Bioisosterism: a rational approach in drug design GA Patani, EJ LaVoie Chemical reviews 96 (8), 3147-3176, 1996 | 2385 | 1996 |
Antioxidative Phenolic Compounds from Sage (Salvia officinalis) M Wang, J Li, M Rangarajan, Y Shao, EJ LaVoie, TC Huang, CT Ho Journal of Agricultural and Food Chemistry 46 (12), 4869-4873, 1998 | 918 | 1998 |
Substituted 2,5‘-Bi-1H-benzimidazoles: Topoisomerase I Inhibition and Cytotoxicity JS Kim, B Gatto, C Yu, A Liu, LF Liu, EJ LaVoie Journal of Medicinal Chemistry 39 (4), 992-998, 1996 | 370 | 1996 |
Identification of topoisomerase I as the cytotoxic target of the protoberberine alkaloid coralyne B Gatto, MM Sanders, C Yu, HY Wu, D Makhey, EJ LaVoie, LF Liu Cancer Research 56 (12), 2795-2800, 1996 | 221 | 1996 |
Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation H Wang, Y Mao, AY Chen, N Zhou, EJ LaVoie, LF Liu Biochemistry 40 (11), 3316-3323, 2001 | 209 | 2001 |
Antibacterial activity of quinoxalines, quinazolines, and 1, 5-naphthyridines AK Parhi, Y Zhang, KW Saionz, P Pradhan, M Kaul, K Trivedi, DS Pilch, ... Bioorganic & medicinal chemistry letters 23 (17), 4968-4974, 2013 | 175 | 2013 |
Structure-activity relationships of benzimidazoles and related heterocycles as topoisomerase I poisons JS Kim, Q Sun, B Gatto, C Yu, A Liu, LF Liu, EJ LaVoie Bioorganic & Medicinal Chemistry 4 (4), 621-630, 1996 | 175 | 1996 |
Antioxidative Phenolic Glycosides from Sage (Salvia officinalis) M Wang, Y Shao, J Li, N Zhu, M Rangarajan, EJ LaVoie, CT Ho Journal of Natural Products 62 (3), 454-456, 1999 | 152 | 1999 |
Synthesis and evaluation of terbenzimidazoles as topoisomerase I inhibitors Q Sun, B Gatto, C Yu, A Liu, LF Liu, EJ LaVoie Journal of Medicinal Chemistry 38 (18), 3638-3644, 1995 | 142 | 1995 |
Minor groove-directed and intercalative ligand− DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs DS Pilch, C Yu, D Makhey, EJ LaVoie, AR Srinivasan, WK Olson, ... Biochemistry 36 (41), 12542-12553, 1997 | 136 | 1997 |
Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons D Makhey, B Gatto, C Yu, A Liu, LF Liu, EJ LaVoie Bioorganic & medicinal chemistry 4 (6), 781-791, 1996 | 136 | 1996 |
Determination of the Predominant Catechins in Acacia catechu by Liquid Chromatography/Electrospray Ionization−Mass Spectrometry D Shen, Q Wu, M Wang, Y Yang, EJ Lavoie, JE Simon Journal of Agricultural and Food Chemistry 54 (9), 3219-3224, 2006 | 127 | 2006 |
5-(2-Aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Variation of N-Alkyl Substituents Modulates Sensitivity to Efflux Transporters Associated with Multidrug … AL Ruchelman, PJ Houghton, N Zhou, A Liu, LF Liu, EJ LaVoie Journal of medicinal chemistry 48 (3), 792-804, 2005 | 126 | 2005 |
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: novel topoisomerase I-Targeting anticancer agents with potent cytotoxic activity AL Ruchelman, SK Singh, A Ray, XH Wu, JM Yang, TK Li, A Liu, LF Liu, ... Bioorganic & medicinal chemistry 11 (9), 2061-2073, 2003 | 126 | 2003 |
Human Topoisomerase I Poisoning by Protoberberines: Potential Roles for Both Drug− DNA and Drug− Enzyme Interactions TK Li, E Bathory, EJ LaVoie, AR Srinivasan, WK Olson, RR Sauers, LF Liu, ... Biochemistry 39 (24), 7107-7116, 2000 | 126 | 2000 |
ANTIOXIDATIVE FLAVONOID GLYCOSIDES FROM QUINOA SEEDS (CHENOPODIUM QUINOA WILLD) N Zhu, S Sheng, D Li, EJ Lavoie, MV Karwe, RT Rosen, CHIT HO Journal of Food Lipids 8 (1), 37-44, 2001 | 124 | 2001 |
Characterization of ARC-111 as a novel topoisomerase I-targeting anticancer drug TK Li, PJ Houghton, SD Desai, P Daroui, AA Liu, ES Hars, AL Ruchelman, ... Cancer research 63 (23), 8400-8407, 2003 | 123 | 2003 |
TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus M Kaul, L Mark, Y Zhang, AK Parhi, YL Lyu, J Pawlak, S Saravolatz, ... Antimicrobial agents and chemotherapy 59 (8), 4845-4855, 2015 | 111 | 2015 |
Substituted dibenzo [c, h] cinnolines: topoisomerase I-targeting anticancer agents Y Yu, SK Singh, A Liu, TK Li, LF Liu, EJ LaVoie Bioorganic & medicinal chemistry 11 (7), 1475-1491, 2003 | 109 | 2003 |
Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles GS Minhas, DS Pilch, JE Kerrigan, EJ LaVoie, JE Rice Bioorganic & medicinal chemistry letters 16 (15), 3891-3895, 2006 | 107 | 2006 |