| A global reference for human genetic variation AGR 1000 Genomes Project Consortium, Auton A, Brooks LD, Durbin RM, Garrison ... Nature 526 (7571), 68-74, 2015 | 15380 | 2015 |
| An integrated map of structural variation in 2,504 human genomes PH Sudmant, T Rausch, EJ Gardner, RE Handsaker, A Abyzov, ... Nature 526 (7571), 75, 2015 | 2439 | 2015 |
| Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy J Gao, LZ Shi, H Zhao, J Chen, L Xiong, Q He, T Chen, J Roszik, ... Cell 167 (2), 397-404. e9, 2016 | 1251 | 2016 |
| Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction X Liu, Y Wang, H Lu, J Li, X Yan, M Xiao, J Hao, A Alekseev, H Khong, ... Nature, 1, 2019 | 384 | 2019 |
| Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations T Dogruluk, YH Tsang, M Espitia, F Chen, T Chen, Z Chong, V Appadurai, ... Cancer research, 2015 | 161 | 2015 |
| novoBreak: local assembly for breakpoint detection in cancer genomes Z Chong, J Ruan, M Gao, W Zhou, T Chen, X Fan, L Ding, AY Lee, ... Nature methods 14 (1), 65, 2017 | 119 | 2017 |
| Clinical actionability enhanced through deep targeted sequencing of solid tumors K Chen, F Meric-Bernstam, H Zhao, Q Zhang, N Ezzeddine, L Tang, Y Qi, ... Clinical chemistry, clinchem. 2014.231100, 2015 | 107 | 2015 |
| TransVar: a multilevel variant annotator for precision genomics W Zhou, T Chen, Z Chong, MA Rohrdanz, JM Melott, C Wakefield, J Zeng, ... Nature methods 12 (11), 1002, 2015 | 85 | 2015 |
| ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis FJDM Jian Liu, Sung-Nam Cho, Bindu Akkanti, Nili Jin, Jianqiang Mao, Weiwen ... Cell Reports, 2015 | 82 | 2015 |
| REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway L Li, Y Dang, J Zhang, W Yan, W Zhai, H Chen, K Li, L Tong, X Gao, ... Nature communications 6, 6875, 2015 | 77 | 2015 |
| Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness Y Xu, Q Chen, W Li, X Su, T Chen, Y Liu, Y Zhao, C Yu Oncogene 29 (23), 3386, 2010 | 62 | 2010 |
| ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells K Bian, NR Muppani, L Elkhadragy, W Wang, C Zhang, T Chen, S Jung, ... Oncotarget 7 (6), 6665, 2016 | 47 | 2016 |
| Bias from removing read duplication in ultra-deep sequencing experiments W Zhou, T Chen, H Zhao, AK Eterovic, F Meric-Bernstam, GB Mills, ... Bioinformatics 30 (8), 1073-1080, 2014 | 47 | 2014 |
| Mycoepoxydiene inhibits lipopolysaccharide-induced inflammatory responses through the of TRAF6 polyubiquitination Q Chen, T Chen, W Li, W Zhang, J Zhu, Y Li, Y Huang, Y Shen, C Yu PloS one 7 (9), e44890, 2012 | 40 | 2012 |
| Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types T Chen, Z Wang, W Zhou, Z Chong, F Meric-Bernstam, GB Mills, K Chen BMC genomics 17 (2), 394, 2016 | 39 | 2016 |
| Steroid receptor coactivator 3 is required for clearing bacteria and repressing inflammatory response in Escherichia coli-induced septic peritonitis Q Chen, T Chen, Y Xu, J Zhu, Y Jiang, Y Zhao, J Xu, C Yu The Journal of Immunology 185 (9), 5444-5452, 2010 | 34 | 2010 |
| Mycoepoxydiene inhibits activation of BV2 microglia stimulated by lipopolysaccharide through suppressing NF-κB, ERK 1/2 and toll-like receptor pathways X Su, Q Chen, W Chen, T Chen, W Li, Y Li, X Dou, Y Zhang, Y Shen, ... International immunopharmacology 19 (1), 88-93, 2014 | 30 | 2014 |
| SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism T Chen, Q Chen, Y Xu, Q Zhou, J Zhu, H Zhang, Q Wu, J Xu, C Yu Journal of hepatology 56 (1), 210-217, 2012 | 26 | 2012 |
| A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines M Gönen, BA Weir, GS Cowley, F Vazquez, Y Guan, A Jaiswal, ... Cell systems 5 (5), 485-497. e3, 2017 | 24 | 2017 |
| Cancer driver mutation prediction through Bayesian integration of multi-omic data Z Wang, KS Ng, T Chen, TB Kim, F Wang, K Shaw, KL Scott, ... PloS one 13 (5), e0196939, 2018 | 21 | 2018 |
Gordon MillsOregon Health & Science UniversityVerified email at ohsu.edu