Editing DNA Methylation in the Mammalian Genome X. Shawn Liu, Hao Wu, Xiong Ji, Yonatan Stelzer, Xuebing Wu, Szymon ... Cell 167 (1), 233–247, 2016 | 1287 | 2016 |
Stromal response to Hedgehog signaling restrains pancreatic cancer progression. BPA Lee JJ1, Perera RM2, Wang H3, Wu DC4, Liu XS4, Han S5, Fitamant J2 ... Proc Natl Acad Sci U S A. 111 (30), E3091-100, 2014 | 534* | 2014 |
Rescue of fragile X syndrome neurons by DNA methylation editing of the FMR1 gene XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ... Cell 172 (5), 979-992. e6, 2018 | 471 | 2018 |
Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation W Liu, Y Wen, P Bi, X Lai, XS Liu, X Liu, S Kuang Development 139 (16), 2857-2865, 2012 | 200 | 2012 |
MeCP2 links heterochromatin condensates and neurodevelopmental disease CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ... Nature 586 (7829), 440-444, 2020 | 149 | 2020 |
Polo‐like kinase 1 phosphorylation of G2 and S‐phase‐expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery XS Liu, H Li, B Song, X Liu EMBO reports 11 (8), 626-632, 2010 | 124 | 2010 |
Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer B Song, XS Liu, SJ Rice, S Kuang, BD Elzey, SF Konieczny, TL Ratliff, ... Molecular cancer therapeutics 12 (1), 58-68, 2013 | 118 | 2013 |
Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice X Tang, J Drotar, K Li, CD Clairmont, AS Brumm, AJ Sullins, H Wu, XS Liu, ... Science translational medicine 11 (503), eaau0164, 2019 | 106 | 2019 |
Phosphorylation of CLIP‐170 by Plk1 and CK2 promotes timely formation of kinetochore–microtubule attachments H Li, XS Liu, X Yang, Y Wang, Y Wang, JR Turner, X Liu The EMBO journal 29 (17), 2953-2965, 2010 | 103 | 2010 |
Polo-like kinase 1 facilitates loss of Pten tumor suppressor-induced prostate cancer formation XS Liu, B Song, BD Elzey, TL Ratliff, SF Konieczny, L Cheng, N Ahmad, ... Journal of Biological Chemistry 286 (41), 35795-35800, 2011 | 80 | 2011 |
Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stress B Song, XS Liu, K Davis, X Liu Molecular and cellular biology 31 (23), 4844-4856, 2011 | 78 | 2011 |
Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression J Tang, X Yang, X Liu Oncogene 27 (52), 6635-6645, 2008 | 63 | 2008 |
The substrates of Plk1, beyond the functions in mitosis XS Liu, B Song, X Liu Protein & cell 1, 999-1010, 2010 | 61 | 2010 |
Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease B Song, K Davis, XS Liu, H Lee, M Smith, X Liu Aging (Albany NY) 3 (9), 846, 2011 | 59 | 2011 |
Polo-like kinase 1 (Plk1): an unexpected player in DNA replication B Song, XS Liu, X Liu Cell division 7, 1-7, 2012 | 58 | 2012 |
Polo-like kinase 1 phosphorylation of p150Glued facilitates nuclear envelope breakdown during prophase H Li, XS Liu, X Yang, B Song, Y Wang, X Liu Proceedings of the National Academy of Sciences 107 (33), 14633-14638, 2010 | 56 | 2010 |
Editing the Epigenome to Tackle Brain Disorders XS Liu, R Jaenisch Trends in Neurosciences 42 (12), 861-870, 2019 | 44 | 2019 |
Plk1 phosphorylates Sgt1 at the kinetochores to promote timely kinetochore-microtubule attachment XS Liu, B Song, J Tang, W Liu, S Kuang, X Liu Molecular and cellular biology 32 (19), 4053-4067, 2012 | 38 | 2012 |
Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons J Qian, X Guan, B Xie, C Xu, J Niu, X Tang, CH Li, HM Colecraft, ... Science Translational Medicine 15 (679), eadd4666, 2023 | 37 | 2023 |
Hippocampal cells segregate positive and negative engrams M Shpokayte, O McKissick, X Guan, B Yuan, B Rahsepar, FR Fernandez, ... Communications biology 5 (1), 1009, 2022 | 32 | 2022 |