| Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 4790 | 2015 |
| Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer MD Ritchie, LW Hahn, N Roodi, LR Bailey, WD Dupont, FF Parl, JH Moore The American Journal of Human Genetics 69 (1), 138-147, 2001 | 2291 | 2001 |
| Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian, M Zacher, ... Nature genetics 50 (8), 1112-1121, 2018 | 2255 | 2018 |
| Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173-1186, 2014 | 2115 | 2014 |
| Estimation of the warfarin dose with clinical and pharmacogenetic data International Warfarin Pharmacogenetics Consortium New England Journal of Medicine 360 (8), 753-764, 2009 | 1856 | 2009 |
| New genetic loci link adipose and insulin biology to body fat distribution D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ... Nature 518 (7538), 187-196, 2015 | 1664 | 2015 |
| Multifactor dimensionality reduction software for detecting gene–gene and gene–environment interactions LW Hahn, MD Ritchie, JH Moore Bioinformatics 19 (3), 376-382, 2003 | 1343 | 2003 |
| PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations JC Denny, MD Ritchie, MA Basford, JM Pulley, L Bastarache, ... Bioinformatics 26 (9), 1205-1210, 2010 | 1185 | 2010 |
| Methods of integrating data to uncover genotype–phenotype interactions MD Ritchie, ER Holzinger, R Li, SA Pendergrass, D Kim Nature Reviews Genetics 16 (2), 85-97, 2015 | 1113 | 2015 |
| Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data JC Denny, L Bastarache, MD Ritchie, RJ Carroll, R Zink, JD Mosley, ... Nature biotechnology 31 (12), 1102-1111, 2013 | 1023 | 2013 |
| Genetic and pharmacologic inactivation of ANGPTL3 and cardiovascular disease FE Dewey, V Gusarova, RL Dunbar, C O’Dushlaine, C Schurmann, ... New England Journal of Medicine 377 (3), 211-221, 2017 | 800 | 2017 |
| The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies CA McCarty, RL Chisholm, CG Chute, IJ Kullo, GP Jarvik, EB Larson, R Li, ... BMC medical genomics 4, 1-11, 2011 | 775 | 2011 |
| Genetic determinants of response to warfarin during initial anticoagulation UI Schwarz, MD Ritchie, Y Bradford, C Li, SM Dudek, A Frye-Anderson, ... New England Journal of Medicine 358 (10), 999-1008, 2008 | 772 | 2008 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 771 | 2021 |
| Meta-analysis identifies six new susceptibility loci for atrial fibrillation PT Ellinor, KL Lunetta, CM Albert, NL Glazer, MD Ritchie, AV Smith, ... Nature genetics 44 (6), 670-675, 2012 | 687 | 2012 |
| Power of multifactor dimensionality reduction for detecting gene‐gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity MD Ritchie, LW Hahn, JH Moore Genetic Epidemiology: The Official Publication of the International Genetic …, 2003 | 663 | 2003 |
| The electronic medical records and genomics (eMERGE) network: past, present, and future O Gottesman, H Kuivaniemi, G Tromp, WA Faucett, R Li, TA Manolio, ... Genetics in Medicine 15 (10), 761-771, 2013 | 609 | 2013 |
| Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study FE Dewey, MF Murray, JD Overton, L Habegger, JB Leader, SN Fetterolf, ... Science 354 (6319), aaf6814, 2016 | 566 | 2016 |
| A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose GM Cooper, JA Johnson, TY Langaee, H Feng, IB Stanaway, UI Schwarz, ... Blood, The Journal of the American Society of Hematology 112 (4), 1022-1027, 2008 | 538 | 2008 |
| Renin-angiotensin system gene polymorphisms and atrial fibrillation CT Tsai, LP Lai, JL Lin, FT Chiang, JJ Hwang, MD Ritchie, JH Moore, ... Circulation 109 (13), 1640-1646, 2004 | 513 | 2004 |