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Robert Denroche
Robert Denroche
Senior Bioinformatician, Deep Genomics
Verified email at deepgenomics.com
Title
Cited by
Cited by
Year
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
22292012
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1835*2020
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
Cancer discovery 8 (9), 1112-1129, 2018
8592018
Genomic hallmarks of localized, non-indolent prostate cancer
M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ...
Nature 541 (7637), 359-364, 2017
6132017
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ...
Nature 538 (7625), 378-382, 2016
5802016
Spatial genomic heterogeneity within localized, multifocal prostate cancer
PC Boutros, M Fraser, NJ Harding, R De Borja, D Trudel, E Lalonde, ...
Nature genetics 47 (7), 736-745, 2015
5382015
Genomics-driven precision medicine for advanced pancreatic cancer: early results from the COMPASS trial
KL Aung, SE Fischer, RE Denroche, GH Jang, A Dodd, S Creighton, ...
Clinical Cancer Research 24 (6), 1344-1354, 2018
5262018
Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution
M Chan-Seng-Yue, JC Kim, GW Wilson, K Ng, EF Figueroa, GM O’Kane, ...
Nature genetics 52 (2), 231-240, 2020
4892020
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ...
Nature communications 6 (1), 1-13, 2015
3332015
Association of distinct mutational signatures with correlates of increased immune activity in pancreatic ductal adenocarcinoma
AA Connor, RE Denroche, GH Jang, L Timms, SN Kalimuthu, I Selander, ...
JAMA oncology 3 (6), 774-783, 2017
2612017
Spatially confined sub-tumor microenvironments in pancreatic cancer
BT Grünwald, A Devisme, G Andrieux, F Vyas, K Aliar, CW McCloskey, ...
Cell 184 (22), 5577-5592. e18, 2021
2582021
GATA6 expression distinguishes classical and basal-like subtypes in advanced pancreatic cancer
GM O’Kane, BT Grünwald, GH Jang, M Masoomian, S Picardo, RC Grant, ...
Clinical Cancer Research 26 (18), 4901-4910, 2020
2492020
Integration of genomic and transcriptional features in pancreatic cancer reveals increased cell cycle progression in metastases
AA Connor, RE Denroche, GH Jang, M Lemire, A Zhang, ...
Cancer cell 35 (2), 267-282. e7, 2019
1842019
Altered gene expression along the glycolysis–cholesterol synthesis axis is associated with outcome in pancreatic cancer
JM Karasinska, JT Topham, SE Kalloger, GH Jang, RE Denroche, ...
Clinical Cancer Research 26 (1), 135-146, 2020
1522020
NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma
MR Jones, LM Williamson, JT Topham, MKC Lee, A Goytain, J Ho, ...
Clinical Cancer Research 25 (15), 4674-4681, 2019
1522019
A four-chemokine signature is associated with a T-cell–inflamed phenotype in primary and metastatic pancreatic cancer
JM Romero, B Grünwald, GH Jang, PP Bavi, A Jhaveri, M Masoomian, ...
Clinical Cancer Research 26 (8), 1997-2010, 2020
1202020
Genomic features and classification of homologous recombination deficient pancreatic ductal adenocarcinoma
T Golan, GM O’Kane, RE Denroche, M Raitses-Gurevich, RC Grant, ...
Gastroenterology 160 (6), 2119-2132. e9, 2021
1062021
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
91
Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma
RC Grant, R Denroche, GH Jang, KM Nowak, A Zhang, A Borgida, ...
Gut 70 (10), 1894-1903, 2021
682021
Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer
DMA Gendoo, RE Denroche, A Zhang, N Radulovich, GH Jang, M Lemire, ...
PLoS computational biology 15 (1), e1006596, 2019
632019
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