| DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer JM Bailey, J Alsina, ZA Rasheed, FM McAllister, YY Fu, R Plentz, H Zhang, ... Gastroenterology 146 (1), 245-256, 2014 | 340 | 2014 |
| A mouse to human search for plasma proteome changes associated with pancreatic tumor development VM Faca, KS Song, H Wang, Q Zhang, AL Krasnoselsky, LF Newcomb, ... PLoS medicine 5 (6), e123, 2008 | 318 | 2008 |
| A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer T Wirth, L Zender, B Schulte, B Mundt, R Plentz, KL Rudolph, M Manns, ... Cancer research 63 (12), 3181-3188, 2003 | 258 | 2003 |
| A critical role for notch signaling in the formation of cholangiocellular carcinomas S Zender, I Nickeleit, T Wuestefeld, I Sörensen, D Dauch, P Bozko, ... Cancer cell 23 (6), 784-795, 2013 | 240 | 2013 |
| Inhibition of γ-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma R Plentz, JS Park, AD Rhim, D Abravanel, AF Hezel, SV Sharma, ... Gastroenterology 136 (5), 1741-1749. e6, 2009 | 195 | 2009 |
| Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis RR Plentz, YN Park, A Lechel, H Kim, F Nellessen, BHE Langkopf, ... Hepatology 45 (4), 968-976, 2007 | 173 | 2007 |
| Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders J Metzger, AA Negm, RR Plentz, TJ Weismüller, J Wedemeyer, ... Gut 62 (1), 122-130, 2013 | 159 | 2013 |
| Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma RR Plentz, M Caselitz, JS Bleck, M Gebel, P Flemming, S Kubicka, ... Hepatology 40 (1), 80-86, 2004 | 150 | 2004 |
| The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo A Lechel, A Satyanarayana, Z Ju, RR Plentz, S Schaetzlein, C Rudolph, ... EMBO reports 6 (3), 275-281, 2005 | 126 | 2005 |
| Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany T Von Hahn, S Ciesek, G Wegener, RR Plentz, TJ Weismüller, ... Scandinavian journal of gastroenterology 46 (9), 1092-1098, 2011 | 125 | 2011 |
| Clinical presentation, risk factors and staging systems of cholangiocarcinoma RR Plentz, NP Malek Best practice & research Clinical gastroenterology 29 (2), 245-252, 2015 | 114 | 2015 |
| Inhibition of hedgehog signaling attenuates carcinogenesisin vitroand increases necrosis of cholangiocellular carcinoma M El Khatib, A Kalnytska, V Palagani, U Kossatz, MP Manns, NP Malek, ... Hepatology 57 (3), 1035-1045, 2013 | 102 | 2013 |
| Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer RR Plentz, SU Wiemann, P Flemming, PN Meier, S Kubicka, H Kreipe, ... Gut 52 (9), 1304-1307, 2003 | 88 | 2003 |
| Telomere shortening correlates with increasing aneuploidy of chromosome 8 in human hepatocellular carcinoma RR Plentz, B Schlegelberger, P Flemming, M Gebel, H Kreipe, MP Manns, ... Hepatology 42 (3), 522-526, 2005 | 80 | 2005 |
| Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo M El Khatib, P Bozko, V Palagani, NP Malek, L Wilkens, RR Plentz PloS one 8 (10), e77433, 2013 | 77 | 2013 |
| Combined inhibition of Notch and JAK/STAT is superior to monotherapies and impairs pancreatic cancer progression V Palagani, P Bozko, M El Khatib, H Belahmer, N Giese, B Sipos, ... Carcinogenesis 35 (4), 859-866, 2014 | 69 | 2014 |
| Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines A Müller, S Barat, X Chen, KC Bui, P Bozko, NP Malek, RR Plentz International journal of oncology 48 (5), 2025-2034, 2016 | 62 | 2016 |
| Hypoxia induced Sonic Hedgehog signaling regulates cancer stemness, epithelial-to-mesenchymal transition and invasion in cholangiocarcinoma V Bhuria, J Xing, T Scholta, KC Bui, MLT Nguyen, NP Malek, P Bozko, ... Experimental cell research 385 (2), 111671, 2019 | 60 | 2019 |
| Measurement of IgG4 in bile: a new approach for the diagnosis of IgG4-associated cholangiopathy K Vosskuhl, AA Negm, T Framke, T Weismüller, MP Manns, ... Endoscopy 44 (01), 48-52, 2012 | 58 | 2012 |
| Epithelial mesenchymal transition and pancreatic tumor initiating CD44+/EpCAM+ cells are inhibited by γ-secretase inhibitor IX V Palagani, M El Khatib, U Kossatz, P Bozko, MR Müller, MP Manns, ... Public Library of Science 7 (10), e46514, 2012 | 51 | 2012 |
