Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes J Yang, J Huang, M Dasgupta, N Sears, M Miyagi, B Wang, MR Chance, ... Proceedings of the National Academy of Sciences 107 (50), 21499-21504, 2010 | 363 | 2010 |
STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor Y Wang, AHH van Boxel-Dezaire, HJ Cheon, J Yang, GR Stark Proceedings of the National Academy of Sciences 110 (42), 16975-16980, 2013 | 345 | 2013 |
The JAK-STAT pathway at 30: Much learned, much more to do RL Philips, Y Wang, HJ Cheon, Y Kanno, M Gadina, V Sartorelli, ... Cell 185 (21), 3857-3876, 2022 | 244 | 2022 |
TPCA-1 is a direct dual inhibitor of STAT3 and NF-κB and regresses mutant EGFR-associated human non–small cell lung cancers J Nan, Y Du, X Chen, Q Bai, Y Wang, X Zhang, N Zhu, J Zhang, J Hou, ... Molecular cancer therapeutics 13 (3), 617-629, 2014 | 105 | 2014 |
Responses to cytokines and interferons that depend upon JAKs and STATs GR Stark, HJ Cheon, Y Wang Cold Spring Harbor perspectives in biology 10 (1), a028555, 2018 | 103 | 2018 |
IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression J Nan, Y Wang, J Yang, GR Stark Proceedings of the National Academy of Sciences 115 (15), 3906-3911, 2018 | 100 | 2018 |
Lysine methylation of promoter-bound transcription factors and relevance to cancer GR Stark, Y Wang, T Lu Cell research 21 (3), 375-380, 2011 | 80 | 2011 |
Brevilin A, a novel natural product, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells X Chen, Y Du, J Nan, X Zhang, X Qin, Y Wang, J Hou, Q Wang, J Yang PLoS One 8 (5), e63697, 2013 | 73 | 2013 |
A virus-induced conformational switch of STAT1-STAT2 dimers boosts antiviral defenses Y Wang, Q Song, W Huang, Y Lin, X Wang, C Wang, B Willard, C Zhao, ... Cell Research 31 (2), 206-218, 2021 | 45 | 2021 |
STAT3 mutations correlated with hyper-IgE syndrome lead to blockage of IL-6/STAT3 signalling pathway J He, J Shi, X Xu, W Zhang, Y Wang, X Chen, Y Du, N Zhu, J Zhang, ... Journal of biosciences 37, 243-257, 2012 | 45 | 2012 |
Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer L Liao, ZZ Liu, L Langbein, W Cai, EA Cho, J Na, X Niu, W Jiang, Z Zhong, ... Elife 7, e37925, 2018 | 39 | 2018 |
Negative regulation of type I IFN signaling by phosphorylation of STAT 2 on T387 Y Wang, J Nan, B Willard, X Wang, J Yang, GR Stark The EMBO journal 36 (2), 202-212, 2017 | 29 | 2017 |
Loss of ZIP facilitates JAK2-STAT3 activation in tamoxifen-resistant breast cancer N Zhu, J Zhang, Y Du, X Qin, R Miao, J Nan, X Chen, J Sun, R Zhao, ... Proceedings of the National Academy of Sciences 117 (26), 15047-15054, 2020 | 23 | 2020 |
Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia G Davuluri, M Giusto, R Chandel, N Welch, K Alsabbagh, S Kant, A Kumar, ... Molecular and Cellular Biology 39 (16), e00451-18, 2019 | 23 | 2019 |
Molecular cross‐talk of IL‐6 in tumors and new progress in combined therapy Z Song, D Ren, X Xu, Y Wang Thoracic Cancer 9 (6), 669-675, 2018 | 21 | 2018 |
Bazedoxifene inhibits sustained STAT3 activation and increases survival in GBM SM Wightman, TJ Alban, X Chen, JD Lathia, Y Wang, GR Stark Translational Oncology 14 (11), 101192, 2021 | 13 | 2021 |
Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization Q Song, S Datta, X Liang, X Xu, P Pavicic, X Zhang, Y Zhao, S Liu, J Zhao, ... Cellular & molecular immunology 20 (2), 143-157, 2023 | 12 | 2023 |
STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage C Wang, J Nan, E Holvey-Bates, X Chen, S Wightman, MB Latif, J Zhao, ... Proceedings of the National Academy of Sciences 120 (16), e2216953120, 2023 | 9 | 2023 |
A new STAT3 function: pH regulation Y Wang, GR Stark Cell Research 28 (11), 1045-1045, 2018 | 2 | 2018 |