Articles with public access mandates - Darren BrowningLearn more
Not available anywhere: 1
Cysteine redox sensor in PKGIa enables oxidant-induced activation
JR Burgoyne, M Madhani, F Cuello, RL Charles, JP Brennan, ...
Science 317 (5843), 1393-1397, 2007
Mandates: British Heart Foundation
Available somewhere: 26
GPR109A is a G-protein–coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
M Thangaraju, GA Cresci, K Liu, S Ananth, JP Gnanaprakasam, ...
Cancer research 69 (7), 2826-2832, 2009
Mandates: US National Institutes of Health
A role for macroautophagy in protection against 4-hydroxytamoxifen–induced cell death and the development of antiestrogen resistance
JS Samaddar, VT Gaddy, J Duplantier, SP Thandavan, M Shah, MJ Smith, ...
Molecular cancer therapeutics 7 (9), 2977-2987, 2008
Mandates: US National Institutes of Health
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer
S Elangovan, S Ramachandran, N Venkatesan, S Ananth, ...
Cancer research 71 (21), 6654-6664, 2011
Mandates: US National Institutes of Health
An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis
S Sivaprakasam, A Gurav, AV Paschall, GL Coe, K Chaudhary, Y Cai, ...
Oncogenesis 5 (6), e238-e238, 2016
Mandates: US National Institutes of Health
Myeloid-derived suppressor cells produce IL-10 to elicit DNMT3b-dependent IRF8 silencing to promote colitis-associated colon tumorigenesis
ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, ...
Cell reports 25 (11), 3036-3046. e6, 2018
Mandates: US National Institutes of Health, US Department of Veterans Affairs
PKG inhibits TCF signaling in colon cancer cells by blocking β-catenin expression and activating FOXO4
IK Kwon, R Wang, M Thangaraju, H Shuang, K Liu, R Dashwood, N Dulin, ...
Oncogene 29 (23), 3423-3434, 2010
Mandates: US National Institutes of Health
Sildenafil suppresses inflammation-driven colorectal cancer in mice
BN Islam, SK Sharman, Y Hou, AE Bridges, N Singh, S Kim, R Kolhe, ...
Cancer Prevention Research 10 (7), 377-388, 2017
Mandates: US National Institutes of Health
Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation
Y Cai, G Zhu, S Liu, Z Pan, M Quintero, CJ Poole, C Lu, H Zhu, B Islam, ...
Cell Discovery 5 (1), 7, 2019
Mandates: US National Institutes of Health, National Natural Science Foundation of China
IFN-γ Upregulates Survivin and Ifi202 Expression to Induce Survival and Proliferation of Tumor-Specific T Cells
M Zimmerman, D Yang, X Hu, F Liu, N Singh, D Browning, V Ganapathy, ...
PloS one 5 (11), e14076, 2010
Mandates: US National Institutes of Health
Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets
A Jain, A Samykutty, C Jackson, D Browning, WB Bollag, M Thangaraju, ...
Cancer letters 365 (1), 122-131, 2015
Mandates: US National Institutes of Health, US Department of Veterans Affairs …
IFNγ induces DNA methylation–silenced GPR109A expression via pSTAT1/p300 and H3K18 acetylation in colon cancer
K Bardhan, AV Paschall, D Yang, MR Chen, PS Simon, YD Bhutia, ...
Cancer immunology research 3 (7), 795-805, 2015
Mandates: US National Institutes of Health, US Department of Veterans Affairs
Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity
H Zhu, H Lemos, B Bhatt, BN Islam, A Singh, A Gurav, L Huang, ...
PLoS One 12 (9), e0183484, 2017
Mandates: US National Institutes of Health
Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium
R Wang, IK Kwon, N Singh, B Islam, K Liu, S Sridhar, F Hofmann, ...
Cell Death & Differentiation 21 (3), 427-437, 2014
Mandates: US National Institutes of Health, Swedish Council for Health, Labor and Welfare
Expression of cyclic guanosine monophosphate‐dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis
IK Kwon, PV Schoenlein, J Delk, K Liu, M Thangaraju, NO Dulin, ...
Cancer 112 (7), 1462-1470, 2008
Mandates: US National Institutes of Health
Cyclic-GMP–Elevating Agents Suppress Polyposis in ApcMin Mice by Targeting the Preneoplastic Epithelium
SK Sharman, BN Islam, Y Hou, N Singh, FG Berger, S Sridhar, W Yoo, ...
Cancer Prevention Research 11 (2), 81-92, 2018
Mandates: US National Institutes of Health
Sildenafil normalizes bowel transit in preclinical models of constipation
SK Sharman, BN Islam, Y Hou, M Usry, A Bridges, N Singh, S Sridhar, ...
PLoS One 12 (4), e0176673, 2017
Mandates: US National Institutes of Health
p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy
C Lu, JD Klement, AD Smith, D Yang, JL Waller, DD Browning, DH Munn, ...
Journal for immunotherapy of cancer 8 (2), 2020
Mandates: US National Institutes of Health, US Department of Veterans Affairs
cGMP signaling increases antioxidant gene expression by activating forkhead box O3A in the colon epithelium
R Wang, BN Islam, A Bridges, SK Sharman, M Hu, Y Hou, PR Somanath, ...
The American Journal of Pathology 187 (2), 377-389, 2017
Mandates: US National Institutes of Health
Mutation of protein kinase C phosphorylation site S1076 on α-subunits affects BKCa channel activity in HEK-293 cells
S Zhu, DD Browning, RE White, D Fulton, SA Barman
American Journal of Physiology-Lung Cellular and Molecular Physiology 297 (4 …, 2009
Mandates: US National Institutes of Health
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