Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits HL True, I Berlin, SL Lindquist Nature 431 (7005), 184-187, 2004 | 411 | 2004 |
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ... Journal of the American Chemical Society 135 (8), 2867-2870, 2013 | 359 | 2013 |
An ER-associated pathway defines endosomal architecture for controlled cargo transport MLM Jongsma, I Berlin, RHM Wijdeven, L Janssen, GMC Janssen, ... Cell 166 (1), 152-166, 2016 | 252 | 2016 |
Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway RH Wijdeven, H Janssen, L Nahidiazar, L Janssen, K Jalink, I Berlin, ... Nature communications 7 (1), 11808, 2016 | 241 | 2016 |
The EGFR odyssey–from activation to destruction in space and time J Bakker, M Spits, J Neefjes, I Berlin Journal of cell science 130 (24), 4087-4096, 2017 | 176 | 2017 |
A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes MPC Mulder, K Witting, I Berlin, JN Pruneda, KP Wu, JG Chang, R Merkx, ... Nature chemical biology 12 (7), 523-530, 2016 | 146 | 2016 |
Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8· STAM complex I Berlin, H Schwartz, PD Nash Journal of Biological Chemistry 285 (45), 34909-34921, 2010 | 116 | 2010 |
Regulation of endocytic sorting by ESCRT–DUB-mediated deubiquitination MH Wright, I Berlin, PD Nash Cell biochemistry and biophysics 60, 39-46, 2011 | 109 | 2011 |
The first step of peptide selection in antigen presentation by MHC class I molecules MA Garstka, A Fish, PHN Celie, RP Joosten, GMC Janssen, I Berlin, ... Proceedings of the National Academy of Sciences 112 (5), 1505-1510, 2015 | 103 | 2015 |
On the move: organelle dynamics during mitosis MLM Jongsma, I Berlin, J Neefjes Trends in cell biology 25 (3), 112-124, 2015 | 101 | 2015 |
Stop or go? Endosome positioning in the establishment of compartment architecture, dynamics, and function J Neefjes, MML Jongsma, I Berlin Trends in cell biology 27 (8), 580-594, 2017 | 94 | 2017 |
The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome I Berlin, KM Higginbotham, RS Dise, MI Sierra, PD Nash Journal of Biological Chemistry 285 (48), 37895-37908, 2010 | 91 | 2010 |
Ubiquitin‐based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes A de Jong, R Merkx, I Berlin, B Rodenko, RHM Wijdeven, D El Atmioui, ... ChemBioChem 13 (15), 2251-2258, 2012 | 85 | 2012 |
USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7 A Sapmaz, I Berlin, E Bos, RH Wijdeven, H Janssen, R Konietzny, ... Nature communications 10 (1), 1454, 2019 | 77 | 2019 |
SKIP‐HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport MLM Jongsma, J Bakker, B Cabukusta, N Liv, D van Elsland, J Fermie, ... The EMBO journal 39 (6), e102301, 2020 | 69 | 2020 |
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export DJH van den Boomen, A Sienkiewicz, I Berlin, MLM Jongsma, ... Nature communications 11 (1), 5559, 2020 | 67 | 2020 |
Ubiquitinylation of Igβ dictates the endocytic fate of the B cell antigen receptor M Zhang, M Veselits, S O’Neill, P Hou, AL Reddi, I Berlin, M Ikeda, ... The Journal of Immunology 179 (7), 4435-4443, 2007 | 67 | 2007 |
Human VAPome analysis reveals MOSPD1 and MOSPD3 as membrane contact site proteins interacting with FFAT-related FFNT motifs B Cabukusta, I Berlin, DM van Elsland, I Forkink, M Spits, AWM de Jong, ... Cell Reports 33 (10), 2020 | 65 | 2020 |
Stable human regulatory T cells switch to glycolysis following TNF receptor 2 costimulation S de Kivit, M Mensink, AT Hoekstra, I Berlin, RJE Derks, D Both, ... Nature metabolism 2 (10), 1046-1061, 2020 | 50 | 2020 |
Total Chemical Synthesis of SUMO and SUMO‐Based Probes for Profiling the Activity of SUMO‐Specific Proteases MPC Mulder, R Merkx, KF Witting, DS Hameed, D El Atmioui, L Lelieveld, ... Angewandte Chemie 130 (29), 9096-9100, 2018 | 50 | 2018 |