| GPR109A is a G-protein–coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon M Thangaraju, GA Cresci, K Liu, S Ananth, JP Gnanaprakasam, ... Cancer research 69 (7), 2826-2832, 2009 | 766 | 2009 |
| Cysteine redox sensor in PKGIa enables oxidant-induced activation JR Burgoyne, M Madhani, F Cuello, RL Charles, JP Brennan, ... Science 317 (5843), 1393-1397, 2007 | 530 | 2007 |
| Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase S Taurin, N Sandbo, Y Qin, D Browning, NO Dulin Journal of Biological Chemistry 281 (15), 9971-9976, 2006 | 528 | 2006 |
| A role for macroautophagy in protection against 4-hydroxytamoxifen–induced cell death and the development of antiestrogen resistance JS Samaddar, VT Gaddy, J Duplantier, SP Thandavan, M Shah, MJ Smith, ... Molecular cancer therapeutics 7 (9), 2977-2987, 2008 | 235 | 2008 |
| Activation of NF-κB by bradykinin through a Gαq-and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt P Xie, DD Browning, N Hay, N Mackman, DY Richard Journal of Biological Chemistry 275 (32), 24907-24914, 2000 | 179 | 2000 |
| SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer S Elangovan, S Ramachandran, N Venkatesan, S Ananth, ... Cancer research 71 (21), 6654-6664, 2011 | 176 | 2011 |
| Bradykinin stimulates NF-kappaB activation and interleukin 1beta gene expression in cultured human fibroblasts. ZK Pan, BL Zuraw, CC Lung, ER Prossnitz, DD Browning, RD Ye The Journal of clinical investigation 98 (9), 2042-2049, 1996 | 170 | 1996 |
| Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide–cGMP–cGMP-dependent protein kinase axis regulates the … C Zaragoza, E Soria, E López, D Browning, M Balbı́n, C López-Otı́n, ... Molecular pharmacology 62 (4), 927-935, 2002 | 132 | 2002 |
| An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis S Sivaprakasam, A Gurav, AV Paschall, GL Coe, K Chaudhary, Y Cai, ... Oncogenesis 5 (6), e238-e238, 2016 | 131 | 2016 |
| Constitutive activation of NF-κB and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve Gα13 and RhoA LW Shepard, M Yang, P Xie, DD Browning, T Voyno-Yasenetskaya, ... Journal of Biological Chemistry 276 (49), 45979-45987, 2001 | 129 | 2001 |
| Nitric oxide activation of p38 mitogen-activated protein kinase in 293T fibroblasts requires cGMP-dependent protein kinase DD Browning, MP McShane, C Marty, DY Richard Journal of Biological Chemistry 275 (4), 2811-2816, 2000 | 122 | 2000 |
| Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer M Thangaraju, G Cresci, S Itagaki, J Mellinger, DD Browning, FG Berger, ... Journal of Gastrointestinal Surgery 12, 1773-1782, 2008 | 117 | 2008 |
| γ-Glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuni IHA Barnes, MC Bagnall, DD Browning, SA Thompson, G Manning, ... Microbial pathogenesis 43 (5-6), 198-207, 2007 | 113 | 2007 |
| Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells D Yang, M Thangaraju, K Greeneltch, DD Browning, PV Schoenlein, ... Cancer research 67 (7), 3301-3309, 2007 | 113 | 2007 |
| Cyclic AMP-independent activation of protein kinase A by vasoactive peptides NO Dulin, J Niu, DD Browning, DY Richard, T Voyno-Yasenetskaya Journal of Biological Chemistry 276 (24), 20827-20830, 2001 | 102 | 2001 |
| The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met is a potent chemotactic agonist for mouse formyl peptide receptor R He, L Tan, DD Browning, JM Wang, RD Ye The Journal of Immunology 165 (8), 4598-4605, 2000 | 94 | 2000 |
| Myeloid-derived suppressor cells produce IL-10 to elicit DNMT3b-dependent IRF8 silencing to promote colitis-associated colon tumorigenesis ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, ... Cell reports 25 (11), 3036-3046. e6, 2018 | 92 | 2018 |
| PKG inhibits TCF signaling in colon cancer cells by blocking β-catenin expression and activating FOXO4 IK Kwon, R Wang, M Thangaraju, H Shuang, K Liu, R Dashwood, N Dulin, ... Oncogene 29 (23), 3423-3434, 2010 | 88 | 2010 |
| Cell type-and developmental stage-specific activation of NF-κB by fMet-Leu-Phe in myeloid cells DD Browning, ZK Pan, ER Prossnitz, DY Richard Journal of Biological Chemistry 272 (12), 7995-8001, 1997 | 86 | 1997 |
| An anti-tumor role for cGMP-dependent protein kinase Y Hou, N Gupta, P Schoenlein, E Wong, R Martindale, V Ganapathy, ... Cancer letters 240 (1), 60-68, 2006 | 85 | 2006 |