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Theis Thomas
Theis Thomas
Research Scientist II, Small Molecule Discovery Research, Alexion, AstraZeneca Rare Disease
Verified email at alexion.com
Title
Cited by
Cited by
Year
Lentiviral delivery of miR-133b improves functional recovery after spinal cord injury in mice
T Theis, M Yoo, CS Park, J Chen, S Kügler, KM Gibbs, M Schachner
Molecular Neurobiology 54, 4659-4671, 2017
652017
Functional role of the interaction between polysialic acid and myristoylated alanine-rich C kinase substrate at the plasma membrane
T Theis, B Mishra, M Von Der Ohe, G Loers, M Prondzynski, O Pless, ...
Journal of Biological Chemistry 288 (9), 6726-6742, 2013
512013
Functional consequences of the interactions among the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3. 3
R Kleene, C Cassens, R Bähring, T Theis, MF Xiao, A Dityatev, ...
Journal of Biological Chemistry 285 (37), 28968-28979, 2010
352010
Polysialic acid enters the cell nucleus attached to a fragment of the neural cell adhesion molecule NCAM to regulate the circadian rhythm in mouse brain
N Westphal, R Kleene, D Lutz, T Theis, M Schachner
Molecular and Cellular Neuroscience 74, 114-127, 2016
302016
Reactive oxygen species and pressure ulcer formation after traumatic injury to spinal cord and brain
S Kumar, T Theis, M Tschang, V Nagaraj, F Berthiaume
Antioxidants 10 (7), 1013, 2021
232021
Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus
N Westphal, G Loers, D Lutz, T Theis, R Kleene, M Schachner
Scientific reports 7 (1), 8622, 2017
152017
Nuclear fragments of the neural cell adhesion molecule NCAM with or without polysialic acid differentially regulate gene expression
N Westphal, T Theis, G Loers, M Schachner, R Kleene
Scientific reports 7 (1), 13631, 2017
142017
The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C
G Loers, S Astafiev, Y Hapiak, V Saini, B Mishra, S Gul, G Kaur, ...
Journal of neurochemistry 142 (3), 392-406, 2017
142017
Enhanced neuronal survival and neurite outgrowth triggered by novel small organic compounds mimicking the LewisX glycan
T Theis, AS Johal, M Kabat, S Basak, M Schachner
Molecular neurobiology 55, 8203-8215, 2018
132018
Transcriptional factors and protein biomarkers as target therapeutics in traumatic spinal cord and brain injury
S Kumar, Z Fritz, K Sulakhiya, T Theis, F Berthiaume
Current neuropharmacology 18 (11), 1092-1105, 2020
92020
Application of antibodies to neuronally expressed Nogo-A increases neuronal survival and neurite outgrowth
V Nagaraj, T Theis, AS Johal, A Seth, J Gore, N Arsha, M Patel, HB Hao, ...
International journal of molecular sciences 21 (15), 5417, 2020
92020
Myristoylated alanine‐rich C‐kinase substrate effector domain peptide improves sex‐specific recovery and axonal regrowth after spinal cord injury
T Theis, S Kumar, E Wei, J Nguyen, V Glynos, N Paranjape, ...
The FASEB Journal, 2020
92020
Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons
L Amores-Bonet, R Kleene, T Theis, M Schachner
International journal of molecular sciences 23 (17), 10027, 2022
62022
Antagonistic L1 adhesion molecule mimetic compounds inhibit glioblastoma cell migration in vitro
V Nagaraj, M Mikhail, M Baronio, A Gatto, A Nayak, T Theis, U Cavallaro, ...
Biomolecules 12 (3), 439, 2022
62022
Interplay in neural functions of cell adhesion molecule close homolog of L1 (CHL1) and Programmed Cell Death 6 (PDCD6)
G Loers, T Theis, HB Hao, R Kleene, S Arsha, N Samuel, N Arsha, ...
FASEB BioAdvances 4 (1), 43, 2022
62022
Effects of L1 adhesion molecule agonistic mimetics on signal transduction in neuronal functions
V Nagaraj, R Kim, T Martianou, S Kurian, A Nayak, M Patel, M Schachner, ...
Biochemical and Biophysical Research Communications 642, 27-34, 2023
32023
Functions of Small Organic Compounds that Mimic the HNK-1 Glycan
M Wang, T Theis, M Kabat, G Loers, LA Agre, M Schachner
International journal of molecular sciences 21 (19), 7018, 2020
32020
Adhesion molecule L1 inhibition increases infarct size in cerebral ischemia-reperfusion without change in blood-brain barrier disruption
OZ Chi, T Theis, S Kumar, A Chiricolo, X Liu, S Farooq, N Trivedi, ...
Neurological Research 43 (9), 751-759, 2021
22021
Functional roles of transient receptor potential canonical channels and myristoylated alanine-rich protein kinase C substrate as novel interaction partners of the neural cell …
T Theis
Staats-und Universitätsbibliothek Hamburg Carl von Ossietzky, 2013
22013
CHL1-deficient and wild-type male mice do not differ in locomotor recovery from spinal cord injury
T Theis, C Ayala, M Tschang, M Philip, V Nagaraj, A Shrirao, G Voronin, ...
Journal of spine research and surgery 4 (3), 96, 2022
12022
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