| The genetic design of signaling cascades to record receptor activation G Barnea, W Strapps, G Herrada, Y Berman, J Ong, B Kloss, R Axel, ... Proceedings of the National Academy of Sciences 105 (1), 64-69, 2008 | 742 | 2008 |
| A single administration of CRISPR/Cas9 lipid nanoparticles achieves robust and persistent in vivo genome editing JD Finn, AR Smith, MC Patel, L Shaw, MR Youniss, J van Heteren, ... Cell reports 22 (9), 2227-2235, 2018 | 709 | 2018 |
| 5′‐(E)‐Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA–GalNAc Conjugates R Parmar, JLS Willoughby, J Liu, DJ Foster, B Brigham, CS Theile, ... ChemBioChem 17 (11), 985-989, 2016 | 135 | 2016 |
| Linking Frizzled and Wnt signaling in Drosophila development A Tomlinson, WR Strapps, J Heemskerk Development 124 (22), 4515-4521, 1997 | 112 | 1997 |
| siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids [S] M Tadin-Strapps, LB Peterson, AM Cumiskey, RL Rosa, VH Mendoza, ... Journal of lipid research 52 (6), 1084-1097, 2011 | 91 | 2011 |
| Silencing myostatin using cholesterol-conjugated siRNAs induces muscle growth T Khan, H Weber, J DiMuzio, A Matter, B Dogdas, T Shah, A Thankappan, ... Molecular Therapy-Nucleic Acids 5, 2016 | 90 | 2016 |
| Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless C Chen, W Strapps, A Tomlinson, G Struhl Proceedings of the National Academy of Sciences 101 (45), 15961-15966, 2004 | 76 | 2004 |
| The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing WR Strapps, V Pickering, GT Muiru, J Rice, S Orsborn, BA Polisky, ... Nucleic Acids Research 38 (14), 4788-4797, 2010 | 65 | 2010 |
| Pharmacological characterization of a novel ENaCα siRNA (GSK2225745) with potential for the treatment of cystic fibrosis KL Clark, SA Hughes, P Bulsara, J Coates, K Moores, J Parry, M Carr, ... Molecular Therapy-Nucleic Acids 2, 2013 | 46 | 2013 |
| Transducing properties of Drosophila Frizzled proteins WR Strapps, A Tomlinson Oxford University Press for The Company of Biologists Limited 128 (23), 4829 …, 2001 | 36 | 2001 |
| Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice [S] S Han, TE Akiyama, SF Previs, K Herath, TP Roddy, KK Jensen, HP Guan, ... Journal of lipid research 54 (10), 2615-2622, 2013 | 33 | 2013 |
| Method for assaying protein—protein interaction KJ Lee, R Axel, W Strapps, G Barnea US Patent 7,049,076, 2006 | 29 | 2006 |
| Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding TQ Cai, W Wu, MK Shin, Y Xu, N Jochnowitz, Y Zhou, L Hoos, R Bentley, ... Blood Coagulation & Fibrinolysis 26 (8), 893-902, 2015 | 27 | 2015 |
| Proof-of-concept studies for siRNA-mediated gene silencing for coagulation factors in rat and rabbit Z Chen, B Luo, TQ Cai, A Thankappan, Y Xu, W Wu, J DiMuzio, T Lifsted, ... Molecular Therapy-Nucleic Acids 4, 2015 | 26 | 2015 |
| RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA) D Brown, JJ Cunningham, M Gindy, V Pickering, MG Stanton, ... US Patent 8,518,907, 2013 | 23 | 2013 |
| Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencing W Chang, Y Pei, EN Guidry, D Zewge, CA Parish, EC Sherer, J DiMuzio, ... Bioorganic & Medicinal Chemistry Letters 26 (18), 4513-4517, 2016 | 20 | 2016 |
| RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA) V Jadhav, V Pickering, W Strapps US Patent App. 13/256,146, 2012 | 19 | 2012 |
| Preclinical and translational evaluation of coagulation factor IXa as a novel therapeutic target W Ankrom, HB Wood, J Xu, W Geissler, T Bateman, MS Chatterjee, ... Pharmacology Research & Perspectives 4 (1), e00207, 2016 | 17 | 2016 |
| A single administration of CRISPR/Cas9 lipid nanoparticles achieves robust and persistent JD Finn, AR Smith, MC Patel, L Shaw, MR Youniss, J Van Heteren, ... in vivo genome editing. Cell Rep 22, 2227-2235, 2018 | 15 | 2018 |
| RNA Interference Mediated Inhibition of Connective Tissue Growth Factor (CTGF) Gene Expression Using Short Interfering Nucleic Acid (siNA) V Pickering, J Shah, W Strapps US Patent App. 13/255,695, 2012 | 12 | 2012 |