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5'-Triphosphate RNA is the ligand for RIG-I V Hornung, J Ellegast, S Kim, K Brzózka, A Jung, H Kato, H Poeck, ... science 314 (5801), 994-997, 2006 | 3139 | 2006 |
Quantitative expression of toll-like receptor 1–10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides V Hornung, S Rothenfusser, S Britsch, A Krug, B Jahrsdörfer, T Giese, ... The Journal of immunology 168 (9), 4531-4537, 2002 | 2650 | 2002 |
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7 V Hornung, M Guenthner-Biller, C Bourquin, A Ablasser, M Schlee, ... Nature medicine 11 (3), 263-270, 2005 | 1747 | 2005 |
Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells A Krug, S Rothenfusser, V Hornung, B Jahrsdörfer, S Blackwell, ZK Ballas, ... European journal of immunology 31 (7), 2154-2163, 2001 | 1192 | 2001 |
RIG-I-dependent sensing of poly (dA: dT) through the induction of an RNA polymerase III–transcribed RNA intermediate A Ablasser, F Bauernfeind, G Hartmann, E Latz, KA Fitzgerald, V Hornung Nature immunology 10 (10), 1065-1072, 2009 | 1097 | 2009 |
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence O Gross, H Poeck, M Bscheider, C Dostert, N Hannesschläger, S Endres, ... Nature 459 (7245), 433-436, 2009 | 1088 | 2009 |
Toll‐like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL‐12 A Krug, A Towarowski, S Britsch, S Rothenfusser, V Hornung, R Bals, ... European journal of immunology 31 (10), 3026-3037, 2001 | 1071 | 2001 |
Cyclic [G (2′, 5′) pA (3′, 5′) p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase P Gao, M Ascano, Y Wu, W Barchet, BL Gaffney, T Zillinger, AA Serganov, ... Cell 153 (5), 1094-1107, 2013 | 1020 | 2013 |
Recognition of 5′ triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus M Schlee, A Roth, V Hornung, CA Hagmann, V Wimmenauer, W Barchet, ... Immunity 31 (1), 25-34, 2009 | 952 | 2009 |
CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells G Hartmann, GJ Weiner, AM Krieg Proceedings of the National Academy of Sciences 96 (16), 9305-9310, 1999 | 903 | 1999 |
Mechanism and function of a newly identified CpG DNA motif in human primary B cells G Hartmann, AM Krieg The Journal of Immunology 164 (2), 944-953, 2000 | 887 | 2000 |
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo G Hartmann, RD Weeratna, ZK Ballas, P Payette, S Blackwell, I Suparto, ... The Journal of Immunology 164 (3), 1617-1624, 2000 | 831 | 2000 |
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ... Nature immunology 11 (1), 63-69, 2010 | 667 | 2010 |
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates D Goubau, M Schlee, S Deddouche, AJ Pruijssers, T Zillinger, M Goldeck, ... Nature 514 (7522), 372-375, 2014 | 639 | 2014 |
Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases A Wollenberg, S Günther, M Moderer, S Wetzel, M Wagner, A Towarowski, ... Journal of Investigative Dermatology 119 (5), 1096-1102, 2002 | 581 | 2002 |
Structure-function analysis of STING activation by c [G (2′, 5′) pA (3′, 5′) p] and targeting by antiviral DMXAA P Gao, M Ascano, T Zillinger, W Wang, P Dai, AA Serganov, BL Gaffney, ... Cell 154 (4), 748-762, 2013 | 576 | 2013 |
High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein G Hartmann, M Tschöp, R Fischer, C Bidlingmaier, R Riepl, K Tschöp, ... Cytokine 12 (3), 246-252, 2000 | 575 | 2000 |
Discriminating self from non-self in nucleic acid sensing M Schlee, G Hartmann Nature Reviews Immunology 16 (9), 566-580, 2016 | 574 | 2016 |
Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells R Besch, H Poeck, T Hohenauer, D Senft, G Häcker, C Berking, ... The Journal of clinical investigation 119 (8), 2399-2411, 2009 | 523 | 2009 |