Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response I Banerjee, J Zhang, T Moore-Morris, E Pfeiffer, KS Buchholz, A Liu, ... PLoS genetics 10 (2), e1004114, 2014 | 158 | 2014 |
Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization JT Morgan, ER Pfeiffer, TL Thirkill, P Kumar, G Peng, HN Fridolfsson, ... Molecular biology of the cell 22 (22), 4324-4334, 2011 | 141 | 2011 |
Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback ER Pfeiffer, JR Tangney, JH Omens, AD McCulloch Journal of biomechanical engineering 136 (2), 021007, 2014 | 136 | 2014 |
Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model RC Lyon, V Mezzano, AT Wright, E Pfeiffer, J Chuang, K Banares, ... Human molecular genetics 23 (5), 1134-1150, 2014 | 108 | 2014 |
High Throughput Measurement of Ca++ Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment … HR Lu, R Whittaker, JH Price, R Vega, ER Pfeiffer, F Cerignoli, R Towart, ... Toxicological Sciences 148 (2), 503-516, 2015 | 95 | 2015 |
The effects of glycosaminoglycan content on the compressive modulus of cartilage engineered in type II collagen scaffolds E Pfeiffer, SM Vickers, E Frank, AJ Grodzinsky, M Spector Osteoarthritis and Cartilage 16 (10), 1237-1244, 2008 | 77 | 2008 |
Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing ER Pfeiffer, AT Wright, AG Edwards, JC Stowe, K McNall, J Tan, ... Journal of molecular and cellular cardiology 76, 265-274, 2014 | 57 | 2014 |
Desmosomal junctions are necessary for adult sinus node function V Mezzano, Y Liang, AT Wright, RC Lyon, E Pfeiffer, MY Song, Y Gu, ... Cardiovascular research 111 (3), 274-286, 2016 | 49 | 2016 |
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations G Gintant, EP Kaushik, T Feaster, S Stoelzle-Feix, Y Kanda, T Osada, ... Regulatory toxicology and pharmacology 117, 104756, 2020 | 41 | 2020 |
Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms ER Pfeiffer-Kaushik, GL Smith, B Cai, GT Dempsey, MP Hortigon-Vinagre, ... Journal of pharmacological and toxicological methods 99, 106612, 2019 | 35 | 2019 |
Specific prediction of clinical QT prolongation by kinetic image cytometry in human stem cell derived cardiomyocytes ER Pfeiffer, R Vega, PM McDonough, JH Price, R Whittaker Journal of pharmacological and toxicological methods 81, 263-273, 2016 | 35 | 2016 |
Increased cell membrane capacitance is the dominant mechanism of stretch-dependent conduction slowing in the rabbit heart: a computational study BL Oliveira, ER Pfeiffer, J Sundnes, ST Wall, AD McCulloch Cellular and molecular bioengineering 8, 237-246, 2015 | 15 | 2015 |
Cell-based two-dimensional morphological assessment system to predict cancer drug-induced cardiotoxicity using human induced pluripotent stem cell-derived cardiomyocytes T Matsui, K Miyamoto, K Yamanaka, Y Okai, EP Kaushik, K Harada, ... Toxicology and Applied Pharmacology 383, 114761, 2019 | 14 | 2019 |
Calcium regulation of an actin spring BK Tam, JH Shin, E Pfeiffer, P Matsudaira, L Mahadevan Biophysical journal 97 (4), 1125-1129, 2009 | 9 | 2009 |
Gaining Efficiency in Clinical Trials With Cardiac Biomarkers: JACC Review Topic of the Week JL Januzzi Jr, JM Canty, S Das, CR DeFilippi, GA Gintant, DE Gutstein, ... Journal of the American College of Cardiology 77 (15), 1922-1933, 2021 | 7 | 2021 |
Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes Y Okai, K Matsune, K Yamanaka, T Matsui, EP Kaushik, K Harada, ... Journal of Pharmacological and Toxicological Methods 105, 106893, 2020 | 6 | 2020 |
Kinetic image cytometry for predicting arrhythmias using human stem cell-derived cardiomyocytes ER Pfeiffer, R Whittaker, R Vega, F Cerignoli, PM McDonough, JH Price Stem Cell-Derived Models in Toxicology, 153-171, 2017 | 2 | 2017 |
Development of a pharmaceutical database as an aid to the nonclinical detection of drug-induced cardiac toxicity D De Alwis, CM Foley, E Herman, AP Hill, PK Hoffmann, Y Kanda, ... Journal of Pharmacological and Toxicological Methods 127, 107507, 2024 | 1 | 2024 |
Strain-dependent stretch-activated ion channel in Hodgkin-Huxley-form models of ventricular cardiomyocyte action potential C Villongco, E Pfeiffer BENG 260 Neurodynamics University of California San Diego, 2010 | 1 | 2010 |
15.4 The effects of glycosaminoglycan content on the compressive modulus of chondrocyte-seeded type II collagen scaffolds E Pfeiffer, SM Vickers, E Frank, A Grodzinsky, M Spector Osteoarthritis and Cartilage, B71, 2007 | 1 | 2007 |