| Diverse applications of nanomedicine B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves, AM Andrews, S Ashraf, ... ACS nano 11 (3), 2313-2381, 2017 | 1273 | 2017 |
| Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′‐O‐methyl RNA, phosphorothioates and small interfering RNA A Grünweller, E Wyszko, B Bieber, R Jahnel, VA Erdmann, J Kurreck Nucleic acids research 31 (12), 3185-3193, 2003 | 457 | 2003 |
| MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma AF Ibrahim, U Weirauch, M Thomas, A Grünweller, RK Hartmann, ... Cancer research 71 (15), 5214-5224, 2011 | 445 | 2011 |
| Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions S Schubert, A Grünweller, VA Erdmann, J Kurreck Journal of molecular biology 348 (4), 883-893, 2005 | 331 | 2005 |
| Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona-and picornaviruses C Müller, FW Schulte, K Lange-Grünweller, W Obermann, R Madhugiri, ... Antiviral research 150, 123-129, 2018 | 223 | 2018 |
| Locked nucleic acid oligonucleotides A GrÜnweiler, RK Hartmann BioDrugs 21, 235-243, 2007 | 215 | 2007 |
| Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo T Christoph, A Grünweller, J Mika, MKH Schäfer, EJ Wade, E Weihe, ... Biochemical and biophysical research communications 350 (1), 238-243, 2006 | 197 | 2006 |
| The proto-oncogene Pim-1 is a target of miR-33a M Thomas, K Lange-Grünweller, U Weirauch, D Gutsch, A Aigner, ... Oncogene 31 (7), 918-928, 2012 | 144 | 2012 |
| Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma U Weirauch, N Beckmann, M Thomas, A Grünweller, K Huber, F Bracher, ... Neoplasia 15 (7), 783-IN28, 2013 | 113 | 2013 |
| The natural compound silvestrol is a potent inhibitor of Ebola virus replication N Biedenkopf, K Lange-Grünweller, FW Schulte, A Weißer, C Müller, ... Antiviral research 137, 76-81, 2017 | 111 | 2017 |
| Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1 T Christoph, C Gillen, J Mika, A Grünweller, MKH Schäfer, K Schiene, ... Neurochemistry international 50 (1), 281-290, 2007 | 105 | 2007 |
| RNA interference as a gene-specific approach for molecular medicine A Grunweller, RK Hartmann Current medicinal chemistry 12 (26), 3143-3161, 2005 | 96 | 2005 |
| Inhibition of Zika virus replication by silvestrol F Elgner, C Sabino, M Basic, D Ploen, A Grünweller, E Hildt Viruses 10 (4), 149, 2018 | 81 | 2018 |
| RNA binding of Ebola virus VP30 is essential for activating viral transcription N Biedenkopf, J Schlereth, A Grünweller, S Becker, RK Hartmann Journal of virology 90 (16), 7481-7496, 2016 | 61 | 2016 |
| Inhibition of hepatitis E virus spread by the natural compound silvestrol M Glitscher, K Himmelsbach, K Woytinek, R Johne, A Reuter, J Spiric, ... Viruses 10 (6), 301, 2018 | 59 | 2018 |
| Silvestrol inhibits chikungunya virus replication L Henss, T Scholz, A Grünweller, BS Schnierle Viruses 10 (11), 592, 2018 | 56 | 2018 |
| Export and transport of tRNA are coupled to a multi-protein complex C Kruse, DK Willkomm, A Grünweller, T Vollbrandt, S Sommer, S Busch, ... Biochemical Journal 346 (1), 107-115, 2000 | 56 | 2000 |
| Northern blot detection of endogenous small RNAs (∼ 14 nt) in bacterial total RNA extracts BM Beckmann, A Grünweller, MHW Weber, RK Hartmann Nucleic acids research 38 (14), e147-e147, 2010 | 55 | 2010 |
| Vigilin contains a functional nuclear localisation sequence and is present in both the cytoplasm and the nucleus S Kügler, A Grünweller, C Probst, M Klinger, PK Müller, C Kruse FEBS letters 382 (3), 330-334, 1996 | 51 | 1996 |
| Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol C Müller, W Obermann, FW Schulte, K Lange-Grünweller, L Oestereich, ... Antiviral Research 175, 104706, 2020 | 50 | 2020 |
Achim AignerProfessor of Clinical Pharmacology, Leipzig University, Faculty of MedicineVerified email at medizin.uni-leipzig.de