Articles with public access mandates - Paula DesplatsLearn more
Not available anywhere: 1
Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington’s disease
CA Denny, PA Desplats, EA Thomas, TN Seyfried
Journal of neurochemistry 115 (3), 748-758, 2010
Mandates: US National Institutes of Health
Available somewhere: 50
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
P Desplats, HJ Lee, EJ Bae, C Patrick, E Rockenstein, L Crews, ...
Proceedings of the National Academy of Sciences 106 (31), 13010-13015, 2009
Mandates: US National Institutes of Health
In vivo demonstration that α-synuclein oligomers are toxic
B Winner, R Jappelli, SK Maji, PA Desplats, L Boyer, S Aigner, C Hetzer, ...
Proceedings of the National Academy of Sciences 108 (10), 4194-4199, 2011
Mandates: Swiss National Science Foundation, US National Institutes of Health
Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of α-synucleinopathy
L Crews, B Spencer, P Desplats, C Patrick, A Paulino, E Rockenstein, ...
PloS one 5 (2), e9313, 2010
Mandates: US National Institutes of Health
Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission
EJ Bae, HJ Lee, E Rockenstein, DH Ho, EB Park, NY Yang, P Desplats, ...
Journal of Neuroscience 32 (39), 13454-13469, 2012
Mandates: US National Institutes of Health
Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes
E Masliah, W Dumaop, D Galasko, P Desplats
Epigenetics 8 (10), 1030-1038, 2013
Mandates: US National Institutes of Health
α-Synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases
P Desplats, B Spencer, E Coffee, P Patel, S Michael, C Patrick, A Adame, ...
Journal of Biological Chemistry 286 (11), 9031-9037, 2011
Mandates: US National Institutes of Health
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
EA Thomas, G Coppola, PA Desplats, B Tang, E Soragni, R Burnett, ...
Proceedings of the National Academy of Sciences 105 (40), 15564-15569, 2008
Mandates: US National Institutes of Health
Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases
IF Tsigelny, L Crews, P Desplats, GM Shaked, Y Sharikov, H Mizuno, ...
PloS one 3 (9), e3135, 2008
Mandates: US National Institutes of Health
Cell-to-cell transmission of non-prion protein aggregates
SJ Lee, P Desplats, C Sigurdson, I Tsigelny, E Masliah
Nature Reviews Neurology 6 (12), 702-706, 2010
Mandates: US National Institutes of Health
Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation
IF Tsigelny, Y Sharikov, W Wrasidlo, T Gonzalez, PA Desplats, L Crews, ...
The FEBS journal 279 (6), 1000-1013, 2012
Mandates: US National Institutes of Health
Perfect timing: circadian rhythms, sleep, and immunity—an NIH workshop summary
JA Haspel, R Anafi, MK Brown, N Cermakian, C Depner, P Desplats, ...
JCI insight 5 (1), 2020
Mandates: US National Institutes of Health
Molecular and pathologic insights from latent HIV-1 infection in the human brain
P Desplats, W Dumaop, D Smith, A Adame, I Everall, S Letendre, R Ellis, ...
Neurology 80 (15), 1415-1423, 2013
Mandates: US National Institutes of Health
Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model
B Winner, P Desplats, C Hagl, J Klucken, R Aigner, S Ploetz, J Laemke, ...
Experimental neurology 219 (2), 543-552, 2009
Mandates: US National Institutes of Health
TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson’s disease
A Bender, P Desplats, B Spencer, E Rockenstein, A Adame, M Elstner, ...
PloS one 8 (4), e62277, 2013
Mandates: US National Institutes of Health, German Research Foundation
α-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice
L Crews, H Mizuno, P Desplats, E Rockenstein, A Adame, C Patrick, ...
Journal of Neuroscience 28 (16), 4250-4260, 2008
Mandates: US National Institutes of Health
A de novo compound targeting α-synuclein improves deficits in models of Parkinson’s disease
W Wrasidlo, IF Tsigelny, DL Price, G Dutta, E Rockenstein, TC Schwarz, ...
Brain 139 (12), 3217-3236, 2016
Mandates: US National Institutes of Health
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1
P Cronin, MJ McCarthy, ASP Lim, DP Salmon, D Galasko, E Masliah, ...
Alzheimer's & Dementia 13 (6), 689-700, 2017
Mandates: US National Institutes of Health, US Department of Veterans Affairs …
ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo
B Spencer, S Emadi, P Desplats, S Eleuteri, S Michael, K Kosberg, J Shen, ...
Molecular Therapy 22 (10), 1753-1767, 2014
Mandates: US National Institutes of Health
α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1
P Desplats, B Spencer, L Crews, P Pathel, D Morvinski-Friedmann, ...
Journal of Biological Chemistry 287 (38), 31691-31702, 2012
Mandates: US National Institutes of Health
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