Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ... Journal of medicinal chemistry 57 (1), 42-55, 2014 | 135 | 2014 |
Targeting drug resistance in EGFR with covalent inhibitors: a structure-based design approach J Engel, A Richters, M Getlik, S Tomassi, M Keul, M Termathe, J Lategahn, ... Journal of medicinal chemistry 58 (17), 6844-6863, 2015 | 111 | 2015 |
Phenotypic identification of a novel autophagy inhibitor chemotype targeting lipid kinase VPS34 L Robke, L Laraia, MA Carnero Corrales, G Konstantinidis, M Muroi, ... Angewandte Chemie International Edition 56 (28), 8153-8157, 2017 | 63 | 2017 |
Indazole-based covalent inhibitors to target drug-resistant epidermal growth factor receptor S Tomassi, J Lategahn, J Engel, M Keul, HL Tumbrink, J Ketzer, ... Journal of medicinal chemistry 60 (6), 2361-2372, 2017 | 61 | 2017 |
Boosting Fmoc solid-phase peptide synthesis by ultrasonication F Merlino, S Tomassi, AM Yousif, A Messere, L Marinelli, P Grieco, ... Organic letters 21 (16), 6378-6382, 2019 | 52 | 2019 |
Novel Reversible Monoamine Oxidase A Inhibitors: Highly Potent and Selective 3-(1H-Pyrrol-3-yl)-2-oxazolidinones S Valente, S Tomassi, G Tempera, S Saccoccio, E Agostinelli, A Mai Journal of medicinal chemistry 54 (23), 8228-8232, 2011 | 46 | 2011 |
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells S Valente, I Lepore, C Dell'Aversana, M Tardugno, S Castellano, ... Biochimie 94 (11), 2308-2313, 2012 | 38 | 2012 |
From a Helix to a Small Cycle: Metadynamics‐Inspired αvβ6 Integrin Selective Ligands FS Di Leva, S Tomassi, S Di Maro, F Reichart, J Notni, A Dangi, ... Angewandte Chemie International Edition 57 (44), 14645-14649, 2018 | 36 | 2018 |
Exploring the N-terminal region of CXC motif chemokine 12 (CXCL12): identification of plasma-stable cyclic peptides as novel, potent CXC chemokine receptor type 4 (CXCR4 … S Di Maro, AM Trotta, D Brancaccio, FS Di Leva, V La Pietra, C Ierano, ... Journal of Medicinal Chemistry 59 (18), 8369-8380, 2016 | 34 | 2016 |
Polycomb repressive complex 2 modulation through the development of EZH2–EED interaction inhibitors and EED binders S Tomassi, A Romanelli, C Zwergel, S Valente, A Mai Journal of Medicinal Chemistry 64 (16), 11774-11797, 2021 | 32 | 2021 |
Quinoline‐based p300 histone acetyltransferase inhibitors with pro‐apoptotic activity in human leukemia U937 cells A Lenoci, S Tomassi, M Conte, R Benedetti, V Rodriguez, S Carradori, ... ChemMedChem 9 (3), 542-548, 2014 | 32 | 2014 |
Structure–activity relationships and biological characterization of a novel, potent, and serum stable CXC chemokine receptor type 4 (CXCR4) antagonist S Di Maro, FS Di Leva, AM Trotta, D Brancaccio, L Portella, M Aurilio, ... Journal of Medicinal Chemistry 60 (23), 9641-9652, 2017 | 27 | 2017 |
Ligand-based NMR study of CXC chemokine receptor type 4 (CXCR4)–ligand interactions on living cancer cells D Brancaccio, D Diana, S Di Maro, FS Di Leva, S Tomassi, R Fattorusso, ... Journal of Medicinal Chemistry 61 (7), 2910-2923, 2018 | 26 | 2018 |
Switchable protecting strategy for solid phase synthesis of DNA and RNA interacting nucleopeptides ME Mercurio, S Tomassi, M Gaglione, R Russo, A Chambery, S Lama, ... The Journal of organic chemistry 81 (23), 11612-11625, 2016 | 25 | 2016 |
Click‐Chemistry (CuAAC) Trimerization of an αvβ6 Integrin Targeting Ga‐68‐Peptide: Enhanced Contrast for in‐Vivo PET Imaging of Human Lung … NG Quigley, S Tomassi, FS Di Leva, S Di Maro, F Richter, K Steiger, ... ChemBioChem 21 (19), 2836-2843, 2020 | 24 | 2020 |
Simultaneous targeting of RGD-integrins and dual murine double minute proteins in glioblastoma multiforme F Merlino, S Daniele, V La Pietra, S Di Maro, FS Di Leva, D Brancaccio, ... Journal of Medicinal Chemistry 61 (11), 4791-4809, 2018 | 20 | 2018 |
tert‐Butylcarbamate‐Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells S Valente, D Trisciuoglio, M Tardugno, R Benedetti, D Labella, D Secci, ... ChemMedChem 8 (5), 800-811, 2013 | 18 | 2013 |
The organometallic ferrocene exhibits amplified anti-tumor activity by targeted delivery via highly selective ligands to αvβ3, αvβ6, or α5β1 integrins BS Ludwig, S Tomassi, S Di Maro, FS Di Leva, A Benge, F Reichart, ... Biomaterials 271, 120754, 2021 | 17 | 2021 |
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models M Menna, F Fiorentino, B Marrocco, A Lucidi, S Tomassi, D Cilli, ... European Journal of Medicinal Chemistry 237, 114410, 2022 | 14 | 2022 |
Novel peptide-based PET probe for non-invasive imaging of CXC chemokine receptor type 4 (CXCR4) in tumors AM Trotta, M Aurilio, C D’Alterio, C Ierano, D Di Martino, A Barbieri, ... Journal of Medicinal Chemistry 64 (6), 3449-3461, 2021 | 12 | 2021 |