Structural insight into substrate and inhibitor discrimination by human P-glycoprotein A Alam, J Kowal, E Broude, I Roninson, KP Locher Science 363 (6428), 753-756, 2019 | 395 | 2019 |
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? I Dulubova, X Lou, J Lu, I Huryeva, A Alam, R Schneggenburger, ... The EMBO journal 24 (16), 2839-2850, 2005 | 330 | 2005 |
Atomic structure of a Na+- and K+-conducting channel N Shi, S Ye, A Alam, L Chen, Y Jiang Nature 440 (7083), 570-574, 2006 | 296 | 2006 |
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1 K Nosol, K Romane, RN Irobalieva, A Alam, J Kowal, N Fujita, KP Locher Proceedings of the National Academy of Sciences 117 (42), 26245-26253, 2020 | 180 | 2020 |
Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1 A Alam, R Küng, J Kowal, RA McLeod, N Tremp, EV Broude, IB Roninson, ... Proceedings of the National Academy of Sciences 115 (9), E1973-E1982, 2018 | 177 | 2018 |
High-resolution structure of the open NaK channel A Alam, Y Jiang Nature structural & molecular biology 16 (1), 30-34, 2009 | 157 | 2009 |
Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites MG Derebe, DB Sauer, W Zeng, A Alam, N Shi, Y Jiang Proceedings of the National Academy of Sciences 108 (2), 598-602, 2011 | 129 | 2011 |
Structural analysis of ion selectivity in the NaK channel A Alam, Y Jiang Nature structural & molecular biology 16 (1), 35-41, 2009 | 111 | 2009 |
Structure of the human lipid exporter ABCB4 in a lipid environment JA Olsen, A Alam, J Kowal, B Stieger, KP Locher Nature structural & molecular biology 27 (1), 62-70, 2020 | 74 | 2020 |
Structural basis of transcobalamin recognition by human CD320 receptor A Alam, JS Woo, J Schmitz, B Prinz, K Root, F Chen, JS Bloch, R Zenobi, ... Nature communications 7 (1), 12100, 2016 | 51 | 2016 |
Structure and mechanism of human ABC transporters A Alam, KP Locher Annual Review of Biophysics 52 (1), 275-300, 2023 | 49 | 2023 |
Structural insight into Ca2+ specificity in tetrameric cation channels A Alam, N Shi, Y Jiang Proceedings of the National Academy of Sciences 104 (39), 15334-15339, 2007 | 48 | 2007 |
Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore MG Derebe, W Zeng, Y Li, A Alam, Y Jiang Proceedings of the National Academy of Sciences 108 (2), 592-597, 2011 | 45 | 2011 |
Structural studies of ion selectivity in tetrameric cation channels A Alam, Y Jiang Journal of General Physiology 137 (5), 397-403, 2011 | 43 | 2011 |
ABCA7 regulates brain fatty acid metabolism during LPS-induced acute inflammation T Aikawa, Y Ren, ML Holm, YW Asmann, A Alam, ML Fitzgerald, G Bu, ... Frontiers in Neuroscience 15, 647974, 2021 | 14 | 2021 |
Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment LTM Le, JR Thompson, PX Dang, J Bhandari, A Alam Communications biology 5 (1), 7, 2022 | 12 | 2022 |
Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms LTM Le, JR Thompson, S Dehghani‐Ghahnaviyeh, S Pant, PX Dang, ... The EMBO Journal 42 (3), e111065, 2023 | 9 | 2023 |
Cryo-EM structure of lipid embedded human ABCA7 at 3.6 Å resolution LTM Le, JR Thompson, T Aikawa, T Kanikeyo, A Alam BioRxiv, 2021 | 6 | 2021 |
Measuring lipid transfer protein activity using Bicelle-Dilution model membranes YG Gao, LT My Le, X Zhai, IA Boldyrev, SK Mishra, A Tischer, ... Analytical chemistry 92 (4), 3417-3425, 2020 | 6 | 2020 |
A Simple and Straightforward Approach for Generating Small, Stable, Homogeneous, Unilamellar 1-Palmitoyl 2-Oleoyl Phosphatidylcholine (POPC) Bilayer Vesicles YG Gao, A Alam, RE Brown Bio-protocol 11 (24), e4271-e4271, 2021 | 2 | 2021 |