Poly (A) signal-dependent transcription termination occurs through a conformational change mechanism that does not require cleavage at the poly (A) site H Zhang, F Rigo, HG Martinson Molecular cell 59 (3), 437-448, 2015 | 103 | 2015 |
Activation of miR-21-regulated pathways in immune aging selects against signatures characteristic of memory T cells C Kim, B Hu, RR Jadhav, J Jin, H Zhang, MM Cavanagh, RS Akondy, ... Cell reports 25 (8), 2148-2162. e5, 2018 | 98 | 2018 |
Hallmarks of the aging T‐cell system H Zhang, CM Weyand, JJ Goronzy The FEBS journal 288 (24), 7123-7142, 2021 | 95 | 2021 |
FOXO1 deficiency impairs proteostasis in aged T cells J Jin, X Li, B Hu, C Kim, W Cao, H Zhang, CM Weyand, JJ Goronzy Science advances 6 (17), eaba1808, 2020 | 40 | 2020 |
Metabolic reprogramming in memory CD4 T cell responses of old adults RE Yanes, H Zhang, Y Shen, CM Weyand, JJ Goronzy Clinical Immunology 207, 58-67, 2019 | 36 | 2019 |
Aging-associated HELIOS deficiency in naive CD4+ T cells alters chromatin remodeling and promotes effector cell responses H Zhang, RR Jadhav, W Cao, IN Goronzy, TV Zhao, J Jin, S Ohtsuki, Z Hu, ... Nature immunology 24 (1), 96-109, 2023 | 35 | 2023 |
Activation of mTORC1 at late endosomes misdirects T cell fate decision in older individuals J Jin, C Kim, Q Xia, TM Gould, W Cao, H Zhang, X Li, D Weiskopf, ... Science immunology 6 (60), eabg0791, 2021 | 26 | 2021 |
The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age F Fang, W Cao, W Zhu, N Lam, L Li, S Gaddam, Y Wang, C Kim, ... Cell reports 37 (6), 109981, 2021 | 22 | 2021 |
CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging J Jin, Y Mu, H Zhang, I Sturmlechner, C Wang, RR Jadhav, Q Xia, ... Nature Aging, 1-17, 2023 | 12 | 2023 |
Understanding T cell aging to improve anti-viral immunity H Zhang, CM Weyand, JJ Goronzy, CE Gustafson Current Opinion in Virology 51, 127-133, 2021 | 12 | 2021 |
The GSK3β-β-catenin-TCF1 pathway improves naive T cell activation in old adults by upregulating miR-181a Z Ye, TM Gould, H Zhang, J Jin, CM Weyand, JJ Goronzy npj Aging and Mechanisms of Disease 7 (1), 1-9, 2021 | 11 | 2021 |
Lysosomes in T Cell Immunity and Aging J Jin, H Zhang, CM Weyand, JJ Goronzy Frontiers in aging, 72, 2021 | 8 | 2021 |
TRIB2 safeguards naive T cell homeostasis during aging W Cao, I Sturmlechner, H Zhang, J Jin, B Hu, RR Jadhav, F Fang, ... Cell reports 42 (3), 2023 | 7 | 2023 |
The influence of three-dimensional structure on naïve T cell homeostasis and aging S Lambert, W Cao, H Zhang, A Colville, JY Liu, CM Weyand, JJ Goronzy, ... Frontiers in Aging 3, 1045648, 2022 | 3 | 2022 |
Influence of age on functional memory T cell diversity F Fang, W Cao, W Zhu, N Lam, L Li, S Gaddam, Y Wang, C Kim, ... bioRxiv, 2021 | 2 | 2021 |
The STAT5-IRF4-BATF pathway drives heightened epigenetic remodeling in naïve CD4+ T cell responses of older adults H Zhang, RR Jadhav, W Cao, IN Goronzy, J Jin, WJ Greenleaf, ... bioRxiv, 2021 | 1 | 2021 |
PREX1 improves homeostatic proliferation to maintain a naïve CD4 T cell compartment in older age H Zhang, H Okuyama, A Jain, RR Jadhav, B Wu, I Sturmlechner, ... JCI insight, 2024 | | 2024 |
Influence of Lymph Node Microenvironment on Naive T cell Aging CE Gustafson, JY Liu, AJ Colville, W Cao, H Zhang, CM Weyand, ... The Journal of Immunology 206 (1 Supplement), 98.41-98.41, 2021 | | 2021 |
signal-dependent transcription termination occurs through a conformational change mechanism that does not require cleavage at the poly (A) site H Zhang, F Rigo, HG Martinson Mol Cell 59 (3), 437-48, 2015 | | 2015 |
Poly (A)‐dependent transcription termination does not require poly (A) site cleavage (947.1) H Zhang, H Martinson The FASEB Journal 28, 947.1, 2014 | | 2014 |