Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine JR McDole, LW Wheeler, KG McDonald, B Wang, V Konjufca, KA Knoop, ... Nature 483 (7389), 345-349, 2012 | 1038 | 2012 |
Epithelial expression of the cytosolic retinoid chaperone cellular retinol binding protein II is essential for in vivo imprinting of local gut dendritic cells by lumenal retinoids KG McDonald, MR Leach, KWM Brooke, C Wang, LW Wheeler, EK Hanly, ... The American journal of pathology 180 (3), 984-997, 2012 | 84 | 2012 |
Preclinical evaluation of bispecific adaptor molecule controlled folate receptor CAR-T cell therapy with special focus on pediatric malignancies YJ Lu, H Chu, LW Wheeler, M Nelson, E Westrick, JF Matthaei, II Cardle, ... Frontiers in oncology 9, 151, 2019 | 53 | 2019 |
Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells LW Wheeler, NH Lents, JJ Baldassare Cell Cycle 7 (14), 2179-2188, 2008 | 52 | 2008 |
Effect of α4β7 blockade on intestinal lymphocyte subsets and lymphoid tissue development C Wang, EK Hanly, LW Wheeler, M Kaur, KG McDonald, RD Newberry Inflammatory bowel diseases 16 (10), 1751-1762, 2010 | 42 | 2010 |
Folate receptor-targeted aminopterin therapy is highly effective and specific in experimental models of autoimmune uveitis and autoimmune encephalomyelitis Y Lu, KN Wollak, VA Cross, E Westrick, LW Wheeler, TW Stinnette, ... Clinical Immunology 150 (1), 64-77, 2014 | 25 | 2014 |
CCR6 promotes steady‐state mononuclear phagocyte association with the intestinal epithelium, imprinting and immune surveillance KG McDonald, LW Wheeler, JR McDole, S Joerger, JK Gustafsson, ... Immunology 152 (4), 613-627, 2017 | 19 | 2017 |
Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents adriamycin and actinomycin D NH Lents, LW Wheeler, JJ Baldassare, BD Dynlacht Cell Cycle 7 (11), 1580-1586, 2008 | 18 | 2008 |
Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes YJ Lu, LW Wheeler, H Chu, PJ Kleindl, M Pugh, F You, S Rao, G Garcia, ... Cell Reports Medicine 2 (10), 2021 | 16 | 2021 |
The rapid activation of N-Ras by α-thrombin in fibroblasts is mediated by the specific G-protein Gαi2–Gβ1–Gγ5 and occurs in lipid rafts NH Lents, V Irintcheva, R Goel, LW Wheeler, JJ Baldassare Cellular signalling 21 (6), 1007-1014, 2009 | 10 | 2009 |
Compositions and methods for CAR T cell therapy PS Low, CHU Haiyan, YG Lee, CP Leamon, IILW Wheeler US Patent 11,759,480, 2023 | 3 | 2023 |
Adaptor controlled CAR-T cell immunotherapy for treatment of folate receptor-alpha/beta positive solid and liquid tumors YJ Lu, H Chu, LW Wheeler, M Nelson, EM Westrick, MR Vetzel, PJ Klein, ... Cancer Research 78 (13), 2018 | 2 | 2018 |
Combinatorial strategies of folate receptor-targeted chemotherapy guided by improved understanding of tumor microenvironment and immunomodulation Y Lu, LW Wheeler, VA Cross, EM Westrick, AM Lloyd, TP Johnson, ... Cancer Research 77 (13_Supplement), 4574-4574, 2017 | 2 | 2017 |
Functional folate receptor cells within synovium and fluid as therapeutic targets for osteoarthritis MF Hsueh, Y Lu, L Wheeler, SS Wellman, MP Bolognesi, VB Kraus Osteoarthritis and Cartilage 25, S42-S43, 2017 | 2 | 2017 |
Regulation of CAR-T cell therapy in real time using bispecific small molecule adaptors and monospecific competitors H Chu, Y Lu, YG Lee, L Wheeler, M Nelson, E Westrick, M Vetzel, PJ Klein, ... Cancer Research 78 (13_Supplement), 2546-2546, 2018 | 1 | 2018 |
Specificity of PSMA-617 radiotherapy for prostate cancer JA Reddy, M Nelson, LC Xu, E Westrick, M Vetzel, L Wheeler, A Felten, ... Cancer Research 78 (13_Supplement), 852-852, 2018 | 1 | 2018 |
Abstract LB-109: Adaptor controlled CAR-T cell immunotherapy for treatment of folate receptor-alpha/beta positive solid and liquid tumors YJ Lu, H Chu, LW Wheeler, M Nelson, EM Westrick, MR Vetzel, PJ Klein, ... Cancer Research 78 (13_Supplement), LB-109-LB-109, 2018 | 1 | 2018 |
Combination therapy of folate-targeted chemotherapeutics with anti-PD-1 antibody against folate receptor-positive tumors in immunocompetent murine models YJ Lu, LW Wheeler, V Cross, E Westrick, A Lloyd, CP Leamon Cancer Research 76 (14_Supplement), 262-262, 2016 | 1 | 2016 |
CCR6 expression by small intestine lamina propria dendritic cells is critical for surveillance of the luminal contents at the villous epithelial surface (CCR5P. 251) K McDonald, L Wheeler, J McDole, M Miller, R Newberry The Journal of Immunology 192 (1_Supplement), 181.5-181.5, 2014 | 1 | 2014 |
Methods for using car t cells PS Low, MC Jensen, J Matthaei, H Chu, YJ Lu, CP Leamon, LWI Wheeler | | 2020 |