Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human subjects and animal … L Egaña-Gorroño, R López-Díez, G Yepuri, LS Ramirez, S Reverdatto, ... Frontiers in cardiovascular medicine 7, 37, 2020 | 182 | 2020 |
Cellular mechanisms and consequences of glycation in atherosclerosis and obesity R López-Díez, A Shekhtman, R Ramasamy, AM Schmidt Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (12 …, 2016 | 71 | 2016 |
Complex Tissue-Specific Patterns and Distribution of Multiple RAGE Splice Variants in Different Mammals R López-Díez, A Rastrojo, O Villate, B Aguado Genome biology and evolution 5 (12), 2420-2435, 2013 | 49 | 2013 |
RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism L Senatus, R López-Díez, L Egaña-Gorroño, J Liu, J Hu, G Daffu, Q Li, ... JCI insight 5 (13), 2020 | 46 | 2020 |
Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice R López-Díez, X Shen, G Daffu, M Khursheed, J Hu, F Song, R Rosario, ... Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1536-1547, 2017 | 42 | 2017 |
Metabolism, Obesity, and Diabetes Mellitus: Recent Studies in Cellular and Animal Models and Human Subjects Highlight Mechanisms and Consequences of Metabolic Dysfunction HH Ruiz, R López Díez, L Arivazahagan, R Ramasamy, AM Schmidt Arteriosclerosis, thrombosis, and vascular biology 39 (7), e166-e174, 2019 | 27 | 2019 |
Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent … M MacLean, J Juranek, S Cuddapah, R López-Díez, HH Ruiz, J Hu, ... Journal of neuroinflammation 18 (1), 139, 2021 | 20 | 2021 |
RAGE mediates cholesterol efflux impairment in macrophages caused by human advanced glycated albumin A Machado-Lima, R López-Díez, RT Iborra, RS Pinto, G Daffu, X Shen, ... International Journal of Molecular Sciences 21 (19), 7265, 2020 | 18 | 2020 |
Glycation and a spark of ALEs (advanced lipoxidation end products)–igniting RAGE/Diaphanous-1 and cardiometabolic disease L Arivazhagan, R López-Díez, A Shekhtman, R Ramasamy, AM Schmidt Frontiers in Cardiovascular Medicine 9, 937071, 2022 | 14 | 2022 |
Inflammation Meets Metabolism Roles: for the Receptor for Advanced Glycation End Products Axis in Cardiovascular Disease L Senatus, M MacLean, L Arivazhagan, L Egaña-Gorroño, R López-Díez, ... Immunometabolism 3 (3), e210024, 2021 | 14 | 2021 |
Differential splicing, disease and drug targets O Villate, A Rastrojo, R Lopez-Diez, F Hernandez-Torres, B Aguado Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2008 | 13 | 2008 |
Neuronal–glial communication perturbations in murine SOD1G93A spinal cord M MacLean, R López-Díez, C Vasquez, PF Gugger, AM Schmidt Communications biology 5 (1), 177, 2022 | 12 | 2022 |
Diabetes and cardiovascular complications: the epidemics continue R Lopez-Diez, L Egana-Gorrono, L Senatus, A Shekhtman, R Ramasamy, ... Current Cardiology Reports 23 (7), 74, 2021 | 12 | 2021 |
DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress G Yepuri, LM Ramirez, GG Theophall, SV Reverdatto, N Quadri, ... Nature Communications 14 (1), 6900, 2023 | 10 | 2023 |
DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice L Senatus, L Egaña-Gorroño, R López-Díez, S Bergaya, JF Aranda, ... Communications biology 6 (1), 280, 2023 | 9 | 2023 |
Aldose reductase promotes diet‐induced obesity via induction of senescence in subcutaneous adipose tissue D Thiagarajan, N Quadri, S Jawahar, H Zirpoli, CH Del Pozo, ... Obesity 30 (8), 1647-1658, 2022 | 9 | 2022 |
RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism. JCI Insight. 2020; 5 (13): e137289 L Senatus, R López-Díez, L Egaña-Gorroño, J Liu, J Hu, G Daffu, Q Li, ... | 6 | |
PET imaging study of brown adipose tissue (BAT) activity in mice devoid of receptor for advanced glycation end products (RAGE) YS Ding, N Malik, S Mendoza, D Tuchman, CH Del Pozo, RL Diez, ... Journal of Biosciences 44, 1-9, 2019 | 5 | 2019 |
Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human subjects and animal … L Egaña-Gorroño, R López-Díez, G Yepuri, LS Ramirez, S Reverdatto, ... Genes and immunity 3 (3), 123-135, 2002 | 5 | 2002 |
Role of receptor for advanced glycation end products (RAGE) in regression of diabetic atherosclerosis LM Senatus, R Lopez-Diez, J Liu, H Li, G Daffu, Q Li, K Rahman, ... Arteriosclerosis, Thrombosis, and Vascular Biology 37 (suppl_1), A48-A48, 2017 | 3 | 2017 |