Identification of Sox‐2 regulatory region which is under the control of Oct‐3/4–Sox‐2 complex M Tomioka, M Nishimoto, S Miyagi, T Katayanagi, N Fukui, H Niwa, ... Nucleic acids research 30 (14), 3202-3213, 2002 | 408 | 2002 |
Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells M Mochizuki-Kashio, Y Mishima, S Miyagi, M Negishi, A Saraya, ... Blood, The Journal of the American Society of Hematology 118 (25), 6553-6561, 2011 | 229 | 2011 |
The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma T Chiba, S Miyagi, A Saraya, R Aoki, A Seki, Y Morita, Y Yonemitsu, ... Cancer research 68 (19), 7742-7749, 2008 | 228 | 2008 |
Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders T Muto, G Sashida, M Oshima, GR Wendt, M Mochizuki-Kashio, Y Nagata, ... Journal of Experimental Medicine 210 (12), 2627-2639, 2013 | 216 | 2013 |
Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia S Tanaka, S Miyagi, G Sashida, T Chiba, J Yuan, M Mochizuki-Kashio, ... Blood, The Journal of the American Society of Hematology 120 (5), 1107-1117, 2012 | 214 | 2012 |
The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis Y Mishima, S Miyagi, A Saraya, M Negishi, M Endoh, TA Endo, T Toyoda, ... Blood, The Journal of the American Society of Hematology 118 (9), 2443-2453, 2011 | 200 | 2011 |
Oct-3/4 Maintains the Proliferative Embryonic Stem Cell State via Specific Binding to a Variant Octamer Sequence in the Regulatory Region of the UTF1 Locus M Nishimoto, S Miyagi, T Yamagishi, T Sakaguchi, H Niwa, M Muramatsu, ... Molecular and cellular biology 25 (12), 5084-5094, 2005 | 130 | 2005 |
Consequence of the loss of Sox2 in the developing brain of the mouse S Miyagi, S Masui, H Niwa, T Saito, T Shimazaki, H Okano, M Nishimoto, ... FEBS letters 582 (18), 2811-2815, 2008 | 128 | 2008 |
3‐Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor‐initiating hepatocellular carcinoma cells T Chiba, E Suzuki, M Negishi, A Saraya, S Miyagi, T Konuma, S Tanaka, ... International Journal of Cancer 130 (11), 2557-2567, 2012 | 126 | 2012 |
The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon S Miyagi, M Nishimoto, T Saito, M Ninomiya, K Sawamoto, H Okano, ... Journal of Biological Chemistry 281 (19), 13374-13381, 2006 | 119 | 2006 |
Role of SOX17 in hematopoietic development from human embryonic stem cells Y Nakajima-Takagi, M Osawa, M Oshima, H Takagi, S Miyagi, M Endoh, ... Blood, The Journal of the American Society of Hematology 121 (3), 447-458, 2013 | 114 | 2013 |
The Sox-2 Regulatory Regions Display Their Activities in Two Distinct Types of Multipotent Stem Cells S Miyagi, T Saito, K Mizutani, N Masuyama, Y Gotoh, A Iwama, ... Molecular and cellular biology 24 (10), 4207-4220, 2004 | 113 | 2004 |
shRNA screening identifies JMJD1C as being required for leukemia maintenance P Sroczynska, VA Cruickshank, JP Bukowski, S Miyagi, FO Bagger, ... Blood, The Journal of the American Society of Hematology 123 (12), 1870-1882, 2014 | 96 | 2014 |
Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf‐dependent and ‐independent manners in Mice T Chiba, A Seki, R Aoki, H Ichikawa, M Negishi, S Miyagi, H Oguro, ... Hepatology 52 (3), 1111-1123, 2010 | 94 | 2010 |
Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and-independent manners T Chiba, E Suzuki, K Yuki, Y Zen, M Oshima, S Miyagi, A Saraya, S Koide, ... PloS one 9 (1), e84807, 2014 | 93 | 2014 |
The polycomb group gene product Ezh2 regulates proliferation and differentiation of murine hepatic stem/progenitor cells R Aoki, T Chiba, S Miyagi, M Negishi, T Konuma, H Taniguchi, M Ogawa, ... Journal of hepatology 52 (6), 854-863, 2010 | 89 | 2010 |
Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells K Agger, S Miyagi, MT Pedersen, SM Kooistra, JV Johansen, K Helin Genes & development 30 (11), 1278-1288, 2016 | 81 | 2016 |
Distinct expression of polycomb group proteins EZH2 and BMI1 in hepatocellular carcinoma Y Yonemitsu, F Imazeki, T Chiba, K Fukai, Y Nagai, S Miyagi, M Arai, ... Human pathology 40 (9), 1304-1311, 2009 | 78 | 2009 |
Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes S Koide, M Oshima, K Takubo, S Yamazaki, E Nitta, A Saraya, K Aoyama, ... Blood, The Journal of the American Society of Hematology 128 (5), 638-649, 2016 | 76 | 2016 |
Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing M Negishi, A Saraya, S Miyagi, K Nagao, Y Inagaki, M Nishikawa, ... Biochemical and biophysical research communications 353 (4), 992-998, 2007 | 76 | 2007 |