Articles with public access mandates - Ian SlaymakerLearn more
Available somewhere: 12
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
B Zetsche, JS Gootenberg, OO Abudayyeh, IM Slaymaker, KS Makarova, ...
cell 163 (3), 759-771, 2015
Mandates: US Department of Energy, US National Institutes of Health
Rationally engineered Cas9 nucleases with improved specificity
IM Slaymaker, L Gao, B Zetsche, DA Scott, WX Yan, F Zhang
Science 351 (6268), 84-88, 2016
Mandates: US National Science Foundation, US National Institutes of Health, National …
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
OO Abudayyeh, JS Gootenberg, S Konermann, J Joung, IM Slaymaker, ...
Science 353 (6299), aaf5573, 2016
Mandates: US National Science Foundation, US Department of Energy, US National …
Crystal structure of Cpf1 in complex with guide RNA and target DNA
T Yamano, H Nishimasu, B Zetsche, H Hirano, IM Slaymaker, Y Li, ...
Cell 165 (4), 949-962, 2016
Mandates: US National Science Foundation, US National Institutes of Health
Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28
AA Smargon, DBT Cox, NK Pyzocha, K Zheng, IM Slaymaker, ...
Molecular cell 65 (4), 618-630. e7, 2017
Mandates: US National Science Foundation, US Department of Energy, US National …
Base editing: advances and therapeutic opportunities
EM Porto, AC Komor, IM Slaymaker, GW Yeo
Nature Reviews Drug Discovery 19 (12), 839-859, 2020
Mandates: US National Institutes of Health
Chd8 mutation leads to autistic-like behaviors and impaired striatal circuits
RJ Platt, Y Zhou, IM Slaymaker, AS Shetty, NR Weisbach, JA Kim, ...
Cell reports 19 (2), 335-350, 2017
Mandates: US National Science Foundation, US National Institutes of Health, Howard …
High-resolution structure of Cas13b and biochemical characterization of RNA targeting and cleavage
IM Slaymaker, P Mesa, MJ Kellner, S Kannan, E Brignole, J Koob, ...
Cell reports 26 (13), 3741-3751. e5, 2019
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology
IM Slaymaker, Y Fu, DB Toso, N Ranatunga, A Brewster, SL Forsburg, ...
Nucleic acids research 41 (5), 3446-3456, 2013
Mandates: US National Institutes of Health
CRISPR–Cas9 mediated DNA unwinding detected using site-directed spin labeling
NS Tangprasertchai, R Di Felice, X Zhang, IM Slaymaker, ...
ACS chemical biology 12 (6), 1489-1493, 2017
Mandates: US National Science Foundation, US National Institutes of Health
Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding
AS Brewster, IM Slaymaker, SA Afif, XS Chen
BMC Molecular Biology 11, 1-8, 2010
Mandates: US National Institutes of Health
Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase
IM Slaymaker, M Bracey, M Mileni, J Garfunkle, BF Cravatt, DL Boger, ...
Bioorganic & medicinal chemistry letters 18 (22), 5847-5850, 2008
Mandates: US National Institutes of Health
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