Articles with public access mandates - Tim DowningLearn more
Available somewhere: 23
Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Leishmania Population
MB Rogers, T Downing, BA Smith, H Imamura, M Sanders, M Svobodova, ...
PLoS genetics 10 (1), e1004092, 2014
Mandates: Wellcome Trust
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
H Imamura, T Downing, F Van den Broeck, MJ Sanders, S Rijal, S Sundar, ...
Elife 5, e12613, 2016
Mandates: Research Foundation (Flanders), Council of Scientific and Industrial …
Global genome diversity of the Leishmania donovani complex
SU Franssen, C Durrant, O Stark, B Moser, T Downing, H Imamura, ...
Elife 9, e51243, 2020
Mandates: Canadian Institutes of Health Research, Wellcome Trust, Government of Italy
In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization
CD Shaw, J Lonchamp, T Downing, H Imamura, TM Freeman, JA Cotton, ...
Molecular microbiology 99 (6), 1134-1148, 2016
Mandates: US National Science Foundation, US National Institutes of Health, UK …
Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex
T Downing, O Stark, M Vanaerschot, H Imamura, M Sanders, ...
Infection, Genetics and Evolution, 2011
Mandates: Research Foundation (Flanders)
Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones
C Ludden, AG Decano, D Jamrozy, D Pickard, D Morris, J Parkhill, ...
Microbial Genomics 6 (4), e000352, 2020
Mandates: Wellcome Trust
The genome of Leishmania adleri from a mammalian host highlights chromosome fission in Sauroleishmania
S Coughlan, P Mulhair, M Sanders, G Schonian, JA Cotton, T Downing
Scientific reports 7 (1), 43747, 2017
Mandates: Wellcome Trust
Leishmania naiffi and Leishmania guyanensis reference genomes highlight genome structure and gene evolution in the Viannia subgenus
S Coughlan, AS Taylor, E Feane, M Sanders, G Schonian, JA Cotton, ...
Royal Society open science 5 (4), 172212, 2018
Mandates: Wellcome Trust
Redeploying β-lactam antibiotics as a novel antivirulence strategy for the treatment of methicillin-resistant Staphylococcus aureus infections
EM Waters, JK Rudkin, S Coughlan, GC Clair, JN Adkins, S Gore, G Xia, ...
The Journal of infectious diseases 215 (1), 80-87, 2017
Mandates: US Department of Energy, US National Institutes of Health, Health Research …
Genetic Markers for SSG Resistance in Leishmania donovani and SSG Treatment Failure in Visceral Leishmaniasis Patients of the Indian Subcontinent
M Vanaerschot, S Decuypere, T Downing, H Imamura, O Stark, ...
The Journal of infectious diseases 206 (5), 752-755, 2012
Mandates: Research Foundation (Flanders)
Complete assembly of Escherichia coli sequence type 131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts
AG Decano, C Ludden, T Feltwell, K Judge, J Parkhill, T Downing
Msphere 4 (3), 10.1128/msphere. 00130-19, 2019
Mandates: Wellcome Trust
Tandem Amplification of the Staphylococcal Cassette Chromosome mec Element Can Drive High-Level Methicillin Resistance in Methicillin-Resistant …
LA Gallagher, S Coughlan, NS Black, P Lalor, EM Waters, B Wee, ...
Antimicrobial Agents and Chemotherapy 61 (9), 10.1128/aac. 00869-17, 2017
Mandates: Health Research Board, Ireland, UK Biotechnology and Biological Sciences …
Paternally Expressed Imprinted Genes under Positive Darwinian Selection in Arabidopsis thaliana
R Tuteja, PC McKeown, P Ryan, CC Morgan, MTA Donoghue, T Downing, ...
Molecular Biology and Evolution 36 (6), 1239-1253, 2019
Mandates: Science Foundation Ireland
Genomic and metabolomic polymorphism among experimentally selected paromomycin-resistant Leishmania donovani strains
CD Shaw, H Imamura, T Downing, G Blackburn, GD Westrop, JA Cotton, ...
Antimicrobial Agents and Chemotherapy 64 (1), 10.1128/aac. 00904-19, 2019
Mandates: US National Science Foundation, Wellcome Trust, Belgian Science Policy Office
A Polynucleotide Repeat Expansion Causing Temperature-Sensitivity Persists in Wild Irish Accessions of Arabidopsis thaliana
A Tabib, S Vishwanathan, A Seleznev, PC McKeown, T Downing, C Dent, ...
Frontiers in Plant Science 7, 1311, 2016
Mandates: Australian Research Council
High genome plasticity and frequent genetic exchange in Leishmania tropica isolates from Afghanistan, Iran and Syria
H Glans, M Lind Karlberg, R Advani, M Bradley, E Alm, B Andersson, ...
PLoS Neglected Tropical Diseases 15 (12), e0010110, 2021
Mandates: Swedish Research Council, Wellcome Trust
CaV1. 3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer
D O'reilly, T Downing, S Kouba, M Potier-Cartereau, DJ McKenna, ...
Cell Calcium 103, 102554, 2022
Mandates: Irish Research Council
Cross platform standardisation of an experimental pipeline for use in the identification of dysregulated human circulating MiRNAs
H Kelly, T Downing, NL Tuite, TJ Smith, MJ Kerin, RM Dwyer, E Clancy, ...
PLoS One 10 (9), e0137389, 2015
Mandates: Science Foundation Ireland
Aberrant calcium signalling downstream of mutations in TP53 and the PI3K/AKT pathway genes promotes disease progression and therapy resistance in triple negative breast cancer
AJ Eustace, MJ Lee, G Colley, J Roban, T Downing, PJ Buchanan
Cancer Drug Resistance 5 (3), 560, 2022
Mandates: Health Research Board, Ireland
Genome-wide variant discovery using sequence assembly, mapping and population-wide analysis
S Coughlan, S Barreira, C Seoighe, T Downing
Bioinformatics and Data Analysis in Microbiology, 51-80, 2014
Mandates: Science Foundation Ireland, Irish Research Council
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