Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells VMA de Souza Grinevicius, MR Kviecinski, NSRS Mota, F Ourique, ... Journal of ethnopharmacology 189, 139-147, 2016 | 83 | 2016 |
Nanoparticles made from xyloglucan-block-polycaprolactone copolymers: Safety assessment for drug delivery L Mazzarino, G Loch-Neckel, L dos Santos Bubniak, F Ourique, I Otsuka, ... Toxicological Sciences 147 (1), 104-115, 2015 | 76 | 2015 |
Albendazole as a promising molecule for tumor control L Castro, MR Kviecinski, F Ourique, EB Parisotto, V Grinevicius, ... Redox biology 10, 90-99, 2016 | 73 | 2016 |
Preference ranking of colour in raw and cooked shrimps J Parisenti, LH Beirão, VLCG Tramonte, F Ourique, CC da Silveira Brito, ... International Journal of Food Science & Technology 46 (12), 2558-2561, 2011 | 72 | 2011 |
Novel pyrimidinic selenourea induces DNA damage, cell cycle arrest, and apoptosis in human breast carcinoma FAR Barbosa, T Siminski, RFS Canto, GM Almeida, NSRS Mota, ... European Journal of Medicinal Chemistry 155, 503-515, 2018 | 53 | 2018 |
DNA Damage and Inhibition of Akt Pathway in MCF‐7 Cells and Ehrlich Tumor in Mice Treated with 1, 4‐Naphthoquinones in Combination with Ascorbate F Ourique, MR Kviecinski, KB Felipe, JFG Correia, MS Farias, LS Castro, ... Oxidative medicine and cellular longevity 2015 (1), 495305, 2015 | 53 | 2015 |
Novel selenylated imidazo [1, 2-a] pyridines for breast cancer chemotherapy: Inhibition of cell proliferation by Akt-mediated regulation, DNA cleavage and apoptosis GM Almeida, J Rafique, S Saba, T Siminski, NSRS Mota, D Wilhelm Filho, ... Biochemical and biophysical research communications 503 (3), 1291-1297, 2018 | 47 | 2018 |
Inhibition of tumor proliferation associated with cell cycle arrest caused by extract and fraction from Casearia sylvestris (Salicaceae) KB Felipe, MR Kviecinski, FO da Silva, NF Bücker, MS Farias, ... Journal of ethnopharmacology 155 (3), 1492-1499, 2014 | 44 | 2014 |
Antitumor activity of conventional and supercritical extracts from Piper nigrum L. cultivar Bragantina through cell cycle arrest and apoptosis induction VMAS Grinevicius, KS Andrade, F Ourique, GA Micke, SRS Ferreira, ... The Journal of Supercritical Fluids 128, 94-101, 2017 | 36 | 2017 |
Litopenaeus vannamei muscle carotenoids versus astaxanthin: a comparison of antioxidant activity and in vitro protective effects against lipid peroxidation FO Da Silva, VLCG Tramonte, J Parisenti, JF Lima-Garcia, M Maraschin, ... Food Bioscience 9, 12-19, 2015 | 36 | 2015 |
In vivo antitumor activity of by-products of Passiflora edulis f. flavicarpa Deg. Rich in medium and long chain fatty acids evaluated through oxidative stress markers, cell … NSRS Mota, MR Kviecinski, RC Zeferino, DA de Oliveira, LC Bretanha, ... Food and Chemical Toxicology 118, 557-565, 2018 | 34 | 2018 |
In vivo inhibition of tumor progression by 5 hydroxy-1, 4-naphthoquinone (juglone) and 2-(4-hydroxyanilino)-1, 4-naphthoquinone (Q7) in combination with ascorbate F Ourique, MR Kviecinski, G Zirbel, LS Castro, AJG Castro, FRMB Silva, ... Biochemical and Biophysical Research Communications 477 (4), 640-646, 2016 | 29 | 2016 |
Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo DC Dos Santos, J Rafique, S Saba, GM Almeida, T Siminski, C Pádua, ... Journal of Biochemical and Molecular Toxicology 35 (3), e22663, 2021 | 26 | 2021 |
IP‐Se‐06, a Selenylated Imidazo[1,2‐a]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF‐1α and MAPK Signaling Inhibition, Promoting … DC Dos Santos, J Rafique, S Saba, VMAS Grinevicius, DW Filho, ... Oxidative Medicine and Cellular Longevity 2022 (1), 3710449, 2022 | 24 | 2022 |
Filho, DW; Pich, CT; Pedrosa, RC Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and … VMA De Souza Grinevicius, MR Kviecinski, NSR Santos Mota, F Ourique, ... J. Ethnopharmacol 189, 139-147, 2016 | 18 | 2016 |
Sodium orthovanadate associated with pharmacological doses of ascorbate causes an increased generation of ROS in tumor cells that inhibits proliferation and triggers apoptosis TMF Günther, MR Kviecinski, CC Baron, KB Felipe, MS Farias, ... Biochemical and Biophysical Research Communications 430 (3), 883-888, 2013 | 17 | 2013 |
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells MC Lafita-Navarro, J Liaño-Pons, A Quintanilla, I Varela, R Blanco, ... Journal of Biological Chemistry 295 (7), 2001-2017, 2020 | 15 | 2020 |
Substituted 3‑acyl‑2‑phenylamino‑1, 4‑naphthoquinones intercalate into DNA and cause genotoxicity through the increased generation of reactive oxygen species culminating in … MS Farias, CT Pich, MR Kviecinski, NCF Bucker, KB Felipe, FO Da Silva, ... Molecular Medicine Reports 10 (1), 405-410, 2014 | 15 | 2014 |
Novel dihydropyrimidinone-derived selenoesters as potential cytotoxic agents to human hepatocellular carcinoma: molecular docking and DNA fragmentation JC Benassi, FAR Barbosa, VMAS Grinevicius, F Ourique, D Coelho, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2021 | 11 | 2021 |
Pheomelanin-coated iron oxide magnetic nanoparticles: a promising candidate for negative T 2 contrast enhancement in magnetic resonance imaging ADA Zottis, JM Beltrame, LRS Lara, TG Costa, MJ Feldhaus, RC Pedrosa, ... Chemical Communications 51 (56), 11194-11197, 2015 | 11 | 2015 |