Articles with public access mandates - John Dudley IsaacsLearn more
Not available anywhere: 39
Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers
PM Brown, AG Pratt, JD Isaacs
Nature Reviews Rheumatology 12 (12), 731-742, 2016
Mandates: UK Medical Research Council, National Institute for Health Research, UK
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response …
RJ Mathews, JI Robinson, M Battellino, C Wong, JC Taylor, S Eyre, ...
Annals of the rheumatic diseases 73 (6), 1202-1210, 2014
Mandates: Versus Arthritis, UK, UK Medical Research Council, National Institute for …
Development of dendritic cell-based immunotherapy for autoimmunity
CMU Hilkens, JD Isaacs, AW Thomson
International reviews of immunology 29 (2), 156-183, 2010
Mandates: US National Institutes of Health, Versus Arthritis, UK
Seronegative rheumatoid arthritis: pathogenetic and therapeutic aspects
AG Pratt, JD Isaacs
Best practice & research Clinical rheumatology 28 (4), 651-659, 2014
Mandates: UK Medical Research Council
Why remission is not enough: underlying disease mechanisms in RA that prevent cure
G Schett, Y Tanaka, JD Isaacs
Nature Reviews Rheumatology 17 (3), 135-144, 2021
Mandates: German Research Foundation, Versus Arthritis, UK, UK Medical Research …
Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients
LR Coulthard, JC Taylor, S Eyre, JI Robinson, AG Wilson, JD Isaacs, ...
Annals of the rheumatic diseases 70 (1), 98-103, 2011
Mandates: Versus Arthritis, UK
Immunogenicity of biologic agents in rheumatology
V Strand, J Goncalves, JD Isaacs
Nature Reviews Rheumatology 17 (2), 81-97, 2021
Mandates: Fundação para a Ciência e a Tecnologia, Portugal, Versus Arthritis, UK …
Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis
JI Robinson, IM Carr, DL Cooper, LH Rashid, SG Martin, P Emery, ...
Human mutation 33 (4), 741-749, 2012
Mandates: Versus Arthritis, UK
Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis
JL Bennett, AG Pratt, R Dodds, AA Sayer, JD Isaacs
Nature Reviews Rheumatology 19 (4), 239-251, 2023
Mandates: US National Institutes of Health
A negative feedback loop mediated by STAT3 limits human Th17 responses
HA Purvis, AE Anderson, DA Young, JD Isaacs, CMU Hilkens
The Journal of Immunology 193 (3), 1142-1150, 2014
Mandates: Versus Arthritis, UK, UK Medical Research Council
Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease
JI Robinson, JH Barrett, JC Taylor, M Naven, D Corscadden, A Barton, ...
Annals of the rheumatic diseases 69 (6), 1054-1057, 2010
Mandates: Versus Arthritis, UK
Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis
C Bracewell, JD Isaacs, P Emery, WF Ng
Expert opinion on biological therapy 9 (7), 909-919, 2009
Mandates: Versus Arthritis, UK
Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients
JD Bowes, C Potter, LJ Gibbons, K Hyrich, D Plant, AW Morgan, ...
Pharmacogenetics and genomics 19 (4), 319-323, 2009
Mandates: Versus Arthritis, UK
Profound invariant natural killer T-cell deficiency in inflammatory arthritis
SJ Tudhope, A von Delwig, J Falconer, A Pratt, T Woolridge, G Wilson, ...
Annals of the rheumatic diseases 69 (10), 1873-1879, 2010
Mandates: Versus Arthritis, UK
Lost in space: design of experiments and scientific exploration in a Hogarth Universe
DW Lendrem, BC Lendrem, D Woods, R Rowland-Jones, M Burke, ...
Drug Discovery Today 20 (11), 1365-1371, 2015
Mandates: UK Engineering and Physical Sciences Research Council, National Institute …
Precision medicine: the precision gap in rheumatic disease
CMA Lin, FAH Cooles, JD Isaacs
Nature Reviews Rheumatology 18 (12), 725-733, 2022
Mandates: US National Institutes of Health, UK Medical Research Council, National …
Rheumatoid arthritis: an evolutionary force in biologics
P M Brown, J D Isaacs
Current Pharmaceutical Design 21 (17), 2170-2178, 2015
Mandates: UK Medical Research Council, National Institute for Health Research, UK
Therapeutic tolerance in autoimmune disease
F Rayner, JD Isaacs
Seminars in Arthritis and Rheumatism 48 (3), 558-562, 2018
Mandates: UK Medical Research Council, National Institute for Health Research, UK
Tolerance-inducing medicines in autoimmunity: rheumatology and beyond
JA Stanway, JD Isaacs
The Lancet Rheumatology 2 (9), e565-e575, 2020
Mandates: Versus Arthritis, UK, National Institute for Health Research, UK, European …
Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response
C Potter, LJ Gibbons, JD Bowes, HJ Cordell, K Hyrich, JD Isaacs, ...
Pharmacogenetics and genomics 20 (5), 338-341, 2010
Mandates: Versus Arthritis, UK
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