| Adeno-associated virus vector as a platform for gene therapy delivery D Wang, PWL Tai, G Gao Nature Reviews Drug Discovery 18 (5), 358-378, 2019 | 1952 | 2019 |
| Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ... Human gene therapy 26 (7), 432-442, 2015 | 404 | 2015 |
| CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors D Wang, F Zhang, G Gao Cell 181 (1), 136-150, 2020 | 386 | 2020 |
| AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy M Kano, AE Sosulski, LH Zhang, HD Saatcioglu, D Wang, N Nagykery, ... Proceedings of the National Academy of Sciences 114 (9), E1688-E1697, 2017 | 204 | 2017 |
| AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy M Kano, AE Sosulski, LH Zhang, HD Saatcioglu, D Wang, N Nagykery, ... Proceedings of the National Academy of Sciences 114 (9), E1688-E1697, 2017 | 204 | 2017 |
| State-of-the-art human gene therapy: part Ii. gene therapy strategies and applications D Wang, G Gao Discovery medicine 18 (98), 151, 2014 | 139 | 2014 |
| The potential of adeno-associated viral vectors for gene delivery to muscle tissue D Wang, L Zhong, MA Nahid, G Gao Expert opinion on drug delivery 11 (3), 345-364, 2014 | 127 | 2014 |
| Short DNA hairpins compromise recombinant adeno-associated virus genome homogeneity J Xie, Q Mao, PWL Tai, R He, J Ai, Q Su, Y Zhu, H Ma, J Li, S Gong, ... Molecular Therapy 25 (6), 1363-1374, 2017 | 126 | 2017 |
| Suppression of premature termination codons as a therapeutic approach KM Keeling, D Wang, SE Conard, DM Bedwell Critical reviews in biochemistry and molecular biology 47 (5), 444-463, 2012 | 126 | 2012 |
| State-of-the-art human gene therapy: part I. Gene delivery technologies D Wang, G Gao Discovery medicine 18 (97), 67, 2014 | 123 | 2014 |
| Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression KM Keeling, D Wang, Y Dai, S Murugesan, B Chenna, J Clark, ... PloS one 8 (4), e60478, 2013 | 115 | 2013 |
| The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse D Wang, V Belakhov, J Kandasamy, T Baasov, SC Li, YT Li, DM Bedwell, ... Molecular genetics and metabolism 105 (1), 116-125, 2012 | 94 | 2012 |
| Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim Nature Communications 10 (1), 2958, 2019 | 86 | 2019 |
| Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses Y Yoon, D Wang, PWL Tai, J Riley, G Gao, JA Rivera-Pérez Nature Communications 9 (1), 412, 2018 | 86 | 2018 |
| In Vivo Genome Editing Partially Restores Alpha1-Antitrypsin in a Murine Model of AAT Deficiency CQ Song, D Wang, T Jiang, K O'Connor, Q Tang, L Cai, X Li, Z Weng, ... Human gene therapy 29 (8), 853-860, 2018 | 80 | 2018 |
| Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation D Wang, C Shukla, X Liu, TR Schoeb, LA Clarke, DM Bedwell, ... Molecular genetics and metabolism 99 (1), 62-71, 2010 | 78 | 2010 |
| CNS-restricted transduction and CRISPR/Cas9-mediated gene deletion with an engineered AAV vector G Murlidharan, K Sakamoto, L Rao, T Corriher, D Wang, G Gao, ... Molecular Therapy-Nucleic Acids 5, 2016 | 77 | 2016 |
| Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ... Nature communications 12 (1), 6267, 2021 | 76 | 2021 |
| AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice J Wang, Y Zhang, CA Mendonca, O Yukselen, K Muneeruddin, L Ren, ... Nature 604 (7905), 343-348, 2022 | 70 | 2022 |
| Base editing rescue of spinal muscular atrophy in cells and in mice M Arbab, Z Matuszek, KM Kray, A Du, GA Newby, AJ Blatnik, A Raguram, ... Science 380 (6642), eadg6518, 2023 | 65 | 2023 |