Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease R Pfeifle, T Rothe, N Ipseiz, HU Scherer, S Culemann, U Harre, ... Nature immunology 18 (1), 104-113, 2017 | 348 | 2017 |
Impact of immune complex size and glycosylation on IgG binding to human FcγRs A Lux, X Yu, CN Scanlan, F Nimmerjahn The Journal of Immunology 190 (8), 4315-4323, 2013 | 310 | 2013 |
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss U Harre, SC Lang, R Pfeifle, Y Rombouts, S Frühbeißer, K Amara, H Bang, ... Nature communications 6 (1), 6651, 2015 | 296 | 2015 |
FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities F Nimmerjahn, S Gordan, A Lux Trends in immunology 36 (6), 325-336, 2015 | 227 | 2015 |
FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo F Nimmerjahn, A Lux, H Albert, M Woigk, C Lehmann, D Dudziak, P Smith, ... Proceedings of the National Academy of Sciences 107 (45), 19396-19401, 2010 | 219 | 2010 |
Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice M Seeling, U Hillenhoff, JP David, G Schett, J Tuckermann, A Lux, ... Proceedings of the National Academy of Sciences 110 (26), 10729-10734, 2013 | 188 | 2013 |
Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo M Biburger, S Aschermann, I Schwab, A Lux, H Albert, H Danzer, M Woigk, ... Immunity 35 (6), 932-944, 2011 | 175 | 2011 |
The role of sialic acid as a modulator of the anti-inflammatory activity of IgG S Böhm, I Schwab, A Lux, F Nimmerjahn Seminars in immunopathology 34, 443-453, 2012 | 159 | 2012 |
Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment GF Heidkamp, J Sander, CHK Lehmann, L Heger, N Eissing, A Baranska, ... Science immunology 1 (6), eaai7677, 2016 | 143 | 2016 |
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions CH Lee, G Romain, W Yan, M Watanabe, W Charab, B Todorova, J Lee, ... Nature immunology 18 (8), 889-898, 2017 | 140 | 2017 |
The other side of immunoglobulin G: suppressor of inflammation S Aschermann, A Lux, A Baerenwaldt, M Biburger, F Nimmerjahn Clinical & Experimental Immunology 160 (2), 161-167, 2010 | 117 | 2010 |
Impact of differential glycosylation on IgG activity A Lux, F Nimmerjahn Crossroads between Innate and Adaptive Immunity III, 113-124, 2011 | 108 | 2011 |
Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo A Baerenwaldt, A Lux, H Danzer, BM Spriewald, E Ullrich, G Heidkamp, ... Proceedings of the National Academy of Sciences 108 (46), 18772-18777, 2011 | 92 | 2011 |
The Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 inhibits cellular IRF-5 E Wies, AS Hahn, K Schmidt, C Viebahn, N Rohland, A Lux, T Schellhorn, ... Journal of Biological Chemistry 284 (13), 8525-8538, 2009 | 89 | 2009 |
A monosaccharide residue is sufficient to maintain mouse and human IgG subclass activity and directs IgG effector functions to cellular Fc receptors D Kao, H Danzer, M Collin, A Groß, J Eichler, J Stambuk, G Lauc, A Lux, ... Cell reports 13 (11), 2376-2385, 2015 | 87 | 2015 |
Reply to—IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist I Schwab, A Lux, F Nimmerjahn Nature Reviews Immunology 14 (5), 349-349, 2014 | 82 | 2014 |
The pro and anti-inflammatory activities of immunoglobulin G A Lux, S Aschermann, M Biburger, F Nimmerjahn Annals of the rheumatic diseases 69 (Suppl 1), i92-i96, 2010 | 76 | 2010 |
Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection DH Yamada, H Elsaesser, A Lux, JM Timmerman, SL Morrison, ... Immunity 42 (2), 379-390, 2015 | 72 | 2015 |
Of mice and men: the need for humanized mouse models to study human IgG activity in vivo A Lux, F Nimmerjahn Journal of clinical immunology 33, 4-8, 2013 | 72 | 2013 |
Bone‐and cartilage‐protective effects of a monoclonal antibody against colony‐stimulating factor 1 receptor in experimental arthritis ML Toh, JY Bonnefoy, N Accart, S Cochin, S Pohle, H Haegel, ... Arthritis & rheumatology 66 (11), 2989-3000, 2014 | 70 | 2014 |