Articles with public access mandates - Lin JiangLearn more
Available somewhere: 49
Kemp elimination catalysts by computational enzyme design
D Röthlisberger, O Khersonsky, AM Wollacott, L Jiang, J DeChancie, ...
Nature 453 (7192), 190-195, 2008
Mandates: Swiss National Science Foundation, US National Institutes of Health, Howard …
De novo computational design of retro-aldol enzymes
L Jiang, EA Althoff, FR Clemente, L Doyle, D Rothlisberger, A Zanghellini, ...
science 319 (5868), 1387-1391, 2008
Mandates: Howard Hughes Medical Institute
Structure of the toxic core of α-synuclein from invisible crystals
JA Rodriguez, MI Ivanova, MR Sawaya, D Cascio, FE Reyes, D Shi, ...
Nature 525 (7570), 486-490, 2015
Mandates: US Department of Energy, US National Institutes of Health, Howard Hughes …
Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel
B Li, P Ge, KA Murray, P Sheth, M Zhang, G Nair, MR Sawaya, WS Shin, ...
Nature communications 9 (1), 3609, 2018
Mandates: US National Science Foundation, US National Institutes of Health, Howard …
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
SA Sievers, J Karanicolas, HW Chang, A Zhao, L Jiang, O Zirafi, ...
Nature 475 (7354), 96-100, 2011
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
A designed inhibitor of p53 aggregation rescues p53 tumor suppression in ovarian carcinomas
A Soragni, DM Janzen, LM Johnson, AG Lindgren, ATQ Nguyen, ...
Cancer cell 29 (1), 90-103, 2016
Mandates: US National Science Foundation, US Department of Energy, US National …
Towards a pharmacophore for amyloid
M Landau, MR Sawaya, KF Faull, A Laganowsky, L Jiang, SA Sievers, ...
PLoS biology 9 (6), e1001080, 2011
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates
C Liu, M Zhao, L Jiang, PN Cheng, J Park, MR Sawaya, A Pensalfini, ...
Proceedings of the National Academy of Sciences 109 (51), 20913-20918, 2012
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Robust design and optimization of retroaldol enzymes
EA Althoff, L Wang, L Jiang, L Giger, JK Lassila, Z Wang, M Smith, S Hari, ...
Protein science 21 (5), 717-726, 2012
Mandates: Swiss National Science Foundation, US National Institutes of Health, Howard …
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
X Gui, F Luo, Y Li, H Zhou, Z Qin, Z Liu, J Gu, M Xie, K Zhao, B Dai, ...
Nature communications 10 (1), 2006, 2019
Mandates: National Natural Science Foundation of China
Uncovering the mechanism of aggregation of human transthyretin
L Saelices, LM Johnson, WY Liang, MR Sawaya, D Cascio, P Ruchala, ...
Journal of Biological Chemistry 290 (48), 28932-28943, 2015
Mandates: US Department of Energy, US National Institutes of Health, Howard Hughes …
Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta
L Jiang, C Liu, D Leibly, M Landau, M Zhao, MP Hughes, DS Eisenberg
Elife 2, e00857, 2013
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs
DR Boyer, B Li, C Sun, W Fan, MR Sawaya, L Jiang, DS Eisenberg
Nature structural & molecular biology 26 (11), 1044-1052, 2019
Mandates: US National Science Foundation, US Department of Energy, US National …
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
DR Boyer, B Li, C Sun, W Fan, K Zhou, MP Hughes, MR Sawaya, L Jiang, ...
Proceedings of the National Academy of Sciences 117 (7), 3592-3602, 2020
Mandates: US National Science Foundation, US Department of Energy, US National …
NELL-1 in the treatment of osteoporotic bone loss
AW James, J Shen, X Zhang, G Asatrian, R Goyal, JH Kwak, L Jiang, ...
Nature communications 6 (1), 7362, 2015
Mandates: US Department of Energy, US National Institutes of Health
Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity
P Krotee, JA Rodriguez, MR Sawaya, D Cascio, FE Reyes, D Shi, ...
Elife 6, e19273, 2017
Mandates: US Department of Energy, US National Institutes of Health, Howard Hughes …
Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation
WS Shin, J Di, Q Cao, B Li, PM Seidler, KA Murray, G Bitan, L Jiang
Alzheimer's research & therapy 11, 1-13, 2019
Mandates: US National Institutes of Health
Precise and reversible protein-microtubule-like structure with helicity driven by dual supramolecular interactions
G Yang, X Zhang, Z Kochovski, Y Zhang, B Dai, F Sakai, L Jiang, Y Lu, ...
Journal of the American Chemical Society 138 (6), 1932-1937, 2016
Mandates: US National Institutes of Health, National Natural Science Foundation of China
Human prion protein sequence elements impede cross-species chronic wasting disease transmission
TD Kurt, L Jiang, N Fernández-Borges, C Bett, J Liu, T Yang, TR Spraker, ...
The Journal of clinical investigation 125 (4), 1485-1496, 2015
Mandates: US National Institutes of Health
Antiparallel triple-strand architecture for prefibrillar Aβ42 oligomers
L Gu, C Liu, JC Stroud, S Ngo, L Jiang, Z Guo
Journal of Biological Chemistry 289 (39), 27300-27313, 2014
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Publication and funding information is determined automatically by a computer program