Single-cell RNA-seq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma S Darmanis, SA Sloan, D Croote, M Mignardi, S Chernikova, ... Cell reports 21 (5), 1399-1410, 2017 | 842 | 2017 |
Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization JH Stafford, T Hirai, L Deng, SB Chernikova, K Urata, BL West, JM Brown Neuro-oncology 18 (6), 797-806, 2016 | 197 | 2016 |
Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability SB Chernikova, OV Razorenova, JP Higgins, BJ Sishc, M Nicolau, ... Cancer research 72 (8), 2111-2119, 2012 | 157 | 2012 |
Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks SB Chernikova, RL Wells, MM Elkind Radiation research 151 (2), 159-166, 1999 | 110 | 1999 |
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration OV Razorenova, EC Finger, R Colavitti, SB Chernikova, AD Boiko, ... Proceedings of the National Academy of Sciences 108 (5), 1931-1936, 2011 | 100 | 2011 |
Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats MJ Walters, K Ebsworth, RD Berahovich, MET Penfold, SC Liu, ... British journal of cancer 110 (5), 1179-1188, 2014 | 98 | 2014 |
Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats SC Liu, R Alomran, SB Chernikova, F Lartey, J Stafford, T Jang, ... Neuro-oncology 16 (1), 21-28, 2014 | 98 | 2014 |
Inhibiting homologous recombination for cancer therapy SB Chernikova, JC Game, JM Brown Cancer biology & therapy 13 (2), 61-68, 2012 | 88 | 2012 |
Macrophage exclusion after radiation therapy (MERT): a first in human phase I/II trial using a CXCR4 inhibitor in glioblastoma RP Thomas, S Nagpal, M Iv, SG Soltys, S Bertrand, JS Pelpola, R Ball, ... Clinical Cancer Research 25 (23), 6948-6957, 2019 | 83 | 2019 |
The role of RAD6 in recombinational repair, checkpoints and meiosis via histone modification JC Game, SB Chernikova DNA repair 8 (4), 470-482, 2009 | 82 | 2009 |
Homologous recombination is the principal pathway for the repair of DNA damage induced by tirapazamine in mammalian cells JW Evans, SB Chernikova, LA Kachnic, JP Banath, O Sordet, ... Cancer Research 68 (1), 257-265, 2008 | 79 | 2008 |
Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A Y Gu, AV Patterson, GJ Atwell, SB Chernikova, JM Brown, LH Thompson, ... Molecular cancer therapeutics 8 (6), 1714-1723, 2009 | 78 | 2009 |
Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells SB Chernikova, JA Dorth, OV Razorenova, JC Game, JM Brown Radiation research 174 (5), 558-565, 2010 | 66 | 2010 |
PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [18F]PBR06 FM Lartey, GO Ahn, B Shen, KT Cord, T Smith, JY Chua, S Rosenblum, ... Molecular Imaging and Biology 16, 109-117, 2014 | 54 | 2014 |
SDF-1 blockade enhances anti-VEGF therapy of glioblastoma and can be monitored by MRI L Deng, JH Stafford, SC Liu, SB Chernikova, M Merchant, L Recht, ... Neoplasia 19 (1), 1-7, 2017 | 53 | 2017 |
The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome KS Trego, SB Chernikova, AR Davalos, JJP Perry, LD Finger, C Ng, ... Cell Cycle 10 (12), 1998-2007, 2011 | 53 | 2011 |
Dynamin impacts homology-directed repair and breast cancer response to chemotherapy SB Chernikova, RB Nguyen, JT Truong, SS Mello, JH Stafford, MP Hay, ... The Journal of Clinical Investigation 128 (12), 5307-5321, 2018 | 18 | 2018 |
Cell cycle-dependent effects of wortmannin on radiation survival and mutation SB Chernikova, KL Lindquist, MM Elkind Radiation research 155 (6), 826-831, 2001 | 14 | 2001 |
A novel brain-permeant chemotherapeutic agent for the treatment of brain metastasis in triple-negative breast cancer J Deng, SB Chernikova, Y Wang, ML Rodriguez, SJ Andersen, ... Molecular cancer therapeutics 20 (11), 2110-2116, 2021 | 12 | 2021 |
R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells SB Chernikova, JM Brown Cell Cycle 11 (16), 2980-2984, 2012 | 9 | 2012 |