological Chemistry 291 (50), 25888-25900, 2016
Mandates: US National Science Foundation
Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes
MKH Chowdhury, N Turner, NL Bentley, A Das, LE Wu, D Richani, ...
Scientific reports 7 (1), 40159, 2017
Mandates: Australian Research Council
Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and …
Z Zheng, SI Amran, J Zhu, O Schmidt-Kittler, KW Kinzler, B Vogelstein, ...
Biochemical Journal 444 (3), 529-535, 2012
Mandates: US National Institutes of Health
Extended treatment with selective phosphatidylinositol 3‐kinase and m TOR inhibitors has effects on metabolism, growth, behaviour and bone strength
GC Smith, WK Ong, JL Costa, M Watson, J Cornish, A Grey, GD Gamble, ...
The FEBS journal 280 (21), 5337-5349, 2013
Mandates: A*Star, Singapore
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